An interventional study of Adductor canal block with IPACK and 4 in 1 block in Knee Surgeries, Total Ankle Arthroplasty and Anterior Cruciate Ligament (ACL) Tear, sponsored by Zagazig University. Completed at 1 site in Egypt. Open to participants aged 21 Years to 64 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-17.
Sponsored by Zagazig University · Not applicable, Interventional, and Treatment
This randomized interventional study compares the analgesic efficacy of Adductor Canal Block combined with Infiltration of the Posterior Capsule of the Knee (IPCAK) versus the 4-in-1 block technique in patients undergoing knee surgery. Twenty-four patients were randomly allocated into two equal groups. The primary objective is to compare postoperative pain scores and analgesic requirements. Secondary outcomes include time to first rescue analgesia, total analgesic consumption, motor function preservation, and block-related complications.
Effective postoperative pain control following knee surgery is essential for early mobilization, rehabilitation, and patient satisfaction. Several regional anesthesia techniques have been developed to provide analgesia while preserving quadriceps muscle strength. Adductor Canal Block combined with Infiltration of the Posterior Capsule of the Knee (IPCAK) has been proposed as a motor-sparing technique that provides effective anterior and posterior knee analgesia. The 4-in-1 block is another ultrasound-guided regional anesthesia technique designed to provide comprehensive analgesia for knee surgery.
This prospective randomized interventional study enrolled 24 patients undergoing knee surgery. Participants were randomly assigned to receive either Adductor Canal Block with IPCAK or the 4-in-1 block. Postoperative pain scores, time to first rescue analgesia, total analgesic consumption, motor function, patient satisfaction, and complications were evaluated and compared between the two groups
174 studies on the registry are indexed under Lacerations; 43 are open to participants now.
This study's enrollment of 24 is below the median of 65 across 128 interventional studies indexed under Lacerations.
Browse Lacerations studies →Zagazig University is the lead sponsor of 459 studies on the registry; 77 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Exclusion Criteria:
Current severe psychiatric disease, alcoholism or drug dependence. Subjects with history previous knee surgery, osteoarthritis, malformation or tumors (including Baker's cyst), which could alter the normal anatomy of the popliteal fossa
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Patients receive ultrasound-guided Adductor Canal Block combined with Infiltration of the Posterior Capsule of the Knee (IPCAK) for postoperative analgesia after knee surgery
Procedure: Adductor canal block with IPACK
Patients receive ultrasound-guided 4-in-1 block for postoperative analgesia after knee surgery.
Procedure: 4 in 1 block
Ultrasound-guided Adductor Canal Block combined with IPCAK block
Ultrasound-guided 4-in-1 block technique.
Postoperative pain intensity measured by Visual Analog Scale (VAS)
Postoperative pain will be assessed using the Visual Analog Scale (VAS) at rest and during movement at predetermined postoperative time points
Time frame: 24 hours after surgery
Total opioid consumption
Total rescue opioid analgesic consumption during the first 24 postoperative hours
Time frame: First 24 hours after surgery
Time to first rescue analgesia
Time from completion of surgery to the first request for rescue analgesia
Time frame: Within 24 hours after surgery
Patient satisfaction with postoperative analgesia
Patient satisfaction score regarding postoperative pain management
Time frame: 24 hours after surgery
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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