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Schizophrenia, Treatment-Resistant clinical trials

The registry lists 53 studies for Schizophrenia, Treatment-Resistant across more than 10 countries. 22 are recruiting or about to start. 44 of them are mainly about Schizophrenia, Treatment-Resistant (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.

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Status

Completed
17
Recruiting
16
Not yet recruiting
6
Terminated
5
Status unknown
5
Active, not recruiting
2

Phase

Phase 4
8
Phase 3
6
Phase 2
6
Early Phase 1
1
Phase 1
1

Where

United States
12
Canada
7
China
5
India
4
United Kingdom
4
Brazil
3

Who runs them

All India Institute of Medical Sciences, Bhubaneswar (4) · Shanghai Mental Health Center (4) · Ciusss de L'Est de l'Île de Montréal (3) · Centre for Addiction and Mental Health (3) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (2) · University of Sao Paulo (2) · Hospital de Clinicas de Porto Alegre (1) · King's College London (1)

What is being tested here

Drugs under test in Schizophrenia, Treatment-Resistant studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Aripiprazole101
Paliperidone101
Evenamide111
Atenolol101
Ivabradine101
Riluzole101
Clozapine012
Dextromethorphan001
Rituximab001
Scopolamine001

Drug classes tested here Antipsychotics 1 open

Coming up

3phase 3 studies under way
6studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 6, phase 3 first

Who these studies take

Of the 16 Schizophrenia, Treatment-Resistant studies recruiting now, 6 (38%) set no upper age limit and 10 (63%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (13%) take healthy volunteers.

Recruiting studies that take each age, of 16
AgeWomenMen
100 (0%)0 (0%)
1814 (88%)14 (88%)
3016 (100%)16 (100%)
4016 (100%)16 (100%)
5016 (100%)16 (100%)
659 (56%)9 (56%)
757 (44%)7 (44%)
856 (38%)6 (38%)

Across all 53 studies, recruiting or not: 70% stop at 75 or younger and 66% at 65; 6% take children; 0% are for women only and 0% for men only; 4% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

What changed recently

From the registry's own updates since Oct 14, 2026.

Newly registered2

Studies

Recruiting first, then most recently updated. Showing 50 of 53. Browse all 53 → or search them.