An observational study in Pleural Diseases, sponsored by Icahn School of Medicine at Mount Sinai. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-02-04.
Sponsored by Icahn School of Medicine at Mount Sinai · Observational
A single-center, non-randomized, prospective observational, pilot study designed to determine what is the optimal number of pleural biopsies to take during pleuroscopy.
After enrollment, participants will undergo pleural biopsies via pleuroscopy. Specimens will be divided into three aliquots (1-3, 4-6, 7-10), which will be sent to pathology. A designated pathologist will evaluate the specimens in each aliquot to determine the number of biopsies required to reach a diagnosis and to obtain sufficient material for biomarker testing (when needed), and determine whether analysis of further aliquots is needed.
49 studies on the registry are indexed under Pleural Diseases; 13 are open to participants now.
This study's enrollment of 104 is below the median of 152 across 14 observational studies indexed under Pleural Diseases.
Browse Pleural Diseases studies →Icahn School of Medicine at Mount Sinai is the lead sponsor of 764 studies on the registry; 181 are open to participants now.
Of its 121 completed or terminated interventional studies of FDA-regulated products, 82 (68%) have results posted.
Counted across the registry records on this site, refreshed daily.
All adult patients that undergo pleuroscopy for pleural biopsies, excluding those with inability to provide informed consent.
Exclusion Criteria:
- Inability to provide informed consent
All consecutive patients referred for a pleuroscopy.
Number of pleural biopsies to reach a diagnosis
The number of pleural biopsies needed to reach a diagnosis.
Time frame: At week 2 after pleuroscopy
Number of pleural biopsies required for comprehensive biomarker testing.
The number of biopsies required to obtain sufficient material for comprehensive biomarker testing.
Time frame: At week 4 after pleuroscopy
Number of complications
Number of complications related to the biopsy.
Time frame: At week 4 after pleuroscopy
Plan to share: Yes — All of the individual participant data collected during the trial, after deidentification.
Supporting information: Study protocol, Sap, Icf, Csr, Analytic code
No publications or documents are linked to this record.
This study is completed, as verified in Jan 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Icahn School of Medicine at Mount Sinai