Radboud University Medical Center: Malaria, Falciparum trials

The registry lists 15 Malaria, Falciparum studies with Radboud University Medical Center as lead sponsor. 0 are open to participants now and 5 have results posted.

Phase 1 5Phase 2 3No phase 10(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Safety and Efficacy of R0.6C VaccineCompletedNCT04862416Phase 1Results posted
• Safety, Tolerability, and Pharmacokinetics and Pharmacodynamics of TB31FCompletedNCT04238689Phase 1Results posted
• Safety and Efficacy of NF135 CPS ImmunizationTerminatedNCT03813108Not applicableResults posted
• Controlled Human Malaria Infection Model for Evaluation of Transmission-blocking Interventions - Study 2CompletedNCT03454048Not applicableResults posted
• Safety and Protective Efficacy of Pb(PfCS@UIS4)CompletedNCT03138096Phase 1/2Results posted
• Safety, Pharmacokinetics, and Plasmodium Falciparum Transmission-reducing Activity of Monoclonal Antibody TB31F in MaliCompletedNCT06413108Phase 1/2
• Non-specific Effects of Vaccination on Mortality and MorbidityStatus unknownNCT03176719
• Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine or Chloroquine/Azithromycin ProphylaxisWithdrawnNCT01783340Phase 1/2
• Re-exposure of Human Volunteers to a Heterologous Strain of P. Falciparum SporozoitesCompletedNCT01660854Not applicable
• Comparison of Three Plasmodium Falciparum Isolates in a Controlled Human Malaria InfectionCompletedNCT01627951Not applicable
• Experimental Human Malaria Infection After Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine ProphylaxisCompletedNCT01236612Not applicable
• Immunization With Different Doses of Plasmodium Falciparum Sporozoites Under Chloroquine ProphylaxisCompletedNCT01218893Not applicable
• Re-exposure of EHMI-8 Human Volunteers to Live Malaria SporozoitesCompletedNCT00757887Not applicable
• Mass-Drug Administration to Reduce Malaria TransmissionCompletedNCT00509015Not applicable
• Study to Investigate the Induction of an Protective Immune Response to MalariaCompletedNCT00442377Not applicable