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Locked-In Syndrome clinical trials

The registry lists 21 studies for Locked-In Syndrome across 7 countries. 13 are recruiting or about to start. 9 of them are mainly about Locked-In Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.

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Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

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Status

Recruiting
8
Not yet recruiting
4
Completed
4
Status unknown
2
Terminated
1
Withdrawn
1

Where

United States
12
China
2
Netherlands
2
France
1
Switzerland
1
Denmark
1

Who runs them

Leigh R. Hochberg, MD, PhD. (3) · Second Affiliated Hospital, School of Medicine, Zhejiang University (2) · Oregon Health and Science University (2) · Johns Hopkins University (2) · UMC Utrecht (2) · The University of Texas Health Science Center, Houston (1) · Zhujiang Hospital (1) · Amy Wagner (1)

Coming up

0phase 3 studies under way
4studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 4

Who these studies take

Of the 8 Locked-In Syndrome studies recruiting now, 1 (13%) set no upper age limit and 2 (25%) stop at 75 or younger. 2 (25%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.

Recruiting studies that take each age, of 8
AgeWomenMen
100 (0%)0 (0%)
186 (75%)6 (75%)
308 (100%)8 (100%)
408 (100%)8 (100%)
508 (100%)8 (100%)
658 (100%)8 (100%)
756 (75%)6 (75%)
852 (25%)2 (25%)

Across all 21 studies, recruiting or not: 43% stop at 75 or younger and 14% at 65; 19% take children; 0% are for women only and 0% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

What changed recently

From the registry's own updates since Oct 14, 2026.

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 21 of 21. search them.