Neurofibrosarcoma: all 71 studies
Page 1 of 1. Open to participants first (22), then studies with results posted, then the rest; newest registration first within each.
- Combination of Avutometinib and Defactinib for Treatment of Relapsed, Refractory, Metastatic, or Unresectable Malignant Peripheral Nerve Sheath TumorNot yet recruitingNCT07743554Phase 2
- Safety and Efficacy of BMS-986504 in Unresectable Malignant Peripheral Nerve Sheath TumorRecruitingNCT07549022Phase 1/2
- DoD Award NF230020 Identification of Metabolic Markers and Statistical Prediction of MPNST for Rapid Diagnosis and Assessment of Surgical MarginsRecruitingNCT07298083
- A Study of DEG6498 in Participants With Solid TumorsRecruitingNCT07244835Phase 1
- IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS)RecruitingNCT06849986Phase 2
- Early Phase Study Evaluating MEK and MDM2 Inhibition in Patients With NF1 and MPNSTRecruitingNCT06735820Phase 1/2
- Using CICS-1 and SPM-011 and ［18F］FBPA Commissioned by CICS and Sumitomo Heavy Industries and STELLA PHARMAEnrolling by invitationNCT06603987Phase 1/2
- Evaluation of Chest CT Versus Chest X-Ray for Lung Surveillance After Curative-Intent Resection of High-Risk Truncal-Extremity Soft Tissue SarcomaNot yet recruitingNCT06526897Not applicable
- Neurofibromatosis Type 1 Tumor Early Detection StudyEnrolling by invitationNCT06515860
- MASCT-I Combined With Doxorubicin and Ifosfamide for First-line Treatment of Advanced Soft Tissue SarcomaRecruitingNCT06277154Phase 2
- NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)RecruitingNCT06239272Phase 1/2
- Surveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST)RecruitingNCT06222203
- A Study of Selinexor in People With Wilms Tumors and Other Solid TumorsRecruitingNCT05985161Phase 2
- Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid TumorsRecruitingNCT05732831Phase 1/2
- SPEARHEAD-3 Pediatric StudyRecruitingNCT05642455Phase 1/2
- Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for SarcomasRecruitingNCT05253131Phase 2
- Phase 1 Study of MRTX1719 in Solid Tumors With MTAP DeletionRecruitingNCT05245500Phase 1
- B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)RecruitingNCT04897321Phase 1
- A Study of ASTX727 in People With Malignant Peripheral Nerve Sheath Tumors (MPNST)RecruitingNCT04872543Phase 2
- Metarrestin (ML-246) in Subjects With Metastatic Solid TumorsRecruitingNCT04222413Phase 1
- BLESSED: Expanded Access for DNG64-CAR-V for Advanced Pancreatic Cancer, Sarcoma and Carcinoma of BreastAvailableNCT04091295
- Multi-Institutional Registry for Malignant Peripheral Nerve Sheath TumorsRecruitingNCT03141021
- Tazemetostat in Malignant Peripheral Nerve Sheath TumorsActive, not recruitingNCT04917042Phase 2Results posted
- Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young AdultsTerminatedNCT04530487Phase 2Results posted
- SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath TumorsCompletedNCT03433183Phase 2Results posted
- Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic SarcomaTerminatedNCT02601209Phase 1/2Results posted
- PLX3397 Plus Sirolimus in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath TumorsTerminatedNCT02584647Phase 1/2Results posted
- Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue SarcomaCompletedNCT02584309Phase 2Results posted
- Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial SarcomaCompletedNCT02452554Phase 2Results posted
- Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by SurgeryCompletedNCT02180867Phase 2/3Results posted
- SARC023: Ganetespib and Sirolimus in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors)CompletedNCT02008877Phase 1/2Results posted
- SARC016: Study of Everolimus With Bevacizumab to Treat Refractory Malignant Peripheral Nerve Sheath TumorsCompletedNCT01661283Phase 2Results posted
- Alisertib in Treating Patients With Advanced or Metastatic SarcomaCompletedNCT01653028Phase 2Results posted
- Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory SarcomaCompletedNCT01614795Phase 2Results posted
- Gemcitabine With or Without Pazopanib in Treating Patients With Refractory Soft Tissue SarcomaCompletedNCT01532687Phase 2Results posted
- Gemcitabine and Docetaxel in Combination With Pazopanib (Gem/Doce/Pzb) for the Neoadjuvant Treatment of Soft Tissue Sarcoma (STS)TerminatedNCT01418001Phase 1/2Results posted
- Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic SarcomaCompletedNCT01154452Phase 1/2Results posted
- Sorafenib and Dacarbazine in Soft Tissue SarcomaCompletedNCT00837148Phase 2Results posted
- Trial of Dasatinib in Advanced SarcomasCompletedNCT00464620Phase 2Results posted
- Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue SarcomaCompletedNCT00346164Phase 3Results posted
- Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath TumorsCompletedNCT00304083Phase 2Results posted
- Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent SarcomaCompletedNCT00245102Phase 2Results posted
- Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue SarcomaCompletedNCT00112463Phase 2Results posted
- S0330 Erlotinib in Treating Patients With Unresectable or Metastatic Malignant Peripheral Nerve Sheath TumorCompletedNCT00068367Phase 2Results posted
- Agnostic Therapy in Rare Solid TumorsActive, not recruitingNCT06638931Phase 2
- Multi-parametric Biomarker Development to Predict Malignant Conversion in Patients With Neurofibromatosis Type 1Active, not recruitingNCT05677594
- Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid TumorsTerminatedNCT05275478Phase 1/2
- A Clinical Trial to Evaluate the Safety and Efficacy of AL2846 Capsules in Chinese Patients With Type I NeurofibromatosisTerminatedNCT05011019Phase 1/2
- A Study of Different Dosing Schedules of Selinexor in Sarcoma PatientsCompletedNCT04811196Phase 1
- Incidence of Malignant Peripheral Nerve Sheath Tumor (MPNST) Development in Participants With Neurofibromatosis Type 1 (NF1) Receiving and Not Receiving Medical Therapies Directed at Plexiform Neurofibromas (PN)CompletedNCT04774289
- B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young AdultsActive, not recruitingNCT04483778Phase 1
- Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue SarcomaActive, not recruitingNCT04420975Phase 1
- Hypofractionated Radiotherapy With Hyperthermia in Unresectable or Marginally Resectable Soft Tissue SarcomasStatus unknownNCT03989596Phase 2
- Selinexor in Combination With Ixazomib for the Treatment of Advanced SarcomaWithdrawnNCT03880123Phase 1
- APX005M and Doxorubicin in Advanced SarcomaCompletedNCT03719430Phase 2
- Hypofractionated Radiotherapy With Sequential Chemotherapy in Marginally Resectable Soft Tissue Sarcomas of Extremities or Trunk WallStatus unknownNCT03651375Phase 2
- EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young AdultsActive, not recruitingNCT03618381Phase 1
- A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid TumorsActive, not recruitingNCT03611868Phase 1/2
- Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by SurgeryCompletedNCT03009201Phase 1
- Study of CPI-0610 in Patients With Malignant Peripheral Nerve Sheath TumorsWithdrawnNCT02986919Phase 2
- Nivolumab and Ipilimumab in Treating Patients With Rare TumorsActive, not recruitingNCT02834013Phase 2
- Vaccine Therapy in Treating Patients with Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by SurgeryCompletedNCT02700230Phase 1
- A Study of Pembrolizumab in Patients With Malignant Peripheral Nerve Sheath Tumor (MPNST), Not Eligible for Curative SurgeryTerminatedNCT02691026Phase 2
- Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1CompletedNCT02211768Phase 1
- Whole Body Magnetic Resonance Imaging With Diffusion Weighted Imaging : Potential Role in NeurofibromatosisStatus unknownNCT01777451
- Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue SarcomasCompletedNCT01567046
- HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid TumorsCompletedNCT00931931Phase 1
- Natural History Study of Patients With Neurofibromatosis Type IActive, not recruitingNCT00924196
- Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue SarcomaCompletedNCT00720174Phase 1
- Imatinib Mesylate Treatment of Patients With Malignant Peripheral Nerve Sheath TumorsTerminatedNCT00427583Phase 2/3
- Comparison of Filgrastim and Filgrastim SD/01in Boosting White Cell Counts After Intensive ChemotherapyCompletedNCT00004853Phase 1