U.S. Army Medical Research and Development Command: Malaria, Falciparum trials

The registry lists 13 Malaria, Falciparum studies with U.S. Army Medical Research and Development Command as lead sponsor. 0 are open to participants now and 10 have results posted.

Phase 1 11Phase 2 5(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Evaluate the Infectivity Equivalence of Current and New Lots of Plasmodium Falciparum Strain NF54CompletedNCT03882528Phase 1Results posted
• Evaluate the Safety and Efficacy of Plasmodium Falciparum Malaria Protein 010 (FMP010) Administered With Adjuvant AS01BCompletedNCT02458092Phase 1Results posted
• Trial of a Falciparum Malaria Protein (FMP012), E. Coli-expressed PfCelTOS, in Healthy Malaria-Naive AdultsCompletedNCT01540474Phase 1Results posted
• Phase II AMA-1 Malaria Vaccine FMP2.1/AS02A Trial in MaliCompletedNCT00460525Phase 2Results posted
• Phase I Pediatric FMP2.1/AS02A Trial in MaliCompletedNCT00358332Phase 1Results posted
• FMP2.1/AS02A: Rabies Vaccine Malaria-Experienced Adults in Bandiagara, MaliCompletedNCT00349713Phase 1Results posted
• Phase 1 Trial of a Malaria Vaccine in Young Kenyan ChildrenCompletedNCT00317473Phase 1Results posted
• Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of AmericaCompletedNCT00312702Phase 1/2Results posted
• Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of AmericaCompletedNCT00312663Phase 1/2Results posted
• Double-blind, Randomized, Controlled Study of Safety, Immunogenicity and Efficacy of a Candidate Malaria VaccineCompletedNCT00223990Phase 2Results posted
• A Trial For The Study of Falciparum Malaria Protein 014 Administered Via Intramuscular Injection in Healthy AdultsStatus unknownNCT04296279Phase 1
• A Trial For The Study of Falciparum Malaria Protein 013 Administered Via Intramuscular Injection in Healthy AdultsStatus unknownNCT04268420Phase 1
• Safety and Preliminary Efficacy of the Malaria Vaccine Candidates Falciparum Merozoite Protein-1 (FMP1) and SmithKlineBeecham (SKBB) Candidate Malaria Vaccine RTS,SCompletedNCT01556945Phase 1/2