Istaroxime clinical trials
Also written PST2744.
How each study uses Istaroxime is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Get an email when these change. Save the Istaroxime studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
Studies by the year they started
9 studies that test it; most in 2015 (3)
| Year | Studies |
|---|---|
| 2006 | 1 |
| 2009 | 2 |
| 2015 | 3 |
| 2020 | 1 |
| 2024 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 8 · Other 1
Windtree Therapeutics (3) · Debiopharm International SA (2) · Lee's Pharmaceutical Limited (1) · Benjamin Levine (1) · sigma-tau i.f.r. S.p.A. (1) · Seismic Pharmaceuticals Operations LLC (1)
Studies
Open first, then newest update. How each study uses Istaroxime is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 9
- Randomized Evaluation of Istaroxime for Stabilization in Acute Heart Failure-Cardiogenic ShockRecruitingPhase 2/3Seismic Pharmaceuticals Operations LLCNCT07583446Written as istaroxime
- A Safety and Efficacy Trial of Istaroxime for Cardiogenic Shock Stage CActive, not recruitingPhase 1/2Windtree TherapeuticsNCT05975021Written as Istaroxime
- Istaroxime Infusion for 24 Hours in Chinese Healthy VolunteersCompletedPhase 1Lee's Pharmaceutical LimitedNCT02477449Written as istaroxime
- The Safety and Efficacy of Istaroxime for Pre-Cardiogenic ShockCompletedPhase 2Windtree TherapeuticsNCT04325035Written as Istaroxime
- The Clinical Study of the Safety and Efficacy of Istaroxime in Treatment of Acute Decompensated Heart FailureCompletedPhase 2Windtree TherapeuticsNCT02617446Written as Istaroxime
- Hemodynamic Response to Exercise in HFpEF Patients After Upregulation of SERCA2aCompletedEarly Phase 1Benjamin LevineNCT02772068Written as Istaroxime
- Phase I Interaction Study of Istaroxime and Digoxin in Subjects With Stable Heart FailureWithdrawnPhase 1Debiopharm International SANCT00869115Written as Istaroxime
- Safety and Efficacy Study of Istaroxime in Acute Decompensated Heart Failure PatientsWithdrawnPhase 2Debiopharm International SANCT00838253Written as Istaroxime
- A Phase II Trial to Assess Hemodynamic Effects of Istaroxime in Pts With Worsening HF and Reduced LV Systolic FunctionCompletedPhase 2sigma-tau i.f.r. S.p.A.NCT00616161Written as Istaroxime
Codes
What other systems call Istaroxime · ClinicalTrials.gg INT004486
- MeSH (NLM) C468128IstaroximeConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) W8I9H2TPPLISTAROXIMEConfirmed FDA, NLM
- NCI Thesaurus C83849IstaroximeOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C468128 | Istaroxime | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | W8I9H2TPPL | ISTAROXIME | Confirmed FDA, NLM |
| NCI Thesaurus | C83849 | Istaroxime | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.