An interventional study of Mediterranean diet and Pilates exercise in Polycystic Ovary Syndrome, sponsored by Cairo University. Not yet recruiting at 1 site in Egypt. Open to female participants aged 25 Years to 35 Years. Per ClinicalTrials.gov, last updated 2026-11-13.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
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Among 34 studies in Polycystic Ovary Syndrome by Cairo University — 10 open to participants now, 10 under way, none of them phase 3. Polycystic Ovary Syndrome · Cairo University.
Among the 34 studies in Polycystic Ovary Syndrome by Cairo University, this one is the 17th largest by planned enrollment of the 26 interventional ones that give a count, is one of 4 that started in 2026, is one of 20 with no phase, and was the 34th registered.
958 studies on the registry are indexed under Polycystic Ovary Syndrome; 175 are open to participants now.
Browse Polycystic Ovary Syndrome studies →10 of the 34 studies in Polycystic Ovary Syndrome by Cairo University are open now, in 1 country. Recruiting first, the newest first:
Cairo University · Sites in Egypt
Ages 20–40 · Women only
Cairo University · Sites in Egypt
Ages 20–30 · Women only
Cairo University · Sites in Egypt
Ages 30–40 · Women only
Cairo University · Sites in Egypt
Ages 35–45 · Women only
Cairo University · Sites in Egypt
Ages 18–35 · Women only
By country, each count listing its studies:
Of the 119 Polycystic Ovary Syndrome studies recruiting now, 11 (9%) set no upper age limit and 105 (88%) stop at 75 or younger; 23 take children under 18; 41 take healthy volunteers.
This study: 25 Years to 35 Years · female · no healthy volunteers.
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34 studies; the count open now beside each. This study's row is marked.
First in 2013; this study’s year is marked. 4 started in 2026.
By drug class, each counting the studies that test any of its medicines:
This study's planned enrollment of 40 is below the median of 70 across 698 interventional studies indexed under Polycystic Ovary Syndrome.
Median enrollment 55 across the 26 interventional studies, 98 across the 8 observational. Of the 17 that completed or were terminated, 1 (6%) have results posted.
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Cairo University is the lead sponsor of 4,951 studies on the registry; 1,463 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
3 of the studies in Polycystic Ovary Syndrome by Cairo University that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07591246Cairo UniversityEfficay of Physical Activity Program in PCOS Females With Fatty Pancrease and Thyroid Hypofunction | 2026-12-30 |
| NCT07708766Cairo UniversityEffect of High Intensity Interval Training on Insulin Resistance in Polycystic Ovarian Syndrome | 2027-01-15 |
| NCT07937202Cairo UniversityEffects of Pilates Exercises on Doppler Parameters in Obese Females With Polycystic Ovarian Syndrome | 2027-04-15 |
Add all 3 to your calendar (.ics) → With an account.
Among the 34 studies in Polycystic Ovary Syndrome by Cairo University, from their registry updates:
This tab as a report to print or save as PDF → With an account.
The purpose of this study is to determine the effect of Pilates exercises on Doppler parameters in obese females with polycystic ovarian syndrome.
Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder that impacts many women of the reproductive age worldwide. Depending on diagnostic criteria, this disorder affects ∼6% to 20% of reproductive aged women, with symptoms of PCO arise during the early pubertal years Pilates exercises are a set of specialized and combined exercises of both body and mind. Pilates lead to are markable decrease in body weight, BMI, lean body mass, and waist circumference in obese adults and this lead to decrease insulin resistance in obese PCO. Pilates exercises played an important role in improving physical fitness, body composition, metabolic disorders, and depression in women. It was reported that 30-45 min Pilates exercise could produce positive changes in energy expenditure, thus reducing body weight.
There is dearth of knowledge regarding the effect of weight loss interventions on Doppler parameters in obese PCOS females. Therefore, this study will be conducted to provide physiotherapists with a scientific updated knowledge, concerning effect of Pilates exercises on Doppler parameters in obese females with PCOS, aiming to normalize their Doppler parameters. This study may expand role of physiotherapy in woman's health.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
All polycystic ovarian syndrome (PCOS) females will have two of the 3 features of Rotterdam criteria for the diagnosis of PCOS which include oligo or anovulation, clinical and/or biochemical signs of hyperandrogenism (i.e. hirsutism, acne, male pattern balding, elevated serum androgens), and polycystic ovaries on ultrasound.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The participants will receive Mediterranean diet program, for 8 weeks.
Other: Mediterranean diet
The participants will receive the same Mediterranean diet program, in addition to Pilates exercises, three times per week, for 8 weeks.
Other: Mediterranean diet · Other: Pilates exercise
Diet aimed to restrict the intake of sweets and foods containing trans fatty acids. The participants had a maximum carbohydrate intake of less than 20%, a maximum carbohydrate intake of 100 g throughout the day and an increased intake of protein and fat. Participants were advised to consume whole grain as a staple food, a high intake of extra virgin olive oil, vegetables (including green leafy vegetables, fruit, cereals, nuts, and legumes), moderate intake of fish and other meat, dairy products, and a low intake of eggs
It includes 5 Pilates exercises including bridge marching exercise, single-leg circles exercise, rolling like a ball exercise, plank to pike exercise, and side kneeling circles. The exercises will be performed 3 times per week for 8 weeks.
Body weigh (kilograms)
Body weight will be measured by weight scale (kilograms) for all participants before and after treatment
Time frame: 8 weeks
Body height (meter)
The height will be measured by height scale in meters for all participants before and after treatment
Time frame: 8 weeks
Body mass index
Weight-height scale will be used to measure body weight and height of each female in both groups before and after the end of treatment procedures to calculate body mass index.
Time frame: 8 weeks
Waist-hip ratio
Tape measurement will be used to measure circumference of waist and hip for all participated females in both groups before and after the end of treatment procedures to calculate Waist-hip ratio.
Time frame: 8 weeks
Peak systolic velocity (PSV)
The colour Doppler ultrasound will be used to measure peak systolic velocity (PSV). PSV reflects the extent of vascular filling and blood supply.
Time frame: 8 weeks
end-diastolic velocity (EDV)
The colour Doppler ultrasound will be used to measure the end-diastolic velocity (EDV). EDV reflects the blood perfusion situation of the distal tissue and numerical drop shows shortage of distal blood supply.
Time frame: 8 weeks
Resistance index (RI)
The Colour Doppler ultrasound will be used to measure the resistance index (RI). RI will be calculated as difference between Peak systolic velocity (PSV) and end-diastolic velocity (EDV) divided by Peak systolic velocity (PSV). RI reflects impedance to blood flow, and lower values of RI and PI indicate higher blood flow.
Time frame: 8 weeks
Pulsatility index (PI)
The Colour Doppler ultrasound will be used to measure the Pulsatility index (PI). PI will be calculated as the difference between Peak systolic velocity (PSV) and end-diastolic velocity (EDV) divided by the mean maximum flow velocity. PI reflects impedance to blood flow, and lower values of RI and PI indicate higher blood flow.
Time frame: 8 weeks
Ovarian volume
The ovarian volume will be measured by the ultrasonography. it is one of the diagnostic criteria of polycystic ovarian syndrome (more than 10 ml).
Time frame: 8 weeks
36-Item Short Form Health Survey (SF-36)
It will be used to evaluate health-related quality of life for each participants in both groups before and after the treatment course. It is a 36 item-scale which covers two categories: physical component summary and mental component summary. Each item falls on a 0-100 scale. Higher values indicate better health.
Time frame: 8 weeks
Start is estimated for Nov 2026; primary completion for Apr 2027, 5 months later.
Of 203 non-industry interventional studies with no phase under Polycystic Ovary Syndrome, half reached primary completion within 18 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 37. This study's planned 5 months is below that.
Counting every sponsor, half of 218 studies reached it within 18 months; a quarter within 7 and three quarters within 37.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.
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