Shanghai Mental Health Center: Schizophrenia trials

The registry lists 63 Schizophrenia studies with Shanghai Mental Health Center as lead sponsor. 16 are open to participants now and 2 have results posted.

Early Phase 1 1Phase 1 1Phase 2 4Phase 3 4Phase 4 8No phase 48(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Xingqi Daozhi Decoction for Antipsychotic-Induced ConstipationNot yet recruitingNCT07767526Phase 1/2
• Eye-Movement Intervention for Cognitive Impairment Across Schizophrenia SpectrumNot yet recruitingNCT07702526Not applicable
• Multi-target TMS for Schizophrenia Negative SymptomsNot yet recruitingNCT07559084Not applicable
• The Effect of Game-Based Intervention on the Cognition of Schizophrenia PatientsRecruitingNCT07557381Not applicable
• Effects of Gamified Rehabilitation on Cognitive and Psychosocial Outcomes in Inpatients With SchizophreniaRecruitingNCT07557368Not applicable
• Efficacy and Mechanisms of TUS on Cognitive Deficits in Schizophrenia: Based on the Hippocampal-Prefrontal CircuitNot yet recruitingNCT06904092Not applicable
• Prediction and Intervention Effect of Rehabilitation Status for Severe Mental Disorder Patients Based on Multimodal Analysis and AI AgentsRecruitingNCT06904079Not applicable
• Efficacy of Hi-tACS for Schizophrenia Negative SymptomsRecruitingNCT06888726Not applicable
• RTMS for Refractory Auditory Hallucinations Based on Personalized Targets Using MagnetoencephalographyRecruitingNCT06802939Not applicable
• Evaluating Pharmacogenomics-Based Pharmacotherapy in Real-World Settings for SchizophreniaNot yet recruitingNCT06700967
• A Study on the Preference of Risperidone Dosage FormsRecruitingNCT06657430
• Efficacy and Safety of Combo-stim Deep Brain Stimulation for Treatment-refractory Mental DisordersRecruitingNCT06112067Not applicable
• Hippocampus DBS in Treatment-resistant SchizophreniaRecruitingNCT05694000Not applicable
• rTMS for Auditory Hallucinations Guided by MagnetoencephalographyRecruitingNCT05598450Not applicable
• Mental Health During the Whole Life Cycle of Community Patients With SchizophreniaRecruitingNCT05159349
• An Observational Study on Atypical Antipsychotics Long-term Treatment Patients With SchizophreniaRecruitingNCT02640911
• Naltrexone and Bupropion Combination on Obese,Smoking Patients With SchizophreniaCompletedNCT02736474Phase 4Results posted
• Study of Repetitive Transcranial Magnetic Stimulation in the Treatment of Cognitive Impairment in SchizophreniaCompletedNCT01940939Not applicableResults posted
• Precise Intervention Technology and Application of Low Intensity TUS on Negative Symptoms of SchizophreniaCompletedNCT05985993Not applicable
• Acupuncture Treatment for Schizophrenia-related Central ObesityStatus unknownNCT05833009Not applicable
• Predictors of Functional Remission in Discharged Patients With Schizophrenia After Long-term Drug DiscontinuationCompletedNCT05667961
• A Study on the Efficacy of Agomelatine Combined With Antipsychotics to Treat Negative Symptoms in SchizophreniaStatus unknownNCT05646264Phase 4
• Optimal rTMS for Cognitive Deficits and Negative Symptoms in SchizophreniaStatus unknownNCT05599373Not applicable
• Risk Prediction Model of Cardiovascular Events in Patients With SchizophreniaStatus unknownNCT05498571
• Intervention Effect of Shen-based Qigong Exercise on Residual Symptoms of SchizophreniaStatus unknownNCT05310955Not applicable
• The Difference of Grey Matter Volume Among the Patients of SchizophreniaCompletedNCT05262790
• Exploration of the Deep Transcranial Magnetic Stimulation for Treatment Resistant SchizophreniaStatus unknownNCT05167942Not applicable
• Transcranial Alternating Current Stimulation (tACS) for Auditory HallucinationsStatus unknownNCT05159336Not applicable
• Developing Dual-channel Transcranial Alternating Current Stimulations Targeting Negative Symptoms in SchizophreniaCompletedNCT04859504Not applicable
• Efficacy and Mechanisms of Low-intensity Focused Ultrasound on Negative Symptoms in Patients With SchizophreniaStatus unknownNCT04620460Not applicable
• Study on the Gut Microbial Mechanism of Negative Symptoms of SchizophreniaStatus unknownNCT04533724Early Phase 1
• SMART Design to Compare Antipsychotic Treatments in Treatment-Resistant SchizophreniaStatus unknownNCT04528095Phase 3
• Prediction of Violent Behavior in Patients With Schizophrenia by Multimodal Machine LearningStatus unknownNCT04520399
• Clinical Intervention on Cognitive Impairment of Schizophrenia With Metabolic SyndromeSuspendedNCT04518319Phase 2
• Research on Accurate Prediction of Long-term Medication Use for Schizophrenia Based on Cognitive FunctionStatus unknownNCT04513275
• The Effectiveness of Assertive Community Treatment on Schizophrenic PatientsCompletedNCT04511663Not applicable
• Deep Transcranial Magnetic Stimulation for the Treatment of Treatment Resistance SchizophreniaStatus unknownNCT04478032Not applicable
• Atypical Antipsychotics Influence on the Safety of the Heart and Monitoring Indicators Model BuildingStatus unknownNCT04446234Phase 4
• Electroencephalogram (EEG) and Electroconvulsive Therapy(ECT) Response in SchizophreniaCompletedNCT04220099
• Prolactin Change in Chinese Patients With Schizophrenia After Antipsychotics TreatmentCompletedNCT04002258
• The Mid-term Effect of Repeated Transcranial Magnetic Stimulation on SchizophreniaCompletedNCT03940898Not applicable
• Clinical Evaluation of Acupuncture Treatment for Negative Symptoms of SchizophreniaStatus unknownNCT03802838Phase 4
• The Efficacy of Computerized Cognitive Remediation Therapy for Chronic SchizophreniaCompletedNCT03772951Phase 4
• Transcranial Alternating Current Stimulation (tACS) for Cognitive Impairments in Patients With SchizophreniaStatus unknownNCT03756610Not applicable
• The Effect of Repetitive Transcranial Magnetic Stimulation in SchizophreniaWithdrawnNCT03736291Not applicable
• Effects of Hyperprolactinemia Induced by Antipsychotic Drugs on Bone MetabolismStatus unknownNCT03675750
• Effects of Oxytocin on Negative Symptoms and Social Cognition in Schizophrenia and Its Possible MechanismsCompletedNCT03662425Not applicable
• Disturbance of Plasma Cytokine Parameters in Clozapine-Resistant Treatment-Refractory Schizophrenia (CTRS) and Their Association With Combination TherapyCompletedNCT03652974Phase 4
• Modulation of Repetitive Transcranial Magnetic Stimulation on Hippocampal Neurogenesis and Functional Network in Patients With SchizophreniaStatus unknownNCT03608462Not applicable
• High-Definition Transcranial Direct Current Stimulation as a Treatment of Negative Symptoms of SchizophreniaTerminatedNCT03602716Not applicable
• Sequential Multiple-Assignment Randomized Trials to Compare Antipsychotic Treatments(SMART-CAT)CompletedNCT03510325Phase 3
• Adjunctive Selective Estrogen Receptor Modulators on Negative and Cognitive Symptoms of Schizophrenia in WomenCompletedNCT03418831Phase 4
• Validating and Optimizing Model of Antipsychotics SelectionStatus unknownNCT03237052Not applicable
• Sodium Butyrate For Improving Cognitive Function In SchizophreniaWithdrawnNCT03010865Phase 2/3
• Magnetic Seizure Therapy Versus Electroconvulsive Therapy for SchizophreniaCompletedNCT03007628Not applicable
• 50 Hz vs. 25 Hz Magnetic Seizure Therapy for SchizophreniaCompletedNCT03003156Not applicable
• The Optimal Treatment for Treatment-resistant SchizophreniaStatus unknownNCT02926976Not applicable
• Repetitive Transcranial Magnetic Stimulation for the Treatment of Negative Symptoms in Schizophrenia Patients.Status unknownNCT02842034Not applicable
• Transcranial Direct Current Stimulation (tDCS) as a Treatment for Cognitive Deficits in SchizophrenicCompletedNCT02748083Not applicable
• Magnetic Seizure Therapy for SchizophreniaTerminatedNCT02746965Not applicable
• The Influence of Omega-3 Fatty Acid on the Violence of Schizophrenia Patient and the Possible MechanismStatus unknownNCT02552758Not applicable
• A Study To Evaluate The Efficacy And Safety Of Intramuscular Levosulpiride In Patients With Agitation Of SchizophreniaCompletedNCT00866645Phase 2/3
• A Study to Evaluate the Efficacy and Safety of Seroquel in Chinese Han Patients With SchizophreniaCompletedNCT00817648Phase 4