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Univentricular Heart clinical trials

The registry lists 86 studies for Univentricular Heart across more than 10 countries. 22 are recruiting or about to start. 51 of them are mainly about Univentricular Heart (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.

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Status

Completed
48
Recruiting
21
Withdrawn
5
Terminated
4
Status unknown
4
Active, not recruiting
3

Phase

Phase 2
12
Phase 3
7
Phase 1
5
Phase 4
2
Early Phase 1
1

Where

United States
55
Canada
5
France
4
Japan
4
Germany
4
Brazil
3

Who runs them

Boston Children's Hospital (7) · Emory University (4) · Children's Hospital of Philadelphia (4) · University Hospital, Montpellier (4) · University of Aarhus (3) · University of Michigan (3) · Stanford University (3) · Children's Mercy Hospital Kansas City (3)

What is being tested here

Drugs under test in Univentricular Heart studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Arginine Vasopressin022
Digoxin001
Spironolactone001
Carvedilol001
Ambrisentan001
Tadalafil001
Macitentan011
Colchicine011
Treprostinil001
Sildenafil011

Coming up

1phase 3 study under way
7studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 7

Who these studies take

Of the 21 Univentricular Heart studies recruiting now, 8 (38%) set no upper age limit and 13 (62%) stop at 75 or younger. 16 (76%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (5%) take healthy volunteers.

Recruiting studies that take each age, of 21
AgeWomenMen
108 (38%)8 (38%)
1813 (62%)13 (62%)
3012 (57%)12 (57%)
4012 (57%)12 (57%)
5010 (48%)10 (48%)
658 (38%)8 (38%)
758 (38%)8 (38%)
858 (38%)8 (38%)

Across all 86 studies, recruiting or not: 58% stop at 75 or younger and 58% at 65; 83% take children; 1% are for women only and 0% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Univentricular Heart studies take

Of 20 interventional studies with no phase under Univentricular Heart, half reached primary completion within 44 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase44 mo15–63 · 20 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 14, 2026.

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 50 of 86. Browse all 86 → or search them.