Language Disorders clinical trials
The registry lists 84 studies for Language Disorders across more than 10 countries. 18 are recruiting or about to start. 21 of them are mainly about Language Disorders (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05. Counting its 10 narrower conditions too, such as Aphasia: 875 studies, 257 open.
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Who runs them
Riphah International University (3) · Southwest Autism Research & Resource Center (3) · National Institute on Deafness and Other Communication Disorders (NIDCD) (2) · Oregon Health and Science University (2) · University of Central Florida (2) · University of Houston (2) · US Department of Veterans Affairs (2) · Vanderbilt University (2)
What is being tested here
Drugs under test in Language Disorders studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Levoleucovorin calcium | 1 | 0 | 2 |
| Levoleucovorin | 1 | 0 | 2 |
| VX-745 | 0 | 0 | 1 |
| Leucovorin | 0 | 0 | 1 |
| Rotigotine | 0 | 0 | 1 |
| Omega-3 fatty acid | 0 | 0 | 1 |
| Ecopipam | 0 | 1 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Mar 2027Neurophysiological Mechanisms of Language Comprehension · University of Alabama at Birmingham
- Jun 2027Evaluating a Targeted Selective Speech, Language, and Communication Intervention at Scale - Protocol for the 'Happy Talk' Cluster Randomised Controlled Trial. · University College Cork
- Jun 2027Enhancing Language Function in Aphasia · University of Arizona
- Nov 2027CRacking the HEterogeneity of Social Outcome Through Neuropsychophysiological Profiles · IRCCS San Raffaele
- Nov 2027Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia · Stephanie Grasso
Who these studies take
Of the 14 Language Disorders studies recruiting now, 3 (21%) set no upper age limit and 7 (50%) stop at 75 or younger. 7 (50%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 9 (64%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (7%) | 1 (7%) |
| 18 | 5 (36%) | 5 (36%) |
| 30 | 8 (57%) | 8 (57%) |
| 40 | 8 (57%) | 8 (57%) |
| 50 | 8 (57%) | 8 (57%) |
| 65 | 7 (50%) | 7 (50%) |
| 75 | 7 (50%) | 7 (50%) |
| 85 | 5 (36%) | 5 (36%) |
Across all 84 studies, recruiting or not: 61% stop at 75 or younger and 57% at 65; 57% take children; 0% are for women only and 0% for men only; 38% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Language Disorders studies take
Of 36 interventional studies with no phase under Language Disorders, half reached primary completion within 27 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 27 mo9–54 · 36 studies | — | 24 mo9–56 · 35 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Results posted1
- Predicting Rehabilitation Outcomes in Bilingual Aphasia Using Computational ModelingNov 5, 2026NCT02916524
Studies
Recruiting first, then most recently updated. Showing 50 of 84. Browse all 84 → or search them.
- Neurophysiological Mechanisms of Language ComprehensionRecruitingNCT05283265Not applicable1 country
- Transcranial Alternating Current Stimulation (tACS) in AphasiaRecruitingNCT04375722Not applicable1 country
- Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive AphasiaRecruitingNCT05741853Not applicable2 countries
- Treatment of Social and Language Deficits With Leucovorin for Young Children With AutismRecruitingNCT04060030Phase 21 country
- Development and Validation of Language and Communication Assessment ScalesRecruitingNCT075185761 country
- Study of Language Disorders and Interactions Between Mnesic Capabilities and Semantic Competencies in Patients With PsychosisRecruitingNCT06036316Not applicable1 country
- Chinese-Specific Speech Imagery Coding Using High-Density ECoGRecruitingNCT07460037Not applicable1 country
- Magnetoencephalography in Psychosis ProgramEnrolling by invitationNCT069788811 country
- DIALOG: Understanding Disorganisation: A Language-focused Global Initiative in PsychosisNot yet recruitingNCT069784651 country
- Measuring Aided Language DevelopmentRecruitingNCT06512168Not applicable1 country
- Language Outcomes, Mechanisms, and Trajectories in Adults With and Without Developmental Language DisorderRecruitingNCT068986711 country
- CRacking the HEterogeneity of Social Outcome Through Neuropsychophysiological ProfilesNot yet recruitingNCT06869616
- Emergent Bilinguals: Child Language Proficiency and Language of TreatmentRecruitingNCT06866223Not applicable1 country
- The Relationship Between Child Language Proficiency and Language of Treatment on the Outcomes of Bilingual Children with Developmental Language DisorderRecruitingNCT06085300Not applicable1 country
- Enhancing Language Function in AphasiaRecruitingNCT05443633Not applicable1 country
- Evaluating a Targeted Selective Speech, Language, and Communication Intervention at Scale - Protocol for the 'Happy Talk' Cluster Randomised Controlled Trial.Not yet recruitingNCT06460090Not applicable1 country
- Early Augmentative and Alternative Communication (AAC) Intervention Delivered Via Hybrid TelehealthRecruitingNCT05743439Not applicable1 country
- Clinical Evaluation and Intervention of Developmental Behavioral Diseases Based on Multicenter Cohort Study(CEIDBDBMCS)RecruitingNCT06025890Not applicable1 country
- Pilot Evaluation of the Developed Syntactic-Semantic Visual Configuration Intervention for Children With Language ImpairmentCompletedNCT07786545Not applicable1 country
- Predicting Rehabilitation Outcomes in Bilingual Aphasia Using Computational ModelingCompletedNCT02916524Not applicable1 country
- Retrieval-Based Word Learning in Developmental Language Disorder During Book Reading IICompletedNCT07048392Not applicable1 country
- CNKSR2 Natural History StudyActive, not recruitingNCT065002601 country
- Clinical Study of Neflamapimod in Patients With Primary Progressive AphasiaActive, not recruitingNCT07033481Phase 22 countries
- Impact of Group Participation on Adults With AphasiaActive, not recruitingNCT05520528Not applicable1 country
- Recasting or Book Reading by Parents or CliniciansCompletedNCT05099328Not applicable1 country
- Effectiveness of Intensive Aphasia Therapy Under Routine Clinical ConditionsCompletedNCT01540383Not applicable1 country
- Leucovorin for the Treatment of Language Impairment in Children With Autism Spectrum DisorderActive, not recruitingNCT02839915Phase 21 country
- Early Treatment of Language Impairment in Young Children With Autism Spectrum Disorder With Leucovorin CalciumActive, not recruitingNCT04060017Phase 21 country
- Training Grammar With MeaningCompletedNCT06250101Not applicable1 country
- Retrieval Practice for Word Learning for Deaf and Hard of Hearing ChildrenCompletedNCT05512000Not applicable1 country
- Efficacy of Let's Know! First GradeCompletedNCT06945289Not applicable1 country
- Characterization of Auditory Processing Involved in the Encoding of Speech SoundsCompletedNCT02574299Not applicable1 country
- Determining Optimal Treatment Intensity for Children With Language ImpairmentCompletedNCT04501536Not applicable1 country
- Parent Child Interaction Therapy vs Conventional Parent Led Therapy in Down SyndromeCompletedNCT07128810Not applicable1 country
- Modulating Intensity and Dosage of Aphasia ScriptsCompletedNCT04138940Not applicable1 country
- Shared Interactive Book Reading in Preschool Children with Neurodevelopmental Disorders: Effects on Language Development and Reading HabitsActive, not recruitingNCT068529891 country
- Reducing Anxiety Problems Among Children Indicated to Have Developmental Language DisorderCompletedNCT05552365Not applicable1 country
- Dopaminergic Therapy for Frontotemporal Dementia PatientsCompletedNCT04937452Phase 21 country
- Smart Computing Models, Sensors, and Early Diagnostic Speech and Language Deficiencies Indicators in Child CommunicationCompletedNCT06633874Not applicable1 country
- Inner Speech and Naming Treatment for Individuals with AphasiaCompletedNCT05980897Not applicable1 country
- MyoVoice to Restore Natural, Hands-free Communication to Individuals With Vocal ImpairmentsCompletedNCT04762043Not applicable1 country
- Building Sentences With Preschoolers Who Use AACCompletedNCT03538925Phase 21 country
- Efficacy of a Digital Therapeutic for People With Dysarthria After StrokeCompletedNCT05146765Not applicable1 country
- rTMS and Multi-Modality Aphasia Therapy for Post-Stroke AphasiaCompletedNCT04901156Not applicable1 country
- Impact of Neuromodulation on Language Impairments in Stroke PatientsCompletedNCT03699930Not applicable1 country
- Prevalence of Oral Disorders in Children in ENT PathologiesStatus unknownNCT05909787Not applicable
- Assessment of Language Disorders in Multiple Sclerosis PatientsCompletedNCT04465084Not applicable1 country
- Speeded Anomia Treatment in Chronic Post-stroke AphasiaStatus unknownNCT05512884Not applicable1 country
- Efficiency of Speech and Language Intervention on Achievement of Children With Developmental Language DisorderCompletedNCT049263111 country
- EEG Changes in Pediatrics With Language Dysfunction Evaluation of Sleep EEG Changes in Paediatric Patients With Language Dysfunction: A Follow up Study. EEG Changes in Pediatrics With Language DysfunctionCompletedNCT05487521Phase 31 country