A Phase 3 interventional study of 1% tropicamide and 10% phenylephrine in Eye Diseases, sponsored by Khon Kaen University. Completed at 1 site in Thailand. Open to participants aged 20 Years to 80 Years. Per ClinicalTrials.gov, last updated 2012-03-09.
Sponsored by Khon Kaen University · Phase 3, Interventional, and Treatment
The purpose of this study is to compare the efficacy on pupillary dilation between the single dose versus the three doses of 1% tropicamide with 10% phenylephrine for complete ocular examination.
To the best of the authors' knowledge, there have been no clinical trials using an appropriate regimen for pupillary dilation up until now. Therefore, the authors were interested to find out the most appropriate regimen for complete ocular examination, based on the finding that a pupil diameter of 6 mm or greater is adequate for indirect ophthalmoscopy. The authors hypothesize that a single dose of 1% tropicamide and 10% phenylephrine is adequate to complete the job and are conducting this prospective randomized clinical controlled trial to prove the hypothesis.
388 studies on the registry are indexed under Eye Diseases; 62 are open to participants now.
This study's enrollment of 80 is above the median of 62 across 269 interventional studies indexed under Eye Diseases.
Browse Eye Diseases studies →Khon Kaen University is the lead sponsor of 161 studies on the registry; 24 are open to participants now.
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single dose vs three doses of 1%tropicamide and 10%phenylephrine
Drug: 1% tropicamide and 10% phenylephrine
Drug pages: Tropicamide · Phenylephrine
single dose vs three doses of 1%tropicamide and 10%phenylephrine
horizontal pupil diameter
Time frame: 30 min
systolic blood pressure
Time frame: 30 min
diastolic blood pressure
Time frame: 30 min
heart rate
Time frame: 30 min
adverse drug reaction
Time frame: 30 min
The record gives a start of Dec 2004 and a completion of Jun 2005. It does not say whether these dates are actual or estimated.
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This study is completed, as verified in Mar 2012. You cannot join it, but the record below documents what was studied.
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Studies of the drugs tested here: Tropicamide · Phenylephrine