A Phase 4 interventional study of 15% Trichloroacetic acid + 3% glycolic acid in Photoaging and Lentigo, sponsored by Main Line Center for Laser Surgery. Completed at 1 site in United States. Open to participants aged 22 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-03-17.
Sponsored by Main Line Center for Laser Surgery · Phase 4, Interventional, and Treatment
This study will evaluate the efficacy of the a 15% trichloroacetic acid + 3% glycolic acid peel combination for treatment of lentigines on the hands. This peel combination is sold over the counter. Patients will receive 3 treatments (spaced 4 weeks).
This clinical investigation is a prospective study consisting of a screening visit, 3 treatment visits, and 1 follow-up visit. Baseline and post-treatment photos will be graded and compared.
A total of 20 patients will be recruited. Following informed consent and screening, subjects' dorsal hands will be photographed.
Patients will receive 3 treatments with the 15% TCA + 3% glycolic acid peel every 4-6 weeks on the dorsal hands. Post-treatment, patients will be instructed to apply Aquaphor to the treated area twice daily for 5 days. Patients' hands will be photographed at each visit.
Four to six weeks after their final treatment, subjects will return for photography.
28 studies on the registry are indexed under Lentigo; 2 are open to participants now.
This study's enrollment of 20 is below the median of 30 across 25 interventional studies indexed under Lentigo.
Browse Lentigo studies →Main Line Center for Laser Surgery is the lead sponsor of 5 studies on the registry; none are open to participants now.
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Exclusion Criteria:
Treatment of hand lentigines with 15% trichloroacetic acid + 3% glycolic acid
Drug: 15% Trichloroacetic acid + 3% glycolic acid
Drug pages: Trichloroacetic Acid · Glycolic acid
Treatment of the hand with an over-the-counter chemical peel containing 15% trichloroacetic acid + 3% glycolic acid
Also known as: 15% TCA + 3% GA
Improvement in hand lentigines on a 5-point scale
Photos will be graded on a 5 point scale (0=no change, 1=1-25% change, 2=26-50% change, 3=51-75% change, 4=76-100% change)
Time frame: 4-6 weeks after last treatment
Improvement in hand lentigines using the Global Aesthetic Improvement Scale
The GAIS is a validated scale assessing overall change after aesthetic procedures
Time frame: 4-6 weeks after last treatment
Plan to share: No
This study is completed, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.
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Studies of the drugs tested here: Trichloroacetic Acid · Glycolic acid
Main Line Center for Laser Surgery