AstraZeneca: Schizophrenia trials

The registry lists 79 Schizophrenia studies with AstraZeneca as lead sponsor. 0 are open to participants now and 14 have results posted.

Phase 1 2Phase 2 5Phase 3 20Phase 4 10No phase 42(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Compare the Effect on Cognitive Functioning of Two Formulations of Seroquel, Seroquel XR and IR in Patients With Stable SchizophreniaCompletedNCT01213836Phase 4Results posted
• Efficacy and Safety of SEROQUEL Extended Release (XR) in Acute SchizophreniaCompletedNCT00954122Phase 4Results posted
• Efficacy and Safety of Quetiapine Fumarate in the Treatment of Schizophrenic PatientsCompletedNCT00882518Phase 3Results posted
• Seroquel XR in Adults With SchizophreniaTerminatedNCT00852631Phase 3Results posted
• Study of the Efficacy and Safety of Quetiapine Fumarate Extended Release (Seroquel XR)CompletedNCT00779506Phase 4Results posted
• Phase IIA Study in Patients With SchizophreniaCompletedNCT00686998Phase 2Results posted
• Schizophrenic Patients in Integrated CareTerminatedNCT00681629Phase 4Results posted
• Study to Asses Pharmacodynamics, Pharmacokinetics, Safety and Tolerability of AZD0328 in Patients With SchizophreniaTerminatedNCT00669903Phase 2Results posted
• Study in Schizophrenic In-patients Treated With Quetiapine Prolong or Oral Risperidone at Flexible DoseTerminatedNCT00660595Phase 3Results posted
• Study Evaluating the Clinical Benefit of SEROQUEL XR in Subjects With SchizophreniaCompletedNCT00640601Phase 3Results posted
• Quetiapine Extended Release Depression SymptomsCompletedNCT00640562Phase 3Results posted
• Comparison of the Subjective Well-being and Tolerability of Quetiapine XR to RisperidoneCompletedNCT00600756Phase 3Results posted
• Quetiapine Fumarate (SEROQUEL) in the Treatment of Adolescent Patients With Schizophrenia and Bipolar I DisorderCompletedNCT00227305Phase 3Results posted
• A Study of the Cataractogenic Potential of Seroquel and Risperdal in the Treatment of Participants With Schizophrenia or Schizoaffective DisorderCompletedNCT00206102Phase 4Results posted
• Physician Survey on Monitoring of Patients Treated With QuetiapineCompletedNCT01795326
• EMR Data to Assess Monitoring of Patients Treated With QuetiapineCompletedNCT01793324
• Description of the Use of Quetiapine Extended Release (XR) in Real-life Practice in France. An Observational StudyCompletedNCT01689389
• Observe Real-life Allocation of Atypical Antipsychotics in the Acute Inpatient Management of SchizophreniaCompletedNCT01544608
• Atypical Antipsychotics in the Treatment of Affective Symptoms of Schizophrenia in HungaryCompletedNCT01534936
• Non-interventional Study: Real-life Use of Atypical Antipsychotics in Acute Inpatient Management of SchizophreniaCompletedNCT01491412
• General Practice Research Database Seroquel XR Safety StudyCompletedNCT01447082
• A Study to Observe Real-life Allocation of Antipsychotics in Acute Inpatient Management of SchizophreniaCompletedNCT01394601
• IBIS: Italian Burden of Illness on Schizophrenia & Bipolar DisorderCompletedNCT01392482
• The Purpose of the Study is to Gain an In-depth Picture of the Patient Management and Prescription BehavioursCompletedNCT01377896
• PHARMO Institute Seroquel Safety StudyCompletedNCT01342120
• A Retrospective Non-interventional Study to Evaluate the Use of Seroquel Extended Release (XR) and Immediate Release (IR) in the Clinical Practice of Inpatients With SchizophreniaCompletedNCT01214135
• A Retrospective NIS to Evaluate the Use of Seroquel XR and IR in the Clinical Practice of Outpatients With SchizophreniaCompletedNCT01212575
• Seroquel XR in the Long Term Treatment of SchizophreniaCompletedNCT01202617
• Effectiveness of Atypical Antipsychotics on Anhedonic Features in Patients With SchizophreniaCompletedNCT01160679
• Observational Study to Evaluate Bipolar Disorder Symptoms in Patients Presented With Schizophrenia or DepressionCompletedNCT01028196
• A Study Evaluating the Treatment Selection and Outcome When Changing Antipsychotic Treatment in Schizophrenic PatientsCompletedNCT00999895
• Seroquel XR in Schizophrenia Relapse PreventionCompletedNCT00990626
• The Effects AZD8529 on Cognition and Negative Symptoms in SchizophrenicsCompletedNCT00986531Phase 1
• Epidemiology of Schizophrenia in BulgariaCompletedNCT00984373
• Non-interventional (NI) Study to Observe Efficacy and Usage of Quetiapine in Acute Episodes of Schizophrenia and as Maintenance Therapy Following Standard Clinical Practice in CroatiaCompletedNCT00981123
• Nis Register Study Comparing Seroquel and Seroquel ProlongCompletedNCT00965536
• Non-interventional Open Label Study to Investigate the Effect of Quetiapine XR on Patient Satisfaction and Quality of Life in Patients With SchizophreniaCompletedNCT00934726
• A Non-interventional Study Evaluating the Clinical Benefit and Effectiveness of Quetiapine Fumarate ExtendedCompletedNCT00922090
• Study to Assess the Efficacy, Safety, and Tolerability of AZD8529 in Adult Schizophrenia PatientsCompletedNCT00921804Phase 2
• Seroquel (Quetiapine Fumarate) InPractice Evaluation ProgrammeCompletedNCT00921362
• Evaluate the Pharmacokinetics of Quetiapine Fumarate in Chinese Schizophrenic PatientsCompletedNCT00919607Phase 1
• Effect of Daily Short Message System (SMS) Reminders on Medication Adherence to Oral Antipsychotics in Patients With SchizophreniaCompletedNCT00873249
• Subjective Well Being of Schizophrenic Patients in GreeceCompletedNCT00857064
• NIS to Observe Improvement in Global Assessment of Functioning in Patients With SchizophreniaCompletedNCT00833456
• Study of Mental Care in SpainCompletedNCT00824031
• Observational Study to Evaluate Efficacy and Remission Status for Schizophrenia Patients Under Atypical TreatmentCompletedNCT00809731
• Four Dimensions in SchizophreniaCompletedNCT00782899
• Observation of Change in Clinical Global Impression Scores in Schizophrenia Patients Receiving Seroquel XR TreatmentCompletedNCT00758251
• Non-interventional Study -Observe Treatment Efficacy in Maintaining Symptoms Control in Schizophrenia With Seroquel XRCompletedNCT00750087
• Validity of the Spanish Version of Subjective Well-being Under Neuroleptics Scale (SWN-K) in Patients With SchizophreniaCompletedNCT00749970
• Spanish Validation of Tool Questionnaire to Assess Patients´Perception About Antipsychotic TreatmentCompletedNCT00692133
• Safety and Efficacy of Switching to Quetiapine in Outpatients With SchizophreniaCompletedNCT00690365
• Evaluating Subjective Well-being in Schizophrenic Patients Treated With quetiapineXR® and Other Atypical AntipsychoticsCompletedNCT00689325
• Schizophrenic Patients Taking Part in Integrated Care ProgramTerminatedNCT00617214
• Quality of Life in Schizophrenic PatientsCompletedNCT00597168
• Effectiveness of Anti-Psychotic in GPs SettingCompletedNCT00543088
• Unraveling the Relation of Patient's Profile and Therapeutical Effects of Atypicals, Including Quetiapine EffectCompletedNCT00534222
• A Non-interventional Naturalistic Project to Investigate the Effect of the Use of SMS Text Service on Treatment Adherence in Patients Treated With Seroquel® (Quetiapine)CompletedNCT00533260
• Proof of Concept Study of Cognitive Improvement in Patients With SchizophreniaCompletedNCT00528905Phase 2
• Seroquel Long-Term NIS for Schizophrenia PatientsCompletedNCT00523783
• FAST-A Study to Evaluate the Efficacy and Safety of Quetiapin IR in Patients With Acute PsychosisTerminatedNCT00486798Phase 3
• Rapid Versus Conventional Titration of Quetiapine in Schizophrenia/Schizoaffective DisorderTerminatedNCT00457899Phase 3
• Study of Efficacy and Safety of Seroquel (Quetiapine Fumarate) as Mono-Therapy for Acute SchizophrenicCompletedNCT00428350Phase 4
• Seroquel STACK Study in Schizophrenic or Schizoaffective SubjectsCompletedNCT00328978Phase 3
• Effect of Quetiapine on Negative Symptoms and CognitionCompletedNCT00305422Phase 3
• Fast Titration in the Treatment of Schizophrenia, TaiwanCompletedNCT00304473Phase 3
• Seroquel® Combined With Cognitive Remediation Therapy to Conventional Treatment in Patients With SchizophreniaCompletedNCT00255515Phase 4
• Fast Titration Of Quetiapine Versus Currently Approved TitrationCompletedNCT00254813Phase 3
• Rapid Dose Escalation of Quetiapine Versus Conventional Escalation in Acute Schizophrenic PatientsCompletedNCT00254787Phase 2
• Safety and Efficacy of Seroquel in First Episode SchizophreniaCompletedNCT00254241Phase 4
• Seroquel Switching Study: Feasibility of Switching Any Antipsychotic Treatment to Seroquel in Patients With SchizophreniaCompletedNCT00234377Phase 3
• Relapse Prevention, RoW: Study to Evaluate Prevention of Relapse in Patients in Stable Chronic Schizophrenia Receiving Either Seroquel or PlaceboCompletedNCT00228462Phase 3
• Seroquel on Glucose MetabolismCompletedNCT00214578Phase 4
• Immediate Release (IR) to Sustained Release (SR) Switching Study: Study of Switching From IR Seroquel to SR Seroquel in Outpatients With SchizophreniaCompletedNCT00206128Phase 3
• SR-Registration Study 1, ROW: Efficacy and Safety of Seroquel® in the Treatment of Patients With SchizophreniaCompletedNCT00206115Phase 3
• Quetiapine Fumarate (SEROQUEL) Compared to Placebo in the Treatment of Adolescent Patients With SchizophreniaCompletedNCT00090324Phase 3
• Efficacy & Safety of Quetiapine Fumarate (SEROQUEL) & Placebo in the Treatment of Acutely Ill Patients With SchizophreniaCompletedNCT00085891Phase 3
• A Comparison of Seroquel vs. Risperidone in SchizophreniaCompletedNCT00034905Phase 4
• CAFE Comparison of Atypicals in First Episode of PsychosisCompletedNCT00034892Phase 3