Hypoxia-Ischemia, Brain: all 261 studies

Page 2 of 3. Open to participants first (94), then studies with results posted, then the rest; newest registration first within each.

• Tissue Oxygenation During Treatment of Infant Congenital Heart DefectsCompletedNCT03941015Results posted
• Caffeine for Hypoxic-Ischemic EncephalopathyCompletedNCT03913221Phase 1Results posted
• Stimulant Therapy Targeted to Individualized Connectivity Maps to Promote ReACTivation of ConsciousnessActive, not recruitingNCT03814356Phase 1Results posted
• A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Participants With Developmental and/or Epileptic EncephalopathiesCompletedNCT03650452Phase 2Results posted
• CEUS Evaluation of Hypoxic Ischemic InjuryCompletedNCT03549520Phase 3Results posted
• Holding, Stress, and Bonding During Therapeutic HypothermiaCompletedNCT03079284Not applicableResults posted
• A Multi-site Study of Autologous Cord Blood Cells for Hypoxic Ischemic EncephalopathyCompletedNCT02612155Phase 2Results posted
• Neonatal Erythropoietin And Therapeutic Hypothermia Outcomes in Newborn Brain Injury (NEATO)CompletedNCT01913340Phase 1/2Results posted
• Safety of Clonidine in Infants With Hypoxic Ischemic Encephalopathy During Therapeutic HypothermiaCompletedNCT01862250Phase 1/2Results posted
• Preemie Hypothermia for Neonatal EncephalopathyCompletedNCT01793129Not applicableResults posted
• Topiramate in Neonates Receiving Whole Body Cooling for Hypoxic Ischemic EncephalopathyTerminatedNCT01765218Phase 1/2Results posted
• Prospective Research in Infants With Mild EncephalopathyCompletedNCT01747863Results posted
• California Transport Cooling TrialCompletedNCT01683383Not applicableResults posted
• Darbe Administration in Newborns Undergoing Cooling for EncephalopathyCompletedNCT01471015Phase 1/2Results posted
• Optimizing (Longer, Deeper) Cooling for Neonatal Hypoxic-Ischemic Encephalopathy(HIE)TerminatedNCT01192776Not applicableResults posted
• The TOBY Children StudyCompletedNCT01092637Results posted
• Neuroprotective Effects of Hypothermia Combined With Inhaled Xenon Following Perinatal AsphyxiaCompletedNCT00934700Not applicableResults posted
• Safety and Efficacy of Hypothermia to Treat Neonatal Hypoxic-Ischemic EncephalopathyCompletedNCT00890409Phase 3Results posted
• Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-IH [In Hospital] TrialCompletedNCT00880087Not applicableResults posted
• Pilot Study of Head Cooling in Preterm Infants With Hypoxic Ischemic EncephalopathyCompletedNCT00620711Phase 1Results posted
• Late Hypothermia for Hypoxic-Ischemic EncephalopathyCompletedNCT00614744Not applicableResults posted
• Renal and Cerebral NIRS and Early Acute Kidney Injury in Cooled Neonates With Birth AsphyxiaCompletedNCT07743099
• Foot Reflexology in Neonates With Hypoxic-Ischemic EncephalopathyCompletedNCT07549789Not applicable
• The Effect of Maternal Scent and Knitted Octopus Application on Pain in Infants Diagnosed With Neonatal Asphyxia and Receiving Therapeutic Hypothermia TreatmentCompletedNCT07526233Not applicable
• An Observational Study of the NeuroBell EEG MonitorCompletedNCT07508670
• EFFICACY OF MELATONIN IN MANAGEMENT OF HYPOXIC ISCHEMIC ENCEPHALOPATHY (HIE) IN NEONATESActive, not recruitingNCT07305350Phase 2
• Multiomics Profiling of CSF in Cardiac Arrest SurvivorsActive, not recruitingNCT07090577
• Cell-Based Therapy for White Matter Repair in Periventricular LeukomalaciaWithdrawnNCT06985303Early Phase 1
• Cord Blood S100B Protein Levels in Neonates Following Intrauterine Transfusions for HDFN-Associated Fetal AnemiaTerminatedNCT06984445
• Metabolic Monitoring During Therapeutic Hypothermia (Cooling) for Hypoxic Ischaemic EncephalopathyCompletedNCT06932354Not applicable
• Cord Blood S100B Protein Concentration in Neonates With Fetal Growth RestrictionCompletedNCT06893926
• ANS Function in HIE Infants Treated With Therapeutic HypothermiaCompletedNCT06730490
• Monitoring After Cardiac Arrest: Electroencephalogram and Cerebral Oximetry in Predicting OutcomeCompletedNCT06460480
• Dose Optimization of Caffeine for HIEActive, not recruitingNCT06448780Phase 1
• PEDI-REAVASC Resonance Imaging of Infants With Hypoxic Ischemic Encephalopathy After Hypothermia Treatment.Active, not recruitingNCT06370624Not applicable
• The Effects of Minimal Enteral Nutrition on Mesenteric Blood Flow and Oxygenation in Neonates With HIECompletedNCT06344286Not applicable
• Umbilical Cord Milking Versus Immediate Cord Clamping in Full Term Neonates (≥ 37 Weeks) Requiring ResuscitationCompletedNCT06090968Not applicable
• Identification of a Pool of miRNA to Improve Early Management of Perinatal Asphyxia and Hypoxic Ischemic EncephalopathyCompletedNCT05986994
• Hypothermia's Effect on Hepatitis B VaccinationCompletedNCT05787899
• Maternal and Neonatal Risk Factors of HIEStatus unknownNCT05749458
• Effect of Non-nutritive Sucking on Transition to Oral Feeding in Infants With AsphyxiaCompletedNCT05687708Not applicable
• Metformin Treatment in Infants After Perinatal Brain InjuryTerminatedNCT05590676Phase 1
• Investigating Cerebral Oxygenation in the NewbornActive, not recruitingNCT05588960
• Whole-Body Hypothermia for Neonates With Hypoxic-Ischemic Encephalopathy(HIE)WithdrawnNCT05581927Not applicable
• Effects of a Physical Therapy Intervention on Motor Delay in Infants Admitted to a Neonatal Intensive Care UnitActive, not recruitingNCT05568264Not applicable
• Continous Renal Replacement Therapy With the CARPEDIEM® in a French National Cohort of 25 Neonates and Small InfantsCompletedNCT05495607
• Florida Cerebrovascular Disease Biorepository and Genomics CenterActive, not recruitingNCT05491980
• Neuropsychological Rehabilitation Over the InternetCompletedNCT05413733Not applicable
• RIC in HIE: A Safety and Feasibility TrialCompletedNCT05379218Not applicable
• Neonatal Seizure Registry, GEnetics of Post-Neonatal EpilepsyActive, not recruitingNCT05361070
• PK and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic HypothermiaWithdrawnNCT05295784Phase 1
• Babies in Glasses; a Feasibility Study.Status unknownNCT05048550Not applicable
• Normobaric Hyperoxia Combined with Endovascular Therapy in Patients with Stroke Within 6 Hours of Onset：longterm OutcomeCompletedNCT05039697Not applicable
• Multisite Tissue Oxygenation Guided Perioperative Care in Cardiac SurgeryCompletedNCT04896736Not applicable
• THE ROLE OF CARDIAC MARKERS IN HYPOXIC ISCHEMIC ENCEPHALOPATHY IN LONG-TERM NEURODEVELOPMENTAL FOLLOW UPStatus unknownNCT04766541
• Biomarkers And Neurological Outcome in Neonates 2Status unknownNCT04714775
• Asphyxia Associated Metabolite Biomarker Investigation 2Status unknownNCT04714502
• NVD in Hypothermic HIE NeonatesCompletedNCT04643821Early Phase 1
• Transcutaneous Carbon Dioxide Monitoring in Neonates Receiving Therapeutic Hypothermia for Neonatal EncephalopathyActive, not recruitingNCT04603547
• EEG Slow Wave Activity in Hypoxic Brain InjuryCompletedNCT04506788
• Antenatal and Intrapartum Risk Factors Associated With Neonatal Hypoxic Ischemic EncephalopathyStatus unknownNCT04364932
• Neonatal Seizure Registry - Developmental Functional EValuationCompletedNCT04337697
• Evaluation of the "Pupillary Pain Index" in Neurological Prognosis After Cardiac ArrestStatus unknownNCT04336930
• Prognostic Value of Arterial Spin Labeling Brain Perfusion MRI in Term Neonates With Hypoxic-ischemic EncephalopathyCompletedNCT04325230Not applicable
• Diet Induced Ketosis for Brain Injury - A Feasibility StudyCompletedNCT04308577Not applicable
• The Clinical Trial of CL2020 Cells for Neonatal Hypoxic Ischemic EncephalopathyCompletedNCT04261335Phase 1
• Influence of Cooling Duration on Efficacy in Cardiac Arrest PatientsCompletedNCT04217551Not applicable
• TIME Study: Therapeutic Hypothermia for Infants With Mild EncephalopathyStatus unknownNCT04176471Not applicable
• Sub-study of the NEURODOC Project : Neurophysiological Evaluation of a Routine Care Open Label tDCS SessionCompletedNCT04035655Not applicable
• Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing AbnormalitiesWithdrawnNCT03996317Not applicable
• Continuous, Non-invasive Monitoring of Intraoperative Cerebral Perfusion and Oxidative Metabolism (CPOM)CompletedNCT03907904
• The Impact of Holding on Stress and Bonding in Mother-Infant Pairs During Therapeutic HypothermiaCompletedNCT03837717Not applicable
• The Ability of NIRS to Predict Brain Injury in Hypoxic Ischemic EncephalopathyTerminatedNCT03835039
• Use of Melatonin for Neuroprotection in Asphyxiated NewbornsStatus unknownNCT03806816Not applicable
• Protecting Brains and Saving Futures - the PBSF ProtocolStatus unknownNCT03786497
• Becoming Children With Perinatal Anoxo-Ischemic Encephalopathy Without Indication of Therapeutic HypothermiaCompletedNCT03744481
• Rapid Reversal of CNS-Depressant Drug Effect Prior to Brain Death DeterminationWithdrawnNCT03743805Early Phase 1
• Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries Developmental Follow UpActive, not recruitingNCT03682042Not applicable
• Umbilical Cord Milking in Neonates Who Are Depressed at Birth-Developmental Follow Up (MIDAB-FU)WithdrawnNCT03681314Not applicable
• Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced KountriesCompletedNCT03657394Not applicable
• Bedside Optical Retinal Assessment of Hypoxic Ischemic Encephalopathy in InfantsCompletedNCT03640494
• Study of hCT-MSC in Newborn Infants With Moderate or Severe HIECompletedNCT03635450Phase 1
• Neonatal Hypoxic Ischemic Encephalopathy:Early Diagnosis and Management of ComorbiditiesStatus unknownNCT03550612
• Neuropsychological Outcome After Cardiac ArrestCompletedNCT03543371
• Evaluation of Long-Term Gait Development in Infants With Neonatal Encephalopathy Using Infant TreadmillTerminatedNCT03534466Not applicable
• Evaluation of Long-term Neurodevelopment in Neonatal Encephalopathy by Infant TreadmillWithdrawnNCT03527498Not applicable
• Propofol-induced EEG Changes in Hypoxic Brain InjuryCompletedNCT03485781
• Feasibility and Safety of Umbilical Cord Blood Transfusion in the Treatment of Neonatal Cerebral Ischemia and AnemiaStatus unknownNCT03352310Phase 1
• Combined Intracerebral and Jugular Bulb MicrodialysisCompletedNCT03314779
• Quantitative Assessment of Sucking for Early Diagnosis of Brain Injury in Infants at High RiskTerminatedNCT03246243
• Implementation of Neuro Lung Protective VentilationActive, not recruitingNCT03243539Not applicable
• Role of Citicoline in Treatment of Newborns With Hypoxic Ischemic EncephalopathyStatus unknownNCT03181646Phase 3
• Heart Beat Variability in Neonatal EncephalopathyActive, not recruitingNCT03179553
• Erythropoietin in Management of Neonatal Hypoxic Ischemic EncephalopathyStatus unknownNCT03163589Phase 3
• Role of Umbilical Cord Milking in the Management of Hypoxic-ischemic Encephalopathy in NeonatesStatus unknownNCT03123081Not applicable
• Out-of-hospital Cardiac Arrest (OHCA) BiomarkersCompletedNCT03112486
• MRI of Neonate With HIE Before and During the Moderate HypothermiaStatus unknownNCT03079492
• PAEAN - Erythropoietin for Hypoxic Ischaemic Encephalopathy in NewbornsCompletedNCT03079167Phase 3
• Intra-operative Feed Back on Traction Force During Vacuum Extraction: Safe Vacuum Extraction AllianceCompletedNCT03071783Not applicable
• Cerebral Oxymetry and Neurological Outcome in Therapeutic HypothermiaCompletedNCT03024021

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