Pleural Diseases clinical trials
The registry lists 51 studies for Pleural Diseases across more than 10 countries. 12 are recruiting or about to start. 25 of them are mainly about Pleural Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-02. Counting its 8 narrower conditions too, such as Mesothelioma, Malignant: 920 studies, 191 open.
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Who runs them
Eskisehir Osmangazi University (6) · China-Japan Friendship Hospital (3) · Assiut University (2) · Roswell Park Cancer Institute (2) · Wuhan Union Hospital, China (2) · University of Oxford (2) · Icahn School of Medicine at Mount Sinai (2) · The University Clinic of Pulmonary and Allergic Diseases Golnik (2)
What is being tested here
Drugs under test in Pleural Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Apr 2027The Diagnostic Accuracy and Clinical Value of FAPI PET in Pleural Mesothelioma · Aalborg University Hospital
- May 2027Confocal Laser Endomicroscopy Guided Medical Thoracoscopy for the Diagnosis of Pleural Disease · China-Japan Friendship Hospital
- Aug 2027The Efficacy of Shear-wave Elastography-guided Biopsy for Diagnosis in Pleural Disease · National Taiwan University Hospital
Who these studies take
Of the 7 Pleural Diseases studies recruiting now, 6 (86%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (29%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 7 (100%) | 7 (100%) |
| 30 | 7 (100%) | 7 (100%) |
| 40 | 7 (100%) | 7 (100%) |
| 50 | 7 (100%) | 7 (100%) |
| 65 | 7 (100%) | 7 (100%) |
| 75 | 7 (100%) | 7 (100%) |
| 85 | 7 (100%) | 7 (100%) |
Across all 51 studies, recruiting or not: 4% stop at 75 or younger and 4% at 65; 6% take children; 0% are for women only and 0% for men only; 8% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 51. Browse all 51 → or search them.
- The Diagnostic Accuracy and Clinical Value of FAPI PET in Pleural MesotheliomaRecruitingNCT06790082Phase 21 country
- Study of Hospitalised Patients With Acute Respiratory ConditionsRecruitingNCT050950901 country
- Dual-function Semirigid Thoracoscopy Versus Rigid Thoracoscopy for the Diagnosis of Pleural DiseaseNot yet recruitingNCT07114783Not applicable
- Evaluating the Use of an App in Pleural Disease: Algorithm-supported Clinical Decision Making Versus Usual CareEnrolling by invitationNCT07625176Not applicable1 country
- Confocal Laser Endomicroscopy Guided Medical Thoracoscopy for the Diagnosis of Pleural DiseaseRecruitingNCT06741839Not applicable1 country
- Thoracoscopic Pleural Biopsy in Sohag University HospitalRecruitingNCT06964308Not applicable1 country
- Dual-function Semirigid Thoracoscopy Versus Semirigid Thoracoscopy for the Diagnosis of Pleural Diseases: A Multicenter Open-label Randomized Controlled TrialNot yet recruitingNCT06744725Not applicable1 country
- Strategy for Prompt and Effective Thoracentesis in the Emergency DepartmentRecruitingNCT06180603Not applicable1 country
- Developing a Machine Learning Model to Predict Pleural Adhesion Preoperatively Using Pleural UltrasoundNot yet recruitingNCT064230661 country
- The Efficacy of Shear-wave Elastography-guided Biopsy for Diagnosis in Pleural DiseaseRecruitingNCT06226909Not applicable1 country
- Thoracoscopic Pleural Lavage and Brushing in Undiagnosed Pleural EffusionNot yet recruitingNCT06066398Not applicable
- Prospective Data Collection on Clinical, Radiological and Patient Reported Outcomes After Pleural InterventionRecruitingNCT059101121 country
- Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing SurgeryCompletedNCT03678350Phase 11 country
- Optimal Number of Pleural Biopsies During PleuroscopyCompletedNCT068978781 country
- Photodynamic Therapy to Amplify the Response to Immunotherapy in Patients With Non-small Cell Lung Cancer With Pleural DiseaseTerminatedNCT04836429Phase 11 country
- Erector Spinae Plane Block With Bupivacaine for Medical ThoracoscopyTerminatedNCT06313632Phase 31 country
- Early Intrapleural TPA Instillation Versus LateWithdrawnNCT03167281Phase 41 country
- Mini Invasive Endomicroscopy of the Pleura for Malignancies DiagnosisCompletedNCT047311291 country
- The Oxford Pleural Infection Endotyping StudyCompletedNCT065136891 country
- Fibrinolytic Therapy Versus Medical ThoracoscopyCompletedNCT03213834Phase 41 country
- Vacuum vs Manual Drainage During Unilateral ThoracentesisCompletedNCT03496987Not applicable
- Analysis of Metabonomics for Pleural EffusionCompletedNCT05906823
- Risk of Pneumothorax With and Without Chest Tube Clamping in Patients With Pleural PathologyCompletedNCT05243316Not applicable1 country
- Optical Coherence Tomography of Airway and Pleural DisordersWithdrawnNCT005808921 country
- Impact of Respiratory Physiotherapy in the Management of Infectious Pleural EffusionCompletedNCT02359383Not applicable1 country
- The Diagnosis and Mechanism of Pleural EffusionCompletedNCT039976691 country
- A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General AnesthesiaStatus unknownNCT05077111Phase 41 country
- Pleural Disease: Phenotypes, Diagnostic Yield and OutcomesCompletedNCT039228411 country
- Fibrinolysis Compared to Thoracoscopy for Pleural InfectionCompletedNCT03468933Phase 41 country
- Phase I Trial of Afatinib (BIBW 2992) and Dasatinib in Non-small Cell Lung Cancer (NSCLC)CompletedNCT01999985Phase 11 country
- Analgesic Non Inferiority of the Thoracic Bi-block in Comparison With Thoracic Epidural for VATS.CompletedNCT045382351 country
- Respiratory Function of Dexmedetomidine in Patients Undergoing PleuroscopyCompletedNCT035978281 country
- Rapid Pleurodesis Through an Indwelling Pleural CatheterTerminatedNCT03325192Not applicable1 country
- Suturing With U-Technique Versus Un-Reapproximated Wound Edges During Removal of Closed Thoracostomy Tube DrainStatus unknownNCT04193241Not applicable1 country
- Liquid Biopsy With Immunomagnetic Beads Capture Technique for Malignant Cell Detection in Body FluidStatus unknownNCT028916421 country
- Fibrinolysis Compared to Thoracoscopy for Pleural InfectionCompletedNCT02973139Not applicable1 country
- Talc Outpatient Pleurodesis With Indwelling CatheterStatus unknownNCT03973957Not applicable1 country
- Confocal Laser Endomicroscopy in Pleural MalignanciesStatus unknownNCT032901831 country
- Transthoracic Sonography Versus High Resolution Computed Tomography in Alveolar Intersitial SyndromeStatus unknownNCT03172585Not applicable
- Efficiency and Safety of Pleural Biopsy Methods in the Diagnosis of Pleural DiseasesCompletedNCT03153501Not applicable1 country
- Study Designed to Optimize the Treatment of Primary PneumothoraxStatus unknownNCT02866305Early Phase 11 country
- Cryobiopsy or Forceps Biopsy During Semirigid Thoracoscopy: a Comparative StudyCompletedNCT01475084Phase 2/31 country
- Serum Biomarkers in Diagnosis of MesotheliomaCompletedNCT020291051 country
- Pleural Cryobiopsies During Semirigid Thoracoscopy: A New TechniqueCompletedNCT01472172Early Phase 11 country
- Outcome of Patients Undiagnosed Under Medical ThoracoscopyCompletedNCT013569791 country
- Safety of Thoracoscopy in Patients With High RiskCompletedNCT011934391 country
- Rigid Versus Semirigid Thoracoscopy in Diagnosing Pleural Diseases: a Randomized StudyCompletedNCT01366261Phase 31 country
- Multiple Biomarkers in Undiagnosed Pleural EffusionTerminatedNCT003161341 country
- Efficacy and Security of Intrapleurally Alteplase vs Urokinase for the Treatment of Complicated Parapneumonic Effusion and EmpyemaCompletedNCT01246453Phase 41 country
- Ultrasonography Guided Pleural Biopsy Versus Computed Tomography Guided Pleural BiopsyCompletedNCT01196585Not applicable1 country