AstraZeneca: Hypertriglyceridemia trials

The registry lists 12 Hypertriglyceridemia studies with AstraZeneca as lead sponsor. 0 are open to participants now and 9 have results posted.

Phase 1 4Phase 2 3Phase 3 5Phase 4 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• AZD0585 Phase III Long-term Study in JapanCompletedNCT02463071Phase 3Results posted
• A Double-blind Randomized Placebo-controlled Study Comparing Epanova and Fenofibrate on Liver Fat in Overweight Subjects.CompletedNCT02354976Phase 2Results posted
• An Open-Label Crossover Study to Compare the Relative Bioavailability, Efficacy and Safety of Epanova® and Lovaza® in Men and Women With a History of PancreatitisCompletedNCT02189252Phase 1Results posted
• Epanova® for Lowering Very High Triglycerides II (EVOLVE II)CompletedNCT02009865Phase 3Results posted
• [E]PANOVA Combined With a [S]TATIN in [P]ATIENTS With HYPERT[R]IGLYCER[I]DEMIA to Reduce Non-HDL CHOLES[T]EROLCompletedNCT01408303Phase 3Results posted
• Epanova® for Lowering Very High TriglyceridesCompletedNCT01242527Phase 2/3Results posted
• Epanova® Compared to Lovaza® In a Pharmacokinetic, Single-dose, EvaluationCompletedNCT01208961Phase 2Results posted
• Safety and Efficacy Study Comparing ABT-143 to Simvastatin in Subjects With Elevated Levels of Low Density Lipoprotein Cholesterol ("Bad Cholesterol") and TriglyceridesCompletedNCT00812955Phase 3Results posted
• Effect of Rosuvastatin on Triglyceride Levels in Mexican Hypertriglyceridemic PatientsCompletedNCT00473655Phase 4Results posted
• Study to Evaluate the 2-Way Interaction Between Multiple Doses of Epanova™ and a Single Dose of Rosuvastatin (Crestor®)CompletedNCT02859129Phase 1
• The Effect of Multiple Doses of Epanova® on the Multiple-Dose Pharmacokinetics of Simvastatin in Healthy Normal SubjectsCompletedNCT01486433Phase 1
• Interaction of Epanova on Warfarin Pharmacokinetic and Anticoagulant Activity and Comparison of the Effects of Epanova and Lovaza on Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) After Low-fat MealsCompletedNCT01431690Phase 1