Hypothermia clinical trials
The registry lists 449 studies for Hypothermia across more than 10 countries. 54 are recruiting or about to start. 276 of them are mainly about Hypothermia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-02.
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Who runs them
University of Alabama at Birmingham (12) · The Cleveland Clinic (7) · Haukeland University Hospital (7) · University Hospital Schleswig-Holstein (7) · University Hospital Heidelberg (6) · Medical University of Vienna (6) · Assistance Publique - Hôpitaux de Paris (5) · William Marsh Rice University (5)
What is being tested here
Drugs under test in Hypothermia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Dec 2026Study of the Prevalence of Postoperative Hypothermia in Adults Undergoing Non-Cardiac Surgery in Spanish Post-Anesthesia Care Units · Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
- Dec 2026Assessing Local Hypothermia and Endovascular Recanalization for Acute Stroke With a Large Core Infarction · First Affiliated Hospital of Wannan Medical College
- Dec 2026Role of Hypothermia in Endovascular Stroke Thrombectomy · Xinqiao Hospital of Chongqing
- Feb 2027Effect of Prewarming Duration on Blood Flow After Colon Resection Surgery · Çiğdem Ünal Kantekin
- Jul 2027Temperature Optimization in Afebrile Septic PatienTs · Matt Harmon
- Jul 2027Quantification of Brain and Kidney Perfusion Before, During, and After Hypothermia Treatment in Neonates With Perinatal Asphyxia Using Contrast-enhanced Ultrasound · University of Erlangen-Nürnberg Medical School
- Sep 2027Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part I · University of Alabama at Birmingham
- Sep 2027Systemic Hypothermia in Acute Cervical Spinal Cord Injury · University of Miami
- Sep 2027Core Temperature in Patients With OHCA · Azienda Sanitaria dell'Alto Adige
- Oct 2027Resistive Versus Forced-Air Warming for Prevention of Perioperative Hypothermia · Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Who these studies take
Of the 27 Hypothermia studies recruiting now, 13 (48%) set no upper age limit and 12 (44%) stop at 75 or younger. 12 (44%) take children under 18. 1 (4%) are for women only and 0 (0%) for men only; 6 (22%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 6 (22%) | 6 (22%) |
| 18 | 20 (74%) | 19 (70%) |
| 30 | 20 (74%) | 19 (70%) |
| 40 | 19 (70%) | 19 (70%) |
| 50 | 19 (70%) | 19 (70%) |
| 65 | 19 (70%) | 19 (70%) |
| 75 | 15 (56%) | 15 (56%) |
| 85 | 14 (52%) | 14 (52%) |
Across all 449 studies, recruiting or not: 38% stop at 75 or younger and 32% at 65; 30% take children; 8% are for women only and 3% for men only; 25% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hypothermia studies take
Of 135 interventional studies with no phase under Hypothermia, half reached primary completion within 16 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 16 mo6–36 · 135 studies | — | 16 mo6–36 · 132 studies |
| Observational | 12 mo4–50 · 48 studies | — | 12 mo4–50 · 47 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
- Role of Hypothermia in Endovascular Stroke ThrombectomyOct 29, 2026NCT06109376
Newly registered1
- Resistive Versus Forced-Air Warming for Prevention of Perioperative HypothermiaNov 2, 2026NCT07909252
Studies
Recruiting first, then most recently updated. Showing 50 of 449. Browse all 449 → or search them.
- Resistive Versus Forced-Air Warming for Prevention of Perioperative HypothermiaNot yet recruitingNCT07909252Not applicable1 country
- Role of Hypothermia in Endovascular Stroke ThrombectomyRecruitingNCT06109376Not applicable1 country
- Stimulation-Temperature-Oxygen-Positioning Multimodal Neuroprotection for Acute Ischemic Stroke (STOP)Not yet recruitingNCT07840794Not applicable
- Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)RecruitingNCT05376267Not applicable5 countries
- Effect Of Acupressure On Hypothermıa And Shıverıng After Cesarean SectıonRecruitingNCT07864376Not applicable1 country
- Continuous Monitoring of Body Temperature in Neonates During Therapeutic HypothermiaRecruitingNCT077568921 country
- Effect of Prewarming Duration on Blood Flow After Colon Resection SurgeryNot yet recruitingNCT07857538Not applicable1 country
- Optimizing the Paracetamol Dose for Prevention of Post-Spinal Shivering in Lower Limb Orthopedic SurgeriesNot yet recruitingNCT07855575Phase 4
- Efficacy of Intravenous Midazolam-Ketamine Combination Versus Placebo for Prevention of Post-Spinal Shivering in Elective Cesarean SectionNot yet recruitingNCT07855523Phase 4
- Effect of Preoperative Intranasal Dexmedetomidine on Incidence of Intraoperative Shivering in Patients Undergoing Cesarean Section Under Spinal AnesthesiaNot yet recruitingNCT07855536Phase 4
- Study of the Prevalence of Postoperative Hypothermia in Adults Undergoing Non-Cardiac Surgery in Spanish Post-Anesthesia Care UnitsEnrolling by invitationNCT078397281 country
- Temperature Optimization in Afebrile Septic PatienTsRecruitingNCT07831057Not applicable1 country
- Prehospital Resuscitation Intranasal Cooling Effectiveness Survival Study 2RecruitingNCT06025123Not applicable8 countries
- Systemic Hypothermia in Acute Cervical Spinal Cord InjuryRecruitingNCT02991690Not applicable1 country
- Core Temperature in Patients With OHCARecruitingNCT049767121 country
- Targeted Temperature Management on Delayed Neurocognitive Recovery in Older Patients After Major Cancer SurgeryNot yet recruitingNCT07655687Not applicable1 country
- ESOTIP-TEE: Defining an Easy Landmark to Guide Correct Esophageal Probe Placement With Transesophageal EchocardiographyRecruitingNCT075747361 country
- Effect of Thermoregulation Bundle Applied at Birth on Neonatal Physiological Parameters and BreastfeedingRecruitingNCT07453264Not applicable1 country
- Assessing Local Hypothermia and Endovascular Recanalization for Acute Stroke With a Large Core InfarctionNot yet recruitingNCT07232082Not applicable
- Pulmonary Function by Litter PositionEnrolling by invitationNCT07219290Not applicable1 country
- Arch-Clamping Technique Under Mild Hypothermia in Treating With Acute Type A Aortic DissectionRecruitingNCT07150559Not applicable1 country
- Long Term Follow-up of Cardiac Arrest Survivors Exposed to Ultra-rapid CoolingRecruitingNCT070283721 country
- Perioperative Hypothermia and Sevoflurane Consumption in Elderly PatientsNot yet recruitingNCT07467681
- Prehospital Use of Forced Air WarmingEnrolling by invitationNCT07450092Not applicable1 country
- The Clinical Decision-Making Skills of Operating Room Nurses Regarding Knowledge of Inadvertent Perioperative HypothermiaNot yet recruitingNCT07429084
- Predicting Hypothermia in Gynecological Laparoscopic Surgery Using Machine LearningNot yet recruitingNCT073535281 country
- Clinical Evaluation of Effectiveness of the "Therm'Up" Heating DeviceEnrolling by invitationNCT06788925Not applicable1 country
- Neuroprotective Effect of Mild Hypothermia Versus Normothermia During Cardiopulmonary Bypass of Coronary Artery SurgeryNot yet recruitingNCT07316868Not applicable1 country
- Intracoronary Hypothermia as a Prevention of Reperfusion Injury in Myocardial Infarction.RecruitingNCT06567249Not applicable1 country
- Evaluation of MTH in PCI Under VA-ECMO for AMICSNot yet recruitingNCT07186972Not applicable
- The Effect of Warmed Socks Developed as Wearable Technology on Hypothermia, Thermal Comfort Perception and ShiveringNot yet recruitingNCT06283771Not applicable
- The Effect of Heating the Intensive Care Room in the Early Postoperative Period on Patient OutcomesRecruitingNCT07137143Not applicable1 country
- Multicenter Application of the Intraoperative Hypothermia Risk Prediction Scale and the Distribution of Risk Factor Characteristics in Surgical PatientsEnrolling by invitationNCT068362451 country
- Study on Optimal Temperature During Cardiopulmonary Bypass (THERMIC-4)RecruitingNCT05996120Not applicable1 country
- Constructing a Risk Prediction Model for Intraoperative Hypothermia in Children Under General AnesthesiaEnrolling by invitationNCT068927951 country
- Active External Rewarming from Accidental Hypothermia - a Dose-response Pilot StudyEnrolling by invitationNCT06855173Not applicable1 country
- Comparison of the Effect of Prewarming on Intraoperative Hypothermia in Patients Undergoing Holmium Laser ProstatectomyNot yet recruitingNCT06847659Not applicable1 country
- Combination of Hypothermia and Thrombectomy in Acute StrokeRecruitingNCT06301412Phase 31 country
- Blood Warming in Preterm Infants to Decrease HypothermiaRecruitingNCT05170633Not applicable1 country
- Quantification of Brain and Kidney Perfusion Before, During, and After Hypothermia Treatment in Neonates With Perinatal Asphyxia Using Contrast-enhanced UltrasoundRecruitingNCT066112541 country
- Evaluation of The Relationship Between Perioperative Hypothermia and Emergence AgitationRecruitingNCT065431341 country
- Efficacy of Celsi Warmer for the Management of Hypothermic Newborns at the Lagos University Teaching Hospital in Lagos, NigeriaRecruitingNCT06003140Not applicable1 country
- Temperature Management on Postoperative DeliriumNot yet recruitingNCT06406257Not applicable
- Study to Actively Warm Trauma Patients-2Not yet recruitingNCT06322186Not applicable
- A Risk Prediction Model for Hypothermia After Laparoscopic Gastrointestinal Tumor SurgeryNot yet recruitingNCT05958550
- Early Weaning From Incubator To CribRecruitingNCT06230172Not applicable1 country
- International Registry of Accidental HypothermiaRecruitingNCT062002859 countries
- Comparisons of Two Different Type Heater in Different Inhalation Anesthesia in Terms of Prevention of HypothermiaRecruitingNCT06107647Not applicable1 country
- Efficacy of Celsi Warmer for the Management of Hypothermic NewbornsRecruitingNCT06000826Not applicable1 country
- Efficacy of a Low-cost Warming Mattress Celsi Warmer for the Management of Hypothermic Newborns at Muhimbili National Hospital, Dar es Salaam, TanzaniaRecruitingNCT05876884Not applicable1 country