An interventional study of Complex Carbohydrate Drink in Same-day Discharge and Length of Stay, sponsored by Hospital for Special Surgery, New York. Recruiting at 1 site in United States. Open to participants aged 18 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-04-13.
Sponsored by Hospital for Special Surgery, New York · Not applicable, Interventional, and Prevention
The purpose of this study is to investigate if the consumption of a complex carbohydrate drink preoperatively, decreases the length of stay and causes for failure to launch in patients undergoing ambulatory total joint arthroplasty.
The way total joint arthroplasty is practiced continues to evolve as CMS removed total hip arthroplasty (THA) from the inpatient-only list and added total knee arthroplasty (TKA) to the ASC Covered Surgical Procedures List (CPL) in 2020. Thus, surgeons must find subtle interventions that improve patient outcomes while minimizing the risk of adverse reactions. Current literature has not assessed the influence of preoperative hydration, using a complex carbohydrate drink, on the same-day discharge rate and causes for failure to launch. Considering variabilities in perioperative fluid management leading to postoperative nausea, vomiting, and dizziness, the investigators seek to reduce the incidence of these events by optimizing patients using a preoperative oral hydration protocol, reducing the length of stay, and improving same-day discharge rates.
644 studies on the registry are indexed under Nausea; 85 are open to participants now.
This study's planned enrollment of 312 is above the median of 96 across 544 interventional studies indexed under Nausea.
Browse Nausea studies →Hospital for Special Surgery, New York is the lead sponsor of 226 studies on the registry; 40 are open to participants now.
Of its 30 completed or terminated interventional studies of FDA-regulated products, 22 (73%) have results posted.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
GFR (glomerular filtration rate) is how much blood the kidneys filter each minute. It is usually estimated from a blood test — eGFR, by formulas such as CKD-EPI or MDRD — and some studies ask for it to be measured directly instead. Usually given in mL/min/1.73 m².
Check the method, the units and the minimum the study states. A value of 90 or above is in the normal-or-high range, but kidney damage can show in other tests too.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
GFR and eGFR (kidney filtering)
GFR (glomerular filtration rate) is how much blood the kidneys filter each minute. It is usually estimated from a blood test — eGFR, by formulas such as CKD-EPI or MDRD — and some studies ask for it to be measured directly instead. Usually given in mL/min/1.73 m².
Check the method, the units and the minimum the study states. A value of 90 or above is in the normal-or-high range, but kidney damage can show in other tests too.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The patients will drink a 400ml drink that contains 50g of complex carbohydrates, 3 hours prior to the surgery. The drink will be given once at the preoperative holding area. Patients are not allowed to eat solid foods after 12am the morning of surgery and can only drink clear fluids up to 3 hours prior to the surgery.
Dietary Supplement: Complex Carbohydrate Drink
These patients will follow normal institutional preoperative fluid management guidelines, this consist of no solid foods after 12am the morning of surgery. Patients are allowed to drink clear liquids (water, clear fruit juices, coffee) from 12am the morning of surgery up to 3 hours prior to the surgery.
Patients will drink a complex carbohydrate drink 3 hours before surgery. Drink to be given at the preoperative holding area.
Length of hospital stay in hours
Length of hospital stay in hours, assess by medical record.
Time frame: From admission to discharge, up to 1 week
Same day discharge rate
Percentage of patients discharged successfully the day of surgery.
Time frame: Through study completion, an average of 3 months.
Number of physical therapy sessions attempted
Number of physical therapy sessions attempted, assess by medical record.
Time frame: From admission to discharge, up to 1 week.
Total distance walked
Total distance walked during physical therapy attempts, assess by medical record.
Time frame: From admission to discharge, up to 1 week.
Number of stairs climbed
Number of stairs climbed during physical therapy attempts, assess by medical record.
Time frame: From admission to discharge, up to 1 week.
Orthostatic hypotension episodes
Orthostatic hypotension episodes during physical therapy attempts, assess by medical record.
Time frame: During physical therapy attempts, from admission to discharge.
HOOS JR Score
This is a 6-item questionnaire that assesses patient-reported hip pain and function. Score ranges from 0-100, with 100 representing the best possible score.
Time frame: The morning of surgery and at the first post-operative visit, up to 4 months post-op.
KOOS JR Score
This is a 6-item questionnaire that assesses patient reported knee pain and function. Score ranges from -100, with 100 representing the best score possible.
Time frame: The morning of surgery and at the first post-operative visit, up to 4 months post-op.
VR-12 Score
The VR-12 is a 12-item self-reported questionnaire that assesses the patient physical and mental quality of life.
Time frame: The morning of surgery and at the first post-operative visit, up to 4 months post-op.
Urine osmolality
Urine osmolality taken preoperatively, assess by medical record.
Time frame: Measured preoperatively the morning of surgery.
Urine specific gravity
Urine specific gravity preoperatively, assess by medical record.
Time frame: Measured preoperatively the morning of surgery.
In-house costs
In-house costs taking into account cost of complex carbohydrate drink vs previously published costs savings per night of stay.
Time frame: From admission to discharge, up to 1 week.
Plan to share: No
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