An interventional study of topical 0.05% Clobetasol propionate ointment and Q switched Nd:YAG laser 532 nm in Lentigines and Post Inflammatory Hyperpigmentation, sponsored by Mahidol University. Completed at 1 site in Thailand. Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-06-01.
Sponsored by Mahidol University · Not applicable, Interventional, and Treatment
To investigate the benefit of the application of topical high potency steroid on the incidence of post inflammatory hyperpigmentation after laser treatment.
28 studies on the registry are indexed under Lentigo; 2 are open to participants now.
This study's enrollment of 21 is below the median of 30 across 25 interventional studies indexed under Lentigo.
Browse Lentigo studies →Mahidol University is the lead sponsor of 747 studies on the registry; 119 are open to participants now.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Cancer (malignancy)
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Immunosuppression
A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.
Read whether the line is about a condition or about medicines, and which medicines and doses it means.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before lentigines' treatment with Qs Nd:YAG 532 nm laser, topical 0.05% Clobetasol propionate ointment was applied 2 days on the lesion. Then applied 2 days after the treatment.
Drug: topical 0.05% Clobetasol propionate ointment · Device: Q switched Nd:YAG laser 532 nm
Controlled side. Applied topical 0.05% Clobetasol propionate ointment only 2 days after the laser treatment
Drug: topical 0.05% Clobetasol propionate ointment · Device: Q switched Nd:YAG laser 532 nm
Apply only on the treated area twice a day as mentions
Treatment of facial lentigines. The energy using depends on the endpoint of immediate whitening of the lesions.
The incidence of post inflammatory hyperpigmentation
By investigator's observation.
Time frame: 2 weeks
Side effects of topical steroid
By investigators' observation of telangiectasia, erythema or atrophy.
Time frame: Follow-up 2, 3, 4, 8, 12 and 24 weeks after the last treatment
The patients satisfaction
By using Quartile grading scale of improvement; 0 = not improve, 1= 1-25% improvement, 2 = 26-50% improvement, 3 = 51-75% improvement and 4 = 76-100% improvement
Time frame: Follow-up 4, 8, 12 and 24 weeks after the last treatment
The record gives a start of Feb 2015, a primary completion of May 2016 and a completion of May 2016. It does not say whether these dates are actual or estimated.
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This study is completed, as verified in May 2016. You cannot join it, but the record below documents what was studied.
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