Mydriasis clinical trials
The registry lists 42 studies for Mydriasis across more than 10 countries. 2 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-06-17.
Status
- Completed
- 32
- Status unknown
- 5
- Terminated
- 3
- Recruiting
- 2
Phase
- Phase 4
- 9
- Phase 3
- 8
- Phase 2
- 5
- Phase 1
- 2
- Early Phase 1
- 1
Where
- United States
- 14
- Belgium
- 6
- Thailand
- 4
- China
- 2
- Egypt
- 2
- Austria
- 2
Who runs them
University Hospital, Antwerp (5) · Eyenovia Inc. (5) · Ocuphire Pharma, Inc. (4) · Khon Kaen University (3) · Denver Health and Hospital Authority (2) · Clinica Oftamologica Zona Sul (1) · Georgetown University (1) · Wenzhou Medical University (1)
Studies
Recruiting first, then most recently updated. Showing 42 of 42 — search for more.
- Comparing Efficacy and Safety of CTO0303 in Pediatric SubjectsRecruitingNCT06609525Phase 2/31 country
- Sutureless Intrascleral Intraocular Lens Fixation and Modified Iris Cerclage PupilloplastyRecruitingNCT05829122Not applicable1 country
- Pharmacodynamics of a Fixed Dose Combination of 0.34% Tropicamide and 2.5% Phenylephrine Hydrochloride, Eye Drop, SolutionCompletedNCT07075224Phase 1/21 country
- Comparison of 4 Methods of Eye Drops for Pupil Dilation in Diabetic PatientsCompletedNCT07495670Not applicable1 country
- Evaluation of Pupil Dilation Speed With the MAP DispenserCompletedNCT04907474Phase 41 country
- The Effect of Eyedrop Size on Pupillary Dilation Using the Nanodropper Bottle AdapterCompletedNCT06689904Not applicable1 country
- Safety and Efficacy of Fixed Combination Phenylephrine-Tropicamide for Pupil DilationCompletedNCT06217796Phase 41 country
- A Study Investigating Whether Low Dose Eyedrops for Pupil Dilation is as Effective and Safe as Standard Dose Eyedrops in Examination for Retinopathy of Prematurity.CompletedNCT06288321Early Phase 11 country
- Efficacy of the Nanodropper Device on Pupillary DilationCompletedNCT05274321Not applicable1 country
- Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced MydriasisCompletedNCT04620213Phase 31 country
- Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis in Pediatric SubjectsCompletedNCT05223478Phase 31 country
- Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis (MIRA-3)CompletedNCT05134974Phase 31 country
- Safety and Efficacy of Ophthalmic Phentolamine Mesylate to Reverse Pharmacologically Induced MydriasisCompletedNCT04024891Phase 21 country
- The Effects of Mydriatic Eye Drops in Retinopathy of Prematurity ExaminationsCompletedNCT058804331 country
- The Use of Nociception Flexion Reflex and Pupillary Dilatation Reflex in ICU Patients.CompletedNCT02916004Not applicable1 country
- Pupillary Dilation Reflex Assessment for Intraoperative Analgesic Titration.CompletedNCT03248908Not applicable1 country
- Study of the Safety, Efficacy and PK of EYN-1601 in Dilation of the PupilCompletedNCT02946125Phase 21 country
- Evaluation of the Pupil Dilation Reflex in Response to Noxious Stimulation in Anaesthetized Children. A Proof of Concept TrialCompletedNCT03449732Not applicable1 country
- Pupil Dilation for Treatment of IFISCompletedNCT03760185Phase 21 country
- Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil DilationCompletedNCT03751631Phase 31 country
- Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil DilationCompletedNCT03751098Phase 31 country
- Stimulation and Validation of the Pupillary Dilation for the Detection of Pain in Analgosedated Patients Under Mechanically Ventilation in Intensive Care UnitStatus unknownNCT04078113Not applicable1 country
- Exploration of Pupil Dilation in Horner's Patients Taking FlomaxTerminatedNCT03615508Phase 41 country
- Comparison Mydriasis by Mydrane With Topical Drop ApplicationCompletedNCT04880928Phase 41 country
- Changes in Vital Signs and Pupil Diameter Related to Pharmacologic Mydriasis in Premature Infants: A Randomized Double Blind Clinical StudyCompletedNCT04838665Phase 4
- Effect of Intracameral Injection of Mydriatic Plus Anaesthetic Combination on Corneal Endothelial Count in PhacoCompletedNCT04396301Phase 31 country
- Optimal Method for Mydriasis in Cataract SurgeryTerminatedNCT02909140Not applicable1 country
- Subconjunctival Atropine and Intracameral Epinephrine for Pupil Dilation in PhacoemulsificationStatus unknownNCT03638726Phase 41 country
- Pupillary Dilation Reflex (PDR) Evaluation During General AnesthesiaCompletedNCT02942316Not applicable1 country
- Pain Assessment by Pupil Dilation Reflex (PDR) and Pupillary Pain Index (PPI) in Response to Noxious Stimulation in Anesthetized AdultsCompletedNCT03140241Not applicable1 country
- Pupil Dilation and Analgesia Nociception IndexCompletedNCT03280238Not applicable1 country
- Intracameral Mydriasis Versus Topical Mydriasis in Cataract SurgeryTerminatedNCT00690222Not applicable1 country
- Lidocaine Usage for Pupil Dilatation (Mydriasis)CompletedNCT01170130Not applicable
- Study to Assess the Influence of Three Different α-antagonists and Placebo on the Extent of Weekly Phenylephrine-induced Mydriasis at Three Different Concentrations of Phenylephrine in Healthy Male VolunteersCompletedNCT02266537Phase 1
- Evaluation of the FIM - a Non Invasive Device for Temporarily and Quick Pupil Dilation (Mydriasis)Status unknownNCT01946828Not applicable1 country
- Methods to Manage Intra-operative Floppy-iris Syndrome and Poor Pupil Dilation in Cataract SurgeryStatus unknownNCT01778959Not applicable1 country
- Study of Intracameral Adrenaline for Pupil Dilation Without Topical Mydriatics in Refractive Cataract SurgeryCompletedNCT01264653Not applicable1 country
- Comparison of Instillation and Packing in Mydriasis for Premature InfantsCompletedNCT00877175Phase 41 country
- Single Dose of 1% Tropicamide and 10% Phenylephrine for Pupillary DilationCompletedNCT00120432Phase 31 country
- 2.5% and 10% Phenylephrine for Mydriasis in Diabetic Patients With Darkly Pigmented IridesCompletedNCT00501878Phase 41 country
- Effect of Anti-inflammatory Topical Prednisolone, Nepafenac and Ketorolac in Intra-operative Mydriasis in FacetectomiesStatus unknownNCT00865540Phase 41 country
- Study on Effective Mydriasis in Premature InfantsCompletedNCT01054027Not applicable1 country