Liver Failure: all 443 studies
Page 2 of 5. Open to participants first (68), then studies with results posted, then the rest; newest registration first within each.
- Study to Investigate the Influence of Hepatic Insufficiency on the Pharmacokinetics of Grazoprevir (MK-5172-013)CompletedNCT01390428Phase 1Results posted
- Pharmacokinetics of Empagliflozin (BI 10773) in Patients With Impaired Liver FunctionCompletedNCT01111318Phase 1Results posted
- Pharmacokinetics of Suvorexant in Participants With Hepatic Insufficiency (MK-4305-017)CompletedNCT01043926Phase 1Results posted
- Human Fetal Liver Cell Transplantation in Chronic Liver FailureCompletedNCT01013194Phase 1/2Results posted
- A Study Investigating the Influence of Hepatic Insufficiency on the Pharmacokinetics of Vaniprevir (MK-7009-005)CompletedNCT01010906Phase 1Results posted
- Intravenous Milk Thistle (Silibinin-Legalon) for Hepatic Failure Induced by Amatoxin/Amanita Mushroom PoisoningTerminatedNCT00915681Phase 2Results posted
- Study of N-Acetylcysteine in Acute Liver Failure (ALF)TerminatedNCT00896025Phase 4Results posted
- Study to Evaluate if the Drug Vasopressin Protects the Kidneys for Patients Undergoing Liver TransplantCompletedNCT00886262Not applicableResults posted
- Single-Dose Pharmacokinetics of BMS-790052 in Participants With Hepatic ImpairmentCompletedNCT00859053Phase 1Results posted
- Pharmacokinetics of LCP-Tacro™ Once Daily and Prograf® Twice A Day in Adult De Novo Liver Transplant PatientsCompletedNCT00772148Phase 2Results posted
- Evaluation Of Hepatic Impairment On AG-013736 PharmacokineticsCompletedNCT00692341Phase 1Results posted
- A Phase I/II Safety and Tolerability Dose Escalation Study of Autologous Stem Cells to Patients With Liver InsufficiencyCompletedNCT00655707Phase 1/2Results posted
- Pharmacokinetics of LCP-Tacro in Stable Liver Transplant PatientsCompletedNCT00608244Phase 2Results posted
- N-acetylcysteine in Non-Acetaminophen Pediatric Acute Liver FailureCompletedNCT00248625Phase 3Results posted
- Adult Stem Cell Therapy in Liver InsufficiencyCompletedNCT00147043Not applicableResults posted
- Gradual Withdrawal of Immune System Suppressing Drugs in Patients Receiving a Liver TransplantCompletedNCT00135694Phase 2Results posted
- Bidirectional Cohort Study of a Prognosis Model for Acute-on-chronic Liver FailureActive, not recruitingNCT07548190
- Ex Vivo Perfusion of Gene-Edited Porcine Livers in Patients With Severe Hepatic FailureActive, not recruitingNCT07519005Early Phase 1
- Single-Cell and Spatial Transcriptomics Analysis of Steatotic Donor Liver Susceptibility to Post-Transplant InjuryCompletedNCT07362745
- Phase I Trial of QH-1A Hybrid Bio-Artificial Liver With Ex Vivo Blood-Purifying MSCs in Acute-on-Chronic Liver FailureActive, not recruitingNCT06996392Phase 1
- Role of N-Acetylcysteine in Non-Acetaminophen-Induced Acute Liver FailureActive, not recruitingNCT06872372Not applicable
- Plasma Proteomics Study of End-Stage Liver Disease Patients Based on Olink TechnologyActive, not recruitingNCT06865898
- A Comparative Analysis of Preoperative Liver Volumetry in Living Donor Liver TransplantationCompletedNCT06865612
- Continuous Renal Replacement Therapy (CRRT) in Surgery Room During Orthotopic Liver Transplantation (OLT)CompletedNCT06844435Not applicable
- Biliary Complication Rates in Living Donor Liver Transplantation: a Retrospective Comparative Study of Stent Versus Non-Stent GroupsActive, not recruitingNCT06767553
- Clinical Trial of FCN-437c Capsule in Patients With Hepatic InsufficiencyCompletedNCT06620731Phase 1
- Maternal And Fetal Outcomes in Pregnant Women With Liver DiseaseCompletedNCT06594237
- A Pharmacokinetic Study of Simufilam in Subjects With Impaired Hepatic FunctionCompletedNCT06390410Phase 1
- Modified Thoracoabdominal Nerve Plane Block In Living Liver DonorsCompletedNCT06300372Not applicable
- Correlation of Blood Gene Expression (TruGraf Liver) With Liver Biopsy in Pediatric Liver Transplant RecipientsTerminatedNCT06263114
- Aerobic Capacity Muscle Strength and Health Related Quality of Life in Children With Chronic Liver DiseaseCompletedNCT06240832Not applicable
- A Non-interventional, Post-Marketing Study to Describe Outcome of Nitisinone Treatment in HT-1 PatientsWithdrawnNCT06227429
- Plasma Exchange for Amanita Toxin-induced Acute Liver FailureCompletedNCT06187220
- Evaluation of HDL Subfraction Changes and HDL-Associated Enzymes in Liver Failure Patients and Healthy DonorsCompletedNCT05958420
- The Safety and Efficacy of MSC-EVs in Acute/Acute-on-Chronic Liver FailureWithdrawnNCT05940610Phase 1/2
- A Study of LY3437943 in Participants With Impaired and Normal Liver FunctionCompletedNCT05916560Phase 1
- MSC-EV in Acute-on-Chronic Liver Failure After Liver TransplantationWithdrawnNCT05881668Phase 1
- Endoscopic Ultrasound Guided Liver Biopsy and Portal Pressure RegistryWithdrawnNCT05817994
- S100A8/A9 and Innate Immunity in Liver DiseaseStatus unknownNCT05793983
- A Machine Learning Architecture to Predict Post-Hepatectomy Liver Failure Using Liver Regeneration Biomarkers and Time-Phased DataCompletedNCT05779098
- Efficacy of L-ornithine L-aspartate and Therapeutic Plasma Exchange Versus Plasma Exchange Alone in Lowering Ammonia and Improving Outcomes in Pediatric Acute Liver Failure.Status unknownNCT05778461Not applicable
- Characterization of Metabolomic Fingerprints in Patients With Acute Liver Failure and Acute-on-chronic Liver Failure With Hepatic EncephalopathyWithdrawnNCT05772585
- Albumin Infusion in Inpatients With Decompensated CirrhosisStatus unknownNCT05719051
- Intravenous BCAA for HE in ACLF (BCAA-HE-ACLF)CompletedNCT05700695Phase 1
- To Compare Relaxed Rotational Thromboelastometry Cut-offs With Standard Cut-offs for Guiding Blood Product Use Before Invasive Procedures in Cirrhosis and Acute on Chronic Liver Failure PatientsStatus unknownNCT05672589Not applicable
- The Role of Skin Microbiota in Hepatic or Renal PruritusStatus unknownNCT05604469
- Gd-EOB-DTPA-enhanced T1 Map for Predicting Postoperative Liver FailureCompletedNCT05592106
- Role of Bilirubin Molecular Species in Hepatic Encephalopathy and Acute-on-chronic Liver FailureStatus unknownNCT05566548
- Evaluation of the Efficacy of Fomepizole in the Treatment of Acetaminophen OverdoseTerminatedNCT05517668Phase 2
- Pharmacokinetic Study of Continuous Infusion of Remazolam in Mechanically Ventilated Patients in ICUStatus unknownNCT05480787Phase 4
- The Renal Safety of Tenofovir Alafenamide in HBV-related Acute-on-chronic Liver Failure: Real-World StudyCompletedNCT05453448Not applicable
- 20% Albumin vs. Balanced Salt Solution as Resuscitation Fluid in Cirrhosis With Sepsis Induced HypotensionStatus unknownNCT05441878Phase 4
- Intravenous Ketamine Infusion on Postoperative Analgesia of Living Liver DonorsStatus unknownNCT05441150Phase 4
- Point-of-Care Echocardiography to Assess Impact of Dynamic Cardiac Function, Renal and Cardiac Biomarkers in Cirrhosis With Hepatorenal Syndrome-Acute Kidney InjuryStatus unknownNCT05434286
- Evaluation of Cardiac Function in Acutely Decompensated CirrhosisActive, not recruitingNCT05413083
- Efficacy and Economic Evaluation of Nonbiological Artificial Liver Therapy in Acute-on-chronic Hepatitis B Liver Failure.CompletedNCT05392673Not applicable
- Efficacy and Safety of Avatrombopag for Treating TCP in HBV-ACLF Patients Receiving ALSS TreatmentStatus unknownNCT05382013Phase 4
- HepaRAS Trial: Changes in Hepatectomy Risk Assessment When Using Mebrofenin HIDAWithdrawnNCT05280990Not applicable
- Safety and Clinical Activity of QEL-001 in A2-mismatch Liver Transplant PatientsActive, not recruitingNCT05234190Phase 1/2
- Acute Hemodynamic Response to Carvedilol in Predicting Survival in Acute on Chronic Liver Failure Patients - A Pilot Study.Status unknownNCT05180292Not applicable
- CytoSorb® in Patients With Acute on Chronic Liver FailureWithdrawnNCT05131230
- Evaluation of Long Haul COVID-19 and Vaccine Immunogenicity in Patients With Liver DiseaseCompletedNCT05107271
- Intravenous NAC Use in ACLF PatientsStatus unknownNCT05089981Not applicable
- Transplantation for EASL-CLIF and APASL ACLF Patients: a Retrospective Cohort StudyStatus unknownNCT05036031
- Cytokine Adsorption in Acute-on-chronic Liver FailureStatus unknownNCT05019352Not applicable
- Pharmacokinetics Of Jaktinib In Subjects With Hepatic Impairment And Normal Hepatic FunctionCompletedNCT04993404Phase 1
- To Evaluate the Safety and Efficacy of Preemptive Administration of Continuous Renal Replacement Therapy in Patients With Acute Liver Failure With Cerebral EdemaStatus unknownNCT04991259Not applicable
- Utility of Liver and Splenic Stiffness in Predicting Esophageal Varices in Patients With Acute on Chronic Liver FailureCompletedNCT04983108
- Incidence and Predictors of Bleeding Diathesis Development Due to DIC in Cirrhosis and ACLF Patients Undergoing CRRTStatus unknownNCT04960163
- Citrate Pharmacokinetics in Critically Ill Liver Failure Patients Receiving CRRTCompletedNCT04959110Not applicable
- Avatrombopag in Patients With End-stage Liver Disease and ThrombocytopeniaStatus unknownNCT04906083Phase 4
- A Study to Evaluate the Effect of Hepatic Insufficiency on the Pharmacokinetics (PK) of ACP-196CompletedNCT04867941Phase 1
- TReatment for ImmUne Mediated PathopHysiologyActive, not recruitingNCT04862221Phase 2
- Safety of UC-MSC Transfusion for ACLF PatientsStatus unknownNCT04822922Phase 2
- Acute-On-Chronic Liver Failure In Cirrhotic PatientsCompletedNCT04790435
- Mortality, Morbidity and Risk Factors of Liver RetransplantationCompletedNCT04789213
- Thromboelastography Guides a Multicentre Cluster Controlled Study of Plasma Exchange for Hepatitis B Associated Acute-on-chronic Liver FailureStatus unknownNCT04747106Not applicable
- Intraoperative Hemodynamic Management and Postoperative Outcomes in Liver TransplantationCompletedNCT04732689
- Hepatectomy Risk Assessment With Functional Magnetic Resonance ImagingStatus unknownNCT04705194
- Patients' Outcome With Severe or Fulminant Hepatic Insufficiency, Hospitalized in the Public Hospitals of ParisStatus unknownNCT04658407
- Role of Fecal Microbiota in Predicting Graft Rejection and Sepsis Among Recipients of Living Donor Liver Transplant in First Year.Status unknownNCT04621812
- Biliary Anastomosis Using Surgical Loupe Versus Microscope in Living Donor Liver TransplantationCompletedNCT04618692Not applicable
- Pharmacokinetic Study of Icenticaftor in Participants With Hepatic ImpairmentCompletedNCT04587622Phase 1
- Ammonia Metabolism Assessed by Ammonia InfusionStatus unknownNCT04585672Not applicable
- SELF-BREATHE RCT for Chronic BreathlessnessCompletedNCT04574050Not applicable
- One Way to Diagnose Hepatic Insufficiency the First Postoperative Day After Resection: Prospective Cohort StudyCompletedNCT04570800
- Platelet Transfusion in Acute-on Chronic Liver FailureStatus unknownNCT04564651Not applicable
- Assessment of Remnant Liver Function in ALPPS by Gd-EOB-DTPA Enhanced MRIStatus unknownNCT04559451
- NOninVasive Intracranial prEssure From Transcranial doppLer Ultrasound Development of a Comprehensive Database of Multimodality Monitoring Signals for Brain-Injured PatientsCompletedNCT04548596
- The Early Strength Training Program in Post-transplant Liver CasesCompletedNCT04546048Not applicable
- Risk Factors for Acute Kidney Injury in Critically Ill Patients With Acute-on-Chronic Liver FailureStatus unknownNCT04525625
- Perioperative Lactate Kinetics in Patient Undergoing Major Liver SurgeryCompletedNCT04512014
- CytoSorb in Patients With Liver FailureCompletedNCT04511507
- Efficacy of Albumin Plus Midodrine v/s Albumin Alone in Reducing Incidence of Paracentesis Induced Circulatory Dysfunctions in ACLF Patients.Status unknownNCT04474262Not applicable
- Effects of the SGLT2 Inhibitor Empagliflozin in Patients With Euvolemic and Hypervolemic HyponatremiaCompletedNCT04447911Phase 4
- Efficacy of Addition of Fecal Microbiota Transplant (FMT) and Plasma Exchange to Tenofovir in Comparison to Monotherapy With Tenofovir in ACLF-HBVStatus unknownNCT04431375Not applicable
- Efficacy of Early Terlipressin Plus Albumin Therapy in Comparison to Standard Treatment for HRS-AKI in Acute-on-chronic Liver Failure.CompletedNCT04416282Not applicable
- Bowel Colonization With Multi-drug Resistant Bacterial Species in Hospitalized Patients With acute-on Chronic Liver Failure (ACLF), and Its Relationship With Extra-intestinal Infectious Events and Short-term Outcomes.CompletedNCT04383106
- Meals MATTER: A Trial of Medically Tailored Meals 2 Weeks vs. 4 Weeks Post Hospital DischargeCompletedNCT04351880Not applicable
- Lipid Emulsions and Liver Function - Results After 5 Years.CompletedNCT04347902Phase 4