Lentigo clinical trials
The registry lists 28 studies for Lentigo across more than 10 countries. 2 are recruiting or about to start. 27 of them are mainly about Lentigo (how this is decided). Per ClinicalTrials.gov, last updated 2026-09-14. Counting its narrower condition Peutz-Jeghers Syndrome too: 50 studies, 10 open.
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Who runs them
Cryonove Pharma (5) · Cutera Inc. (3) · Cryobeauty (2) · National Taiwan University Hospital (2) · Cosmetique Active International (1) · Sciton (1) · Panion & BF Biotech Inc. (1) · Pontificia Universidad Catolica de Chile (1)
What is being tested here
Drugs under test in Lentigo studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Lidocaine | 0 | 0 | 1 |
| Trichloroacetic Acid | 0 | 0 | 1 |
| Glycolic acid | 0 | 0 | 1 |
| Tretinoin | 0 | 0 | 1 |
Who these studies take
No Lentigo study is recruiting now.
Across all 28 studies, recruiting or not: 57% stop at 75 or younger and 25% at 65; 7% take children; 14% are for women only and 0% for men only; 50% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Lentigo studies take
Of 11 interventional studies with no phase under Lentigo, half reached primary completion within 2 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 2 mo1–13 · 11 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 28 of 28. search them.
- CLINICAL INVESTIGATION TO EVALUATE THE EFFICACY AND SAFETY OF EPILADY PROTOTYPE DEVICE FOLLOWED BY APPLICATION OF A TOPICAL FORMULA ON DEPIGMENTATION OF LENTIGO SPOTSNot yet recruitingNCT07239726Not applicable1 country
- Evaluation of the Tolerance (Main Objective) and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post-inflammatory Hyperpigmentation) on the FaceNot yet recruitingNCT06305897Not applicable
- Relevance of Imiquimod as Neo-adjuvant Treatment to Reduce Excision Size and the Risk of Intralesional Excision in Lentigo Malignant of the FaceCompletedNCT01720407Phase 31 country
- The Effect of Topical Anesthetics on Patients' Pain and Operative Experience During Treatment With QSwitched LaserCompletedNCT02427724Early Phase 11 country
- Safety and Efficacy of High-Intensity Macrofocused Ultrasound for Solar Lentigo in Chinese PopulationCompletedNCT062886071 country
- Evaluation of Broadband Light Treatment for Solar LentiginesCompletedNCT06363240Not applicable1 country
- TCA 15% Chemical Peel for Improvement in Hand LentiginesCompletedNCT05471947Phase 41 country
- Interventional, Monocentric, Double-blind Randomized Category 2b Study Evaluating the Evaluation of the Tolerance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post -Inflammatory Hyperpigmentation (Pih)) on the FaceCompletedNCT06361251Not applicable1 country
- Advanced Harmonic Generation Microscopy for Treatment Assessment of Cutaneous Pigmentary DisorderCompletedNCT03578315Not applicable1 country
- Comparison of 3 in Vivo Microscopic Imaging Techniques for the Diagnosis of Pigmented TumorsCompletedNCT060461441 country
- A Single-Center 2-Arm Study for Lentigines on the HandsCompletedNCT02763072Not applicable1 country
- Tolerance and Mode of Administration of Cyto-selective Cryotherapy Treatments in Face Brown Spots: Proof of ConceptCompletedNCT05203263Not applicable1 country
- Tolerance of Cyto-selective Difluoroethane-based CryotherapyCompletedNCT05322668Not applicable1 country
- Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots PROOF OF CONCEPTCompletedNCT05014321Not applicable1 country
- Evaluate the Efficacy and Safety of Brightening Micro-needle Patch on Facial Solar LentiginesCompletedNCT04583852Not applicable1 country
- Study for the RevLite Laser System for Facial Solar LentiginesCompletedNCT02110108Not applicable1 country
- A Fixed Triple Combination Cream for Solar Lentigines Associated to CryotherapyCompletedNCT01778179Not applicable
- Efficacy and Tolerance of D-pigment Versus Moisturizer in Hands' Lentigo Lesions With or Without Laser TherapyCompletedNCT03457246Not applicable
- Laser Removal of Age (Sun) Spots on HandsCompletedNCT01885871Not applicable1 country
- Assessment of CRYOBEAUTY MAINS ET DECOLLETE Versus Liquid Nitrogen Cryotherapy, in the Treatment of Solar LentiginesCompletedNCT03225729Not applicable1 country
- Clinical Evaluation of the Performance of a Difluoroethane-based Cyto-selective Cryotherapy to Treat Dark Spots on the Hand in 30 Volunteers.CompletedNCT03157427Not applicable1 country
- A Prospective Multi-Center Study Using Laser for the Treatment of Melasma and Lentigines in Asian SkinCompletedNCT02385994Not applicable2 countries
- Topical Corticosteroids on the Incidence of Postinflammatory Hyperpigmentation After QsNdYAG LaserCompletedNCT02492373Not applicable1 country
- Comparative Study of the Therapy of Solar Lentigines With a Q-switched Rubin Laser Versus a Bleaching CreamCompletedNCT02153697Not applicable1 country
- Clinical, Histological and Biochemical Characterization of Hyperpigmented LesionStatus unknownNCT011366291 country
- Evaluate the Lightening Effect of the Whitening Cosmetic Product BEX-2011Status unknownNCT01249469Not applicable1 country
- Solar Lentigines Treatment With the Triple Combination CreamCompletedNCT00975312Phase 21 country
- Side Effects of Q-Switched Ruby Laser for the Treatment of Lentigines in Light and Dark Skin TypesCompletedNCT00386204Phase 21 country