Pfizer: Renal Insufficiency trials

The registry lists 37 Renal Insufficiency studies with Pfizer as lead sponsor. 2 are open to participants now and 15 have results posted.

Phase 1 24Phase 2 1Phase 3 4Phase 4 8No phase 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study to Learn About the Study Medicine Called Prifetrastat in People With Renal ImpairmentNot yet recruitingNCT07933848Phase 1
• A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With Reduced Kidney FunctionRecruitingNCT07315360Phase 1
• A Clinical Trial of the Study Medicine (PF-07081532) in People With Diabetes and Kidney DysfunctionTerminatedNCT05510245Phase 1Results posted
• A Study to Measure the Amount of Study Medicine in Blood in Adult Participants With COVID-19 and Severe Kidney DiseaseTerminatedNCT05487040Phase 1Results posted
• Renal Impairment Study of PF-07321332 Boosted With Ritonavir in Adult Participants With Renal Impairment and in Healthy Participants With Normal Renal Function.CompletedNCT04909853Phase 1Results posted
• STUDY OF PF-06882961 IN PARTICIPANTS WITH TYPE 2 DIABETES MELLITUS WITH VARYING DEGREES OF RENAL IMPAIRMENT AND PARTICIPANTS WITHOUT RENAL IMPAIRMENTCompletedNCT04616027Phase 1Results posted
• Pharmacokinetic Study of Aztreonam-Avibactam in Severe Renal ImpairmentCompletedNCT04486625Phase 1Results posted
• Renal Impairment Study of PF-06700841CompletedNCT04260464Phase 1Results posted
• A Renal Impairment Study for PF-06651600TerminatedNCT04037865Phase 1Results posted
• A Renal Impairment Study for PF-04965842CompletedNCT03660241Phase 1Results posted
• Lorlatinib Renal Impairment StudyCompletedNCT03542305Phase 1Results posted
• Use Of Fragmin In HemodialysisCompletedNCT01879618Phase 3Results posted
• PF-04634817 Renal Impairment StudyCompletedNCT01791855Phase 1Results posted
• Pharmacokinetics Of CP-690,550 In Patients With Impaired Renal FunctionCompletedNCT01740362Phase 1Results posted
• Study Of The Safety And Efficacy Of Conversion From A CNI To Sirolimus In Renally-Impaired Heart Transplant RecipientsCompletedNCT00369382Phase 4Results posted
• Study Comparing Effect On Carotid Atherosclerosis Following Conversion From Tacrolimus To Sirolimus Post-Transplant In Kidney Transplant PatientsTerminatedNCT00311311Phase 3Results posted
• A Study Comparing the Withdrawal of Steroids or Tacrolimus in Kidney Transplant RecipientsCompletedNCT00195429Phase 4Results posted
• A Study to Learn About the Study Medicine - Zavicefta in Patients With Sepsis or Loss of Kidney Function in JapanActive, not recruitingNCT06864585
• A Study to Learn How Renal Impairment Affects the Pharmacokinetics of PF-07817883.CompletedNCT06586216Phase 1
• A Study to Learn How the Body Processes the Study Medicine Called PF-07923568 in People With Loss of Kidney FunctionCompletedNCT06037031Phase 1
• Study of GBT021601 in Participants With Renal ImpairmentTerminatedNCT05878704Phase 1
• Glasdegib Renal Impairment StudyCompletedNCT03596567Phase 1
• Single-Dose PK Study of GBT440 in Subjects With Renal ImpairmentCompletedNCT03161015Phase 1
• Study Of Palbociclib (PD-0332991) In Renal ImpairmentCompletedNCT02085538Phase 1
• A Study to Evaluate The Pharmacokinetics Of Crizotinib (PF-02341066) In Subjects With Impaired Renal FunctionCompletedNCT01419041Phase 1
• Bosutinib In Subjects With Renal ImpairmentCompletedNCT01233882Phase 1
• A Phase 1, Non-Randomized, Open-Label, Single-Dose Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF 01913539] In Subjects With Severely-Impaired And Normal Renal FunctionCompletedNCT00824590Phase 1
• A Single Dose Study Investigating the Elimination as Well as the Tolerability of PD 0332334 in Healthy Subjects as Compared to Patients With Impaired Kidney Function.TerminatedNCT00721422Phase 1
• Study Evaluating Sirolimus in the Treatment of Kidney TransplantCompletedNCT00282217Phase 4
• Study Comparing Conversion From Calcineurin Inhibitors to Rapamune Versus Standard Therapy in Established Renal Allograft RecipientsCompletedNCT00273871Phase 3
• Study Comparing Two Sirolimus Regimens vs. Tacrolimus and Mycophenolate Mofetil Regimen in Kidney Transplant RecipientsCompletedNCT00266123Phase 4
• Study Comparing Two Immunosuppressive Regimens in De Novo Renal Allograft RecipientsCompletedNCT00261820Phase 4
• Study Evaluating Two Different Sirolimus-based Immunosuppressive Regimens in Elderly Kidney Transplant RecipientsCompletedNCT00254709Phase 4
• Study Evaluating Sirolimus in Kidney Transplant Recipients in IndiaCompletedNCT00195481Phase 4
• Study Comparing Cyclosporine Dose Reduction vs. Cyclosporine Elimination in Kidney Transplant Recipients Taking SirolimusCompletedNCT00195468Phase 4
• Study Evaluating Sirolimus in Kidney Transplant Recipients.CompletedNCT00167947Phase 3
• An Open-Label Study To Assess The Pharmacokinetics, Safety And Toleration Of Vfend®; Following Multiple Dosing With VfendTerminatedNCT00150319Phase 1/2