GlaxoSmithKline: Renal Insufficiency trials

The registry lists 16 Renal Insufficiency studies with GlaxoSmithKline as lead sponsor. 1 are open to participants now and 5 have results posted.

Phase 1 12Phase 2 2Phase 3 1Phase 4 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study to Investigate the Effects of Moderate or Severe Renal Impairment (RI) on VelzatinibNot yet recruitingNCT07867171Phase 1
• A Study of Belantamab Mafodotin Monotherapy in Multiple Myeloma Participants With Normal and Varying Degree of Impaired Renal FunctionActive, not recruitingNCT04398745Phase 1Results posted
• Pharmacokinetic Study of Gepotidacin in Subjects With Varying Degrees of Renal Impairment and in Subjects With Normal Renal FunctionCompletedNCT02729038Phase 1Results posted
• 4 Week Switch Study in Hemodialysis-dependent Subjects With Anemia Associated With Chronic Kidney DiseaseCompletedNCT01587924Phase 2Results posted
• A Study of the Efficacy and Safety of Albiglutide in Subjects With Type 2 Diabetes With Renal Impairment.CompletedNCT01098539Phase 3Results posted
• Pharmacokinetics, Safety And Toleration Of Maraviroc Administered To Subjects With Various Degrees Of Renal Impaired And Normal Renal FunctionCompletedNCT00717067Phase 4Results posted
• A Study to Evaluate Blood Levels of Bepirovirsen in Adult Participants With Severe or Moderate Kidney DiseaseActive, not recruitingNCT07168356Phase 1
• Pharmacokinetics Study of GSK1265744 in Subjects With Severe Renal ImpairmentCompletedNCT02354937Phase 1
• A Study to Assess the Pharmacokinetics, Safety and Tolerability of Repeat Oral Doses of Darapladib (SB-480848) in Subjects With Severe Renal ImpairmentCompletedNCT01711723Phase 1
• Study to Assess the Safety and PK of GSK573719 and GSK573719/GW642444(VI) Combination in Healthy Subjects and Subjects With Severe Renal ImpairmentCompletedNCT01571999Phase 1
• A Study to Assess the Effects of Repeat Doses of Fluticasone Furoate and GW642444M Combination in Healthy Subjects and in Subjects With Severe Impairment.CompletedNCT01266980Phase 1
• Repeat Dose Safety and Efficacy Study for Compound to Treat AnemiaCompletedNCT01047397Phase 2
• A Comparison Of Study Drug Blood Levels After One Dose Of GSK189075 In Subjects With Normal And Reduced Kidney FunctionCompletedNCT00501462Phase 1
• A Phase I Topotecan Study in Subjects With Cancer and Impaired Renal FunctionCompletedNCT00483860Phase 1
• Study Of SB-497115 in Healthy Subjects and Subjects With Mild, Moderate or Severe Renal ImpairmentCompletedNCT00442871Phase 1
• Observational Pharmacokinetic Study Of GW679769 In Subjects With Renal ImpairmentCompletedNCT00358813Phase 1