An interventional study of Intervention and Placebo in Bloating, Digestive Discomfort and Irritable Bowel Syndrome (IBS), sponsored by JS Health & Vitamins. Completed at 1 site in United States. Open to female participants aged 18 Years to 45 Years. Per ClinicalTrials.gov, last updated 2026-10-29.
Sponsored by JS Health & Vitamins · Not applicable, Interventional, and Treatment
This is a double-blind, randomized, placebo-controlled trial evaluating the efficacy of JSHealth's Debloat \& Detox supplement, used alone or in combination with their Probiotics supplement, on gut and digestive health and function in 60 female participants aged 18-45 with self-reported bloating and digestive discomfort.
Participants will be randomly assigned to either the intervention or placebo group for eight weeks. During the first four weeks, intervention participants will take the Debloat \& Detox supplement and placebo participants will take a corresponding placebo. During weeks five through eight, intervention participants will add the Probiotic supplement and placebo participants will add a probiotic placebo. Outcomes will be assessed via study-specific questionnaires and abdominal circumference measurements at Baseline, Day 1 (after first use), and at the end of Weeks 2, 4, 6, and 8.
1,116 studies on the registry are indexed under Irritable Bowel Syndrome; 208 are open to participants now.
This study's enrollment of 60 is below the median of 70 across 896 interventional studies indexed under Irritable Bowel Syndrome.
Browse Irritable Bowel Syndrome studies →This is the only study on the registry with JS Health & Vitamins as lead sponsor.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A planned gap after a treatment, so that its effects can lessen before the study treatment or a study assessment. Ask the study team and the doctor who prescribed it before changing any medicine.
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Washout period
A planned gap after a treatment, so that its effects can lessen before the study treatment or a study assessment. Ask the study team and the doctor who prescribed it before changing any medicine.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Hypersensitivity
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Dietary Supplement: Intervention
Dietary Supplement: Placebo
Participants take the JSHealth Debloat \& Detox supplement (two tablets once daily after the first meal) during Weeks 1-4, then add the JSHealth Probiotic supplement (one tablet once daily after the first meal) during Weeks 5-8.
Participants take a placebo matching the Debloat \& Detox supplement during Weeks 1-4, then add a placebo matching the Probiotic supplement during Weeks 5-8.
Change in digestive and gut health symptoms including reduced stomach bloating and fluid retention
Assessed via study-specific self-reported questionnaires measuring perceived reduction in stomach bloating and fluid retention
Time frame: Baseline, Day 1 (after first use), Week 2, and Week 4
Change in relief from symptoms of IBS
Assessed via study-specific self-reported questionnaires measuring relief from IBS symptoms, flatulence, and digestive discomfort
Time frame: Baseline, Day 1 (after first use), Week 2, and Week 4
Change in relief from symptoms of flatulence
Assessed via study-specific self-reported questionnaires measuring relief from IBS symptoms, flatulence, and digestive discomfort
Time frame: Baseline, Day 1 (after first use), Week 2, and Week 4
Change in relief from symptoms of digestive discomfort
Assessed via study-specific self-reported questionnaires measuring relief from IBS symptoms, flatulence, and digestive discomfort
Time frame: Baseline, Day 1 (after first use), Week 2, and Week 4
Time to symptom relief
Assessed via study-specific self-reported questionnaires measuring time to onset of digestive symptom relief
Time frame: Baseline, Day 1 (after first use), Week 2, and Week 4
Change in abdominal circumference
At-home independent waist/abdominal circumference measurement using a provided tape measure
Time frame: Baseline, Week 2, Week 4, Week 6, and Week 8
Change in bloating and IBS symptoms with combination supplementation
Assessed via study-specific self-reported questionnaires measuring noticeably less bloating and IBS symptoms when Debloat \& Detox is used in combination with the Probiotic supplement
Time frame: Baseline, Week 6, and Week 8
Change in relief from constipation
Assessed via study-specific self-reported questionnaires measuring relief from constipation when using both supplements in combination
Time frame: Baseline, Week 6, and Week 8
Change in overall gut and digestive function
Assessed via study-specific self-reported questionnaires measuring overall improvement in gut and digestive function with combination supplementation
Time frame: Baseline, Week 6, and Week 8
Ran from Feb 2026 to primary completion in Apr 2026, 2 months.
Of 52 industry-sponsored interventional studies with no phase under Irritable Bowel Syndrome, half reached primary completion within 13 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 28. This study's 2 months is below that.
Counting every sponsor, half of 357 studies reached it within 19 months; a quarter within 9 and three quarters within 38.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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