Peutz-Jeghers Syndrome clinical trials
The registry lists 22 studies for Peutz-Jeghers Syndrome across 6 countries. 8 are recruiting or about to start. 8 of them are mainly about Peutz-Jeghers Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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A study of drug A after surgery for early breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
Johns Hopkins University (2) · Associazione Italiana per lo Studio del Pancreas (1) · University of Pittsburgh (1) · Icahn School of Medicine at Mount Sinai (1) · Ohio State University Comprehensive Cancer Center (1) · White Plains Hospital (1) · Haramaya Unversity (1) · Shandong University (1)
What is being tested here
Drugs under test in Peutz-Jeghers Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Celecoxib | 1 | 0 | 1 |
| Everolimus | 0 | 0 | 2 |
| Secretin human | 0 | 0 | 1 |
| Sirolimus | 0 | 0 | 1 |
Drug classes tested here mTOR inhibitors 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
- Jul 2027The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics · H. Lee Moffitt Cancer Center and Research Institute
Who these studies take
Of the 7 Peutz-Jeghers Syndrome studies recruiting now, 6 (86%) set no upper age limit and 0 (0%) stop at 75 or younger. 3 (43%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (43%) | 3 (43%) |
| 18 | 7 (100%) | 7 (100%) |
| 30 | 7 (100%) | 7 (100%) |
| 40 | 7 (100%) | 7 (100%) |
| 50 | 7 (100%) | 7 (100%) |
| 65 | 7 (100%) | 7 (100%) |
| 75 | 7 (100%) | 7 (100%) |
| 85 | 6 (86%) | 6 (86%) |
Across all 22 studies, recruiting or not: 14% stop at 75 or younger and 5% at 65; 41% take children; 0% are for women only and 5% for men only; 18% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting1
- Chinese Multicenter Registry for Peutz-Jeghers SyndromeNov 12, 2026NCT07889596
Newly registered1
- Chinese Multicenter Registry for Peutz-Jeghers SyndromeOct 22, 2026NCT07889596
Studies
Recruiting first, then most recently updated. Showing 22 of 22. search them.
- Chinese Multicenter Registry for Peutz-Jeghers SyndromeRecruitingNCT078895961 country
- The Cancer of the Pancreas Screening-5 CAPS5)StudyRecruitingNCT02000089Phase 31 country
- Familial Investigations of Childhood Cancer PredispositionRecruitingNCT030502681 country
- Pancreas Registry and High Risk RegistryRecruitingNCT027754611 country
- Celecoxib for Prevention of Progression in Peutz-Jeghers SyndromeRecruitingNCT06722534Not applicable1 country
- Inherited Cancer Early Diagnosis (ICED) StudyRecruitingNCT061633651 country
- Cold Snare Polypectomy for Small Bowel Polyps in Patients With Peutz-Jeghers SyndromeNot yet recruitingNCT06001476Phase 41 country
- Registry of Subjects at Risk of Pancreatic CancerRecruitingNCT040951951 country
- Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney ComplexCompletedNCT000014521 country
- Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian CancerCompletedNCT000402221 country
- The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel TherapeuticsActive, not recruitingNCT056925961 country
- Pancreatic Cancer Early Detection ProgramCompletedNCT022063601 country
- Pilot Study of mTOR Inhibitor Therapy in Peutz-Jeghers SyndromeTerminatedNCT00811590Phase 21 country
- Poorly Differentiated Adenocarcinoma of the Jejunum in a Patient With Peutz-Jeghers Syndrome: A Case ReportCompletedNCT062424571 country
- Cancer of the Pancreas Screening Study (CAPS 3)CompletedNCT004389061 country
- Pancreatic Cancer Screening of High-Risk Individuals in ArkansasWithdrawnNCT02309632Not applicable1 country
- Efficacy of Rapamycin (Sirolimus) in the Treatment of Peutz-Jeghers SyndromeStatus unknownNCT03781050Phase 41 country
- Study of Accurate Diagnosis and Treatment of Peutz-Jeghers SyndromeStatus unknownNCT03806075Not applicable1 country
- Hereditary Colorectal and Associated Tumor Registry StudyCompletedNCT006336071 country
- Single Incision Laparoscopic Surgery in Treating Patients With Colorectal DiseaseCompletedNCT01656746Not applicable1 country
- Study of Everolimus in the Treatment of Advanced Malignancies in Patients With Peutz-Jeghers SyndromeWithdrawnNCT01178151Phase 21 country
- Secretin (ChiRhoStim) Pancreas Perfusion for Pancreatic AdenocarcinomaTerminatedNCT00587132Phase 1/21 country