ClinicalTrials.gg
Active, not recruitingNCT03665064Updated Mar 16, 2026

Long Term Outcome Study in Patients With Pituitary Disorders

An observational study in Pituitary Diseases and Pituitary Neoplasms, sponsored by University of Alberta. Active, not recruiting. Per ClinicalTrials.gov, last updated 2026-03-16.

Primary conditionPituitary NeoplasmsRegistry: Pituitary DiseasesReclassifiedWhy we changed it
Registry
Pituitary Diseases — the first condition term the registry derived for this study.
ClinicalTrials.gg
Pituitary Neoplasms
Why
  1. The study's listed conditions name Pituitary Neoplasms, a narrower term within Pituitary Diseases.
Confidence
High: the new condition is named in the study's own listed conditions. Of 351 hand-checked studies reclassified this way, 68% were exactly right and 84% in the right disease family; the registry's first term was right for 5% (measured 2026-10-21). How we classify →
Wrong?
Tell us the study's main condition →

Sponsored by University of Alberta · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
1,500
Sex
All
01

Study summary

To determine the outcomes of patients with different pituitary disorders whether they are managed medically, surgically or expectantly.

Read the detailed description

A chart audit of around 1500 patients seen in two specific clinics, the Medical Pituitary Clinic and the combined Endocrine/Neurosurgical Pituitary Clinic at the University of Alberta Hospital, will be performed to determine the effectiveness of various treatment strategies on the long term outcome of specific pituitary disorders. The investigator's will collect retrospective demographic (age, sex, ethnicity), clinical (mode of presentation, hormonal parameters) and therapeutic outcome (surgical, medical, expectant and / or radiation treatment; co-morbidities and complications) of patients seen in these two clinics between January 2000 and December 2020.

02

Conditions studied

  • Pituitary Diseases
  • Pituitary Neoplasms

Browse trials for

Keywords

  • Pituitary tumor
  • Acromegaly
  • Cushing
  • Prolactinoma
03

In context

Pituitary Neoplasms Reclassified

200 studies on the registry are indexed under Pituitary Neoplasms; 51 are open to participants now.

This study's planned enrollment of 1,500 is above the median of 163 across 74 observational studies indexed under Pituitary Neoplasms.

Browse Pituitary Neoplasms studies →

Lead sponsor

University of Alberta is the lead sponsor of 823 studies on the registry; 169 are open to participants now.

Of its 5 completed or terminated interventional studies of FDA-regulated products, 3 (60%) have results posted.

Compared within Pituitary Neoplasms, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Pituitary Diseases. The counts are of registry records indexed under each term, refreshed daily. How we classify →

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

tertiary referral center

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • patients with confirmed pituitary disease

Exclusion criteria

Exclusion Criteria:

  • patients who do not have confirmed pituitary disease
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
1,500 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Progression free survival after pituitary surgery

    Using clinical, biochemical and imaging studies of a cohort of surgically operated patients to identify prognostic factors of tumor recurrence

    Time frame: up to 17 years post surgery

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Jan 2000 (actual). Primary completion is estimated for Dec 2026, 323 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Sep 7, 2018
First posted
Sep 11, 2018
StartActual
Jan 1, 2000
Primary completionEst.
Dec 31, 2026
CompletionEst.
Dec 31, 2026
Last update
Mar 16, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Mar 16, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03665064
Responsible party
Sponsor
First posted
Sep 11, 2018
Start date
Jan 1, 2000
Primary completion
Dec 31, 2026 (estimated)
Completion
Dec 31, 2026 (estimated)
Last update
Mar 16, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Mar 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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