Liver Failure: all 443 studies
Page 1 of 5. Open to participants first (68), then studies with results posted, then the rest; newest registration first within each.
- Role of N-Acetylcysteine in Non-Acetaminophen-Induced Liver FailureRecruitingNCT07765823Not applicable
- CT Volumetry and Hepatic Vascular Deformation Mapping to Predict Post-Hepatectomy Liver FailureRecruitingNCT07727759
- TLI- and ATG-Enabled Minimization Protocol in Liver TransplantationRecruitingNCT07634562Phase 1/2
- Hypothermic Machine Perfusion for Liver Graft PreservationNot yet recruitingNCT07595627Not applicable
- Personalized Two-stage Regional Citrate Anticoagulation for CRRT in Patients With Citrate Metabolism ImpairmentNot yet recruitingNCT07579663Not applicable
- VitaSmart HOPE System: Bridge to HOPE RegistryEnrolling by invitationNCT07578441
- Safety and Tolerability Study of a Novel Bioartificial Liver in Liver Failure and Small-for-Size SyndromeRecruitingNCT07312864Phase 1/2
- National Collaborative Centre for Hepatic Regenerative Medicine (NC-CHRM): Phase I Study on Safety and Efficacy of Mesenchymal Stem-Cell (MSC) Therapy in Non-Viral Acute-on-Chronic Liver Failure (ACLF)Not yet recruitingNCT07131540Phase 1
- CRISPR-Edited HLA Donor Liver Transplant to Reduce RejectionRecruitingNCT07053488Phase 1/2
- Perioperative Use of Amino Acids in Recipients of Orthotopic Liver Transplantation as a Renal Protective FactorNot yet recruitingNCT07004387Not applicable
- Glucocorticoids for Acute Drug Induced Liver Injury With HyperbilirubinemiaRecruitingNCT06922669Not applicable
- Efficacy and Safety of Citrate Anticoagulation in CRRT for Patients With Liver Failure/DysfuncTION, the CAUTION Trial! A Retrospective Study on Etiology of Liver Failure and Their ComplicationsRecruitingNCT06908746
- Safety and Effectiveness of Mesenchymal Stem Cells in Blood Purification for the Treatment of Liver FailureRecruitingNCT06904755Phase 1
- Clinical Study of Pediatric Acute Liver FailureEnrolling by invitationNCT06893042
- Umbilical Cord-derived Mesenchymal Stem Cell Infusion for Treating ACLFNot yet recruitingNCT06884904Phase 2/3
- The Microbiota Augmentation to Reestablish Commensal Organisms (MARCO) TrialRecruitingNCT06871111Phase 1
- Single Cell Landscape of HBV-related Acute-on-chronic Liver Failure PatientsRecruitingNCT06865859
- Study About Hepatic Toxins Kinetic and Evaluation of Organ Damage in Acute on Chronic Liver Failure (ACLF) PatientsRecruitingNCT06837766
- MSC-EVs in Acute/ Acute-on-Chronic Liver Failure After Liver TransplantationNot yet recruitingNCT06825572Phase 1
- Comparison of Efficacy and Safety of Ceftazidime Avibactam Versus Extended Infusions of High Dose Meropenem in Patients of ACLF With Nosocomial Infections.Not yet recruitingNCT06818565Not applicable
- Efficacy and Safety of Continuous Infusion of Terlipressin vs Bolus Terlipressin in ACLF Patients With Acute Esophageal Variceal BleedNot yet recruitingNCT06815770Phase 2/3
- Etiology and Prognostic Analysis of Acute Liver Failure in Chinese ChildrenNot yet recruitingNCT06778941
- Study of Oxidized Albumin in Liver Transplant PatientsNot yet recruitingNCT06772298
- Daily Versus Alternate Day Plasma Exchange in Wilson Disease With Acute Liver Failure in ChildrenNot yet recruitingNCT06698991Not applicable
- Development of a Cognitive Tool for Rapid and Reliable Screening of Minimal Hepatic Encephalopathy: Pilot StudyRecruitingNCT06619106
- Safety and Efficacy of Continuous Infusion of Terlipressin With Norepinephrine Versus Norepinephrine Alone in Improving Outcomes of Acute Kidney Injury in Acute on Chronic Liver Failure With Septic ShockNot yet recruitingNCT06556472Not applicable
- Clinical Retrospective Study Analysis of Postoperative Complications Following HepatectomyRecruitingNCT06532214
- Study on Prognosis of Acute-on-chronic Liver Failure Complicated by Bacterial or Fungal InfectionRecruitingNCT06437067
- To Determine the Predictors of Reversibility for Acute-on-Chronic Liver Failure at 6-months.Not yet recruitingNCT06387160
- To Optimize Therapeutic Procedures of DPMAS in ACLF Patients: a Prospective, Sigle Arm and Multicenter StudyNot yet recruitingNCT06377774
- A Study on Relationship Between Resected Normal Liver Parenchymal Volume（RNLV）and Post-Hepatectomy Liver Failure (PHLF)RecruitingNCT06366048
- Acute hemodynamiC Response To Carvedilol Predicts Survival in ACLF PatientsNot yet recruitingNCT06298656
- An Open-label Randomized Controlled Trial Comparing the Role of Therapeutic Plasma-exchange in Ameliorating Secondary Organ Dysfunctions in Patients With ACLF and Develop Biomarkers of Treatment ResponseNot yet recruitingNCT06276907Not applicable
- A Multicenter Prospective Clinical Cohort Study on the Pathogen Spectrum of Severe Hepatitis (Liver Failure) Complicated With InfectionNot yet recruitingNCT06272071
- Predictive Values of Presepsin Levels in ASciteS in Patients With Chronic Liver FailureRecruitingNCT06224023
- Characteristics and Risk Factors for Invasive Fungal Infection With Acute-on-chronic Hepatitis B Liver FailureNot yet recruitingNCT06190002
- Quantitative MRI and Outcomes of Liver ResectionNot yet recruitingNCT06181318
- Throid Dysfunction in Liver Failure and Its Eddects Upon OutcomeRecruitingNCT06179368
- Phase 1 Hepatic Insufficiency Trial of Methoxyethyl Etomidate HydrochlorideRecruitingNCT06176716Phase 1
- Acute on Chronic Liver Failure in Cirrhotic Patients at Assiut University HospitalsNot yet recruitingNCT06142968
- Individual Nutrition Support in HBV-ACLF Patients at Nutrition RiskRecruitingNCT06128421Not applicable
- Lactate Kinetics as a Predictor of Survival in ACLF With Septic ShockNot yet recruitingNCT06116305
- Prognostic Significance of Acute Change in Liver and Splenic Stiffness in Patients of Acute on Chronic Liver FailureNot yet recruitingNCT06069284
- SALT for Treatment of Patients With Early ACLFNot yet recruitingNCT06069037Not applicable
- To Study the Role of Plasma Von Willebrand Factor Antigen (vWF) to A Disintegrin-like and Metalloproteinase With Thrombospondin Type-1 Motifs 13 (ADAMTS-13) Activity Ratio as a Predictor of Development of Extrahepatic Organ Failure in Acute on Chronic Liver Failure (ACLF) Patients.Not yet recruitingNCT06066814
- Robotic vs. Laparoscopic vs. Open Living Donor HepatectomyEnrolling by invitationNCT06062706
- Usability and Clinical Effectiveness of an Interpretable Deep Learning Framework for Post-Hepatectomy Liver Failure PredictionRecruitingNCT06031818
- Alterations in Coagulation Factor Levels in Patients With End Stage Liver DiseaseNot yet recruitingNCT06014320
- The Safety ,Tolerability and Efficacy Study of HepaCure in Chinese Subjects with Acute-On-Chronic Liver FailureRecruitingNCT05989958Phase 1/2
- Human Umbilical Cord Mesenchymal Stem Cell Transplantation for The Treatment of Acute-on-Chronic Liver FailureRecruitingNCT05985863Phase 1/2
- Identification and Verification of Neutrophil Extracellular Trap Net Related Markers in Acute-on-chronic Liver FailureNot yet recruitingNCT05909319
- The Efficacy and Safety of Rifaximin TreatmentRecruitingNCT05786859Early Phase 1
- Assessment of the Pharmacokinetic Profile of Tacrolimus Medications and Their Relation to Effectiveness and Safety in Liver Transplant PatientsRecruitingNCT05744635
- Registry Study for Optimal Management of Liver Failure in the Chinese PopulationRecruitingNCT05740696
- Empagliflozin in Patients With Cirrhosis and AscitesRecruitingNCT05726032Phase 2
- Point-of-Care Echocardiography to Assess Impact of Dynamic Cardiac Function, Renal and Cardiac Biomarkers in Cirrhosis With Refractory AscitesRecruitingNCT05700708
- Hepatocyte Microbeads for Acute Liver FailureNot yet recruitingNCT05491135Phase 1/2
- Efficacy and Safety of ALSS Treatment for ICIs-LF in Patients With HCCRecruitingNCT05484908Not applicable
- Validation of a Prognostic Score for Steroid Therapy Response in Acute Severe Autoimmune HepatitisNot yet recruitingNCT05473403Not applicable
- Immune Profile, Neuronal Dysfunction, Metabolomics and Ammonia in Therapeutic Response of HE in ACLFRecruitingNCT05421351
- Prognosis of Patients With Acute-on-chronic Liver FailureRecruitingNCT05393453
- Fecal Microbiota Transplantation for Liver FailureRecruitingNCT05170971Not applicable
- Characterization and Pathogenesis of ACLFRecruitingNCT04975490
- May the Risk of PHLF be Predicted With Preoperative Liver Gadoxetate MRIRecruitingNCT04692259Not applicable
- Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver ImpairmentRecruitingNCT04617522Phase 1
- Combination of DPMAS and Low Volume PE for Patients With HBV Related ACLFRecruitingNCT04597164
- Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver DiseaseRecruitingNCT04578301
- Three Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLFRecruitingNCT03920618Not applicable
- Study of Pirtobrutinib (LOXO-305) in Participants With Impaired Liver Function and Healthy ParticipantsCompletedNCT06190691Phase 1Results posted
- Efficacy, Safety and Tolerability of VS-01 in Adult Patients With Acute-on-Chronic Liver Failure and Ascites (UNVEIL-IT)®TerminatedNCT05900050Phase 2Results posted
- Bridge to HOPE: Hypothermic Oxygenated Perfusion Versus Cold Storage Prior to Liver TransplantationCompletedNCT05045794Not applicableResults posted
- Investigate the Influence of Severe Hepatic Impairment on the Pharmacokinetics of Acalabrutinib and Its MetaboliteCompletedNCT03968848Phase 1Results posted
- A Study of Tirzepatide in Participants With Impaired Liver FunctionCompletedNCT03940742Phase 1Results posted
- Single-Dose Pharmacokinetics of MK-3866 in Participants With Hepatic Impairment (MK-3866-006)TerminatedNCT03295266Phase 1Results posted
- BRIDGE Device for Post-operative Pain ControlTerminatedNCT03265249Not applicableResults posted
- Study of Copanlisib in Hepatic or Renal ImpairmentCompletedNCT03172884Phase 1Results posted
- An Open-Label Study Investigating MK-8931 in Participants With Mild and Moderate Hepatic Insufficiency (MK-8931-016)CompletedNCT02910739Phase 1Results posted
- Superior Vena Cava and Its Relationship to Central Venous Pressure Measurements in Liver TransplantationCompletedNCT02818218Results posted
- 13C-Methacetin Breath Test for the Prediction of Outcome in in ALI or ALFCompletedNCT02786836Phase 2/3Results posted
- A Study of the Pharmacokinetics of Uprifosbuvir (MK-3682) and Ruzasvir (MK-8408) in Participants With Moderate and Severe Hepatic Insufficiency (MK-3682-029)CompletedNCT02666352Phase 1Results posted
- Remote Ischemic Conditioning (RIC) in Recipients of Brain Death Donor Livers - A Feasibility and Safety StudyCompletedNCT02635347Not applicableResults posted
- A Randomized Controlled Clinical Trial of Thymoglobulin® After Liver TransplantationCompletedNCT02544113Phase 2Results posted
- Chinese CLIF-C Acute-on-Chronic Liver Disease and Liver Failure StudyCompletedNCT02457637Results posted
- A Study of Abemaciclib in Participants With Varying Degrees of Liver ImpairmentCompletedNCT02387814Phase 1Results posted
- A Study To Describe The Effect Of Impaired Hepatic Function Of The Pharmacokinetics Of PalbociclibCompletedNCT02334800Phase 1Results posted
- Nintedanib in Volunteers With Hepatic Impairment Compared With Healthy VolunteersCompletedNCT02191865Phase 1Results posted
- Study of Efficacy and Safety of Grazoprevir (MK-5172) + Elbasvir (MK-8742) in Chronic Hepatitis C Participants With Child-Pugh (CP)-B Hepatic Insufficiency (MK-5172-059)CompletedNCT02115321Phase 2/3Results posted
- A Study to Investigate the Influence of Hepatic Insufficiency on the Pharmacokinetics of Doravirine (MK-1439) (MK-1439-019)CompletedNCT02089659Phase 1Results posted
- Pharmacokinetic and Pharmacodynamic Study of IDN-6556 in ACLFTerminatedNCT01937130Phase 2Results posted
- Safety and Efficacy of the ELAD System (ELAD) to Treat Acute Liver Failure (ALF)TerminatedNCT01875874Phase 2Results posted
- A Pharmacokinetic Study of Baricitinib in Participants With Liver DiseaseCompletedNCT01870388Phase 1Results posted
- Single Dose Pharmacokinetics of Suboxone Study in Hepatic Impaired SubjectsCompletedNCT01846455Phase 4Results posted
- A Study of Evacetrapib (LY2484595) in Participants With Hepatic (Liver) ImpairmentCompletedNCT01836185Phase 1Results posted
- The Influence of Hepatic Insufficiency on the Pharmacokinetics of Elbasvir (MK-8742) (MK-8742-009)CompletedNCT01797536Phase 1Results posted
- A Single Dose Study of LY2605541 in Participants With Liver ImpairmentCompletedNCT01751399Phase 1Results posted
- A Single-Dose Study of the Pharmacokinetics of Vibegron (MK-4618) in Adults With Hepatic Insufficiency (MK-4618-013)CompletedNCT01737684Phase 1Results posted
- Sofosbuvir and Ribavirin in Patients With Chronic HCV With Cirrhosis and Portal Hypertension With or Without Liver DecompensationCompletedNCT01687257Phase 2Results posted
- Safety Study of Ornithine Phenylacetate to Treat Patients With Acute Liver Failure/Severe Acute Liver InjuryCompletedNCT01548690Phase 2Results posted
- Assessment of Pharmacokinetics of Single Dose Odanacatib (MK-0822) in Participants With Moderate Hepatic Insufficiency (MK-0822-070)CompletedNCT01512693Phase 1Results posted
- A Study of LY2140023 in Hepatically-Impaired ParticipantsCompletedNCT01475136Phase 1Results posted