Progestins clinical trials
A class of medicines: the studies that test any of its 6 members, each study once. Members are as MeSH files each medicine’s actions, and as the NCI Thesaurus classes newer ones. In MeSH: Progestins.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Medicines in this class
Studies that test each. A study of two counts under both, and once above.
- Gestrinone
- 1
Studies by the year they started
368 studies that test it; most in 2019 (30); 2 more planned to start later
| Year | Studies |
|---|---|
| 1994 | 1 |
| 1996 | 1 |
| 1999 | 1 |
| 2000 | 2 |
| 2002 | 4 |
| 2003 | 5 |
| 2004 | 11 |
| 2005 | 8 |
| 2006 | 14 |
| 2007 | 9 |
| 2008 | 13 |
| 2009 | 23 |
| 2010 | 13 |
| 2011 | 19 |
| 2012 | 16 |
| 2013 | 16 |
| 2014 | 14 |
| 2015 | 18 |
| 2016 | 21 |
| 2017 | 22 |
| 2018 | 13 |
| 2019 | 30 |
| 2020 | 18 |
| 2021 | 15 |
| 2022 | 14 |
| 2023 | 13 |
| 2024 | 6 |
| 2025 | 16 |
| 2026 | 12 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 61 · Other 311
Bayer (12) · University of Virginia (10) · University of North Carolina, Chapel Hill (9) · Assiut University (8) · IBSA Institut Biochimique SA (7) · Yale University (7) · University of Minnesota (7) · Ain Shams University (6)
Studies
Open first, then newest update. How each study uses a medicine is read from its arms, and is right about nine times in ten. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing one of them · 372
- Hormone Replacement Therapy in Adolescents With Premature Ovarian InsufficiencyRecruitingPhase 3Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NCT06851754Written as Progesterone
- Efficacy of Progesterone and Low Molecular Weight Heparin in Recurrent Pregnancy LossNot yet recruitingPhase 3General University Hospital, PragueNCT07796737Written as Vaginal Micronized Progesterone (Progesterone Besins)
- Cycle-to-cycle Variability of Progesterone in the Endometrium in Patients Undergoing an Euploid Blastocyst Transfer in a Hormone Replacement Therapy (HRT) Cycle (PROMICOFET)Not yet recruitingPhase 4University Hospital, GhentNCT07818278Written as Progesterone 200 mg vaginal capsules
- First in Human Safety and Ease of Use Assessment of 400mg Progesterone Callavid in Women With Luteal Phase InsufficiencyRecruitingPhase 1Calla Lily Clinical Care LtdNCT07136922Written as Cyclogest 400 mg
- Progesterone Supplementation After Letrozole-stimulated InseminationRecruitingPhase 4Kirstine KirkegaardNCT07508657Written as Progesterone
- Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner SyndromeRecruitingPhase 4Children's Mercy Hospital Kansas CityNCT06834594Written as Micronized progesterone 200 MG
- Progesterone Luteal Support in Unexplained Infertility ManagementNot yet recruitingPhase 3Simone BroerNCT07738068Written as Utrogestan® 200 mg Soft Capsule
- Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and ChildrenRecruitingPhase 4University of MinnesotaNCT04783857Written as Progesterone 200 MG Oral Capsule
- Prolonged Progesterone to Prevent Preterm Birth From IVF - ETRecruitingPhase 4Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityNCT05787509Written as Progesterone Sustained-release vaginal gel
- SHAPE-ENDO: Pilot Randomized Trial of Multimodal Pre-Surgical Optimization Versus Standard Surgery in Patients With Obesity and Early-Stage Endometrial CancerNot yet recruitingPhase 4Hospital Universitari de BellvitgeNCT07462663Written as Oral Progestins
- Exogenous Progesterone as Ovulation TriggerNot yet recruitingPhase 4Instituto Valenciano de Infertilidade de LisboaNCT07466199Written as Vaginal micronized progesterone
- TQB2450 Plus Progestin for Fertility-sparing Treatment in MMRd ECRecruitingPhase 2Fudan UniversityNCT06914297Written as TQB2450 injection + oral progestin
- Individualized Prolonged Luteal Support After Fresh Embryo Transfer in Women With Low ProgesteroneNot yet recruitingPhase 3University Hospital, MontpellierNCT07613528Written as Progesterone Injectable
- The Role of Estradiol and Progesterone on Appetite Regulation and Energy BalanceRecruitingNot applicableWilfrid Laurier UniversityNCT07620587Written as Estradiol and Progesterone Combination
- Menopausal HT for Women Living With HIV (HoT)RecruitingPhase 4Advancing Clinical Therapeutics Globally for HIV/AIDS and Other InfectionsNCT06856174Written as Micronized Progesterone
- Comparing the Pharmacokinetics of a Progesterone Ring Versus a Progesterone Vaginal InsertNot yet recruitingPhase 1Daré Bioscience, Inc.NCT06668896Written as Progesterone
- Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite AthletesEnrolling by invitationNot applicableEnhanced Emirates LimitedNCT07568574Written as Progesterone Cream
- Progesterone to Enhance the Efficacy and Success of Expectantly Managed Preterm Severe/Superimposed PreeclampsiaRecruitingPhase 2University of Mississippi Medical CenterNCT02989025Written as 17 OHPC
- Examining the Effects of Estradiol on Neural and Molecular Response to RewardRecruitingPhase 4University of North Carolina, Chapel HillNCT05282277Written as Micronized Progesterone
- MIcronized PROgesterone in Frozen Embryo Transfer CyclesRecruitingPhase 3Fundación Santiago Dexeus FontNCT05899010Written as Vaginal progesterone 600mg daily
Codes
What other systems call Progestins · ClinicalTrials.gg INT008100
- MeSH (NLM) D011372ProgestinsOne source ClinicalTrials.gov
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D011372 | Progestins | One source ClinicalTrials.gov |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.