Hypertriglyceridemia: all 302 studies

Page 1 of 4. Open to participants first (38), then studies with results posted, then the rest; newest registration first within each.

• A Phase 2 Study to Evaluate the Efficacy and Safety of DR10624 in Subjects With Moderate Hypertriglyceridemia and Diabetic Kidney DiseaseNot yet recruitingNCT07848880Phase 2
• Standardized Large Yellow Tea Extract for Glucose and Lipid Metabolism in Overweight Adults With HypertriglyceridemiaNot yet recruitingNCT07840846Not applicable
• Comparing Two Low-Carbohydrate Diets With a Standard Diet in Type 2 DiabetesNot yet recruitingNCT07801378Not applicable
• Icosapent Ethyl for High-Risk Coronary Plaques Assessed by 18F-NaF PET/CTNot yet recruitingNCT07762755Phase 4
• Cardiovascular-Kidney-Metabolic Syndrome RegistryNot yet recruitingNCT07718789
• Plasma Lipids-Dependent Vitamin E Metabolism During Dynamic HyperlipidemiaNot yet recruitingNCT07715890Not applicable
• A Phase III Study to Evaluate the Efficacy and Safety of of DR10624 in Subjects With Severe HypertriglyceridemiaNot yet recruitingNCT07693777Phase 3
• A Phase 3 Trial of DR10624 Versus Placebo in Patients With Severe HypertriglyceridemiaNot yet recruitingNCT07680829Phase 3
• CS-121 APOC3 Base Editing in Severe HypertriglyceridemiaNot yet recruitingNCT07657780Early Phase 1
• GLP-1 Agonists for Prevention of Recurrent Hypertriglyceridemic Acute PancreatitisNot yet recruitingNCT07617155Phase 4
• A Study to Assess the Safety, Tolerability and Efficacy of ION775RecruitingNCT07604974Phase 2
• Pemafibrate for Symptomatic ICAS RCTRecruitingNCT07562178Not applicable
• Russian Extreme Hypertriglyceridemia RegistryRecruitingNCT07508930
• First-in-Human Study of ISH0688: Safety, Tolerability, Pharmacokinetics, and PharmacodynamicsNot yet recruitingNCT07505043Phase 1
• A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory DyslipidemiasRecruitingNCT07491172Phase 1
• A Study of Solbinsiran (LY3561774) in Participants With Severe HypertriglyceridemiaRecruitingNCT07269210Phase 2
• Interest of High-speed Centrifugation for Measuring Anti-Xa Activity on Lipemic PlasmaRecruitingNCT07200674
• A Mechanistic Study of MAR001 in Adults With Elevated Triglycerides and Remnant CholesterolRecruitingNCT07199309Phase 2
• CS-121 APOC3 Base Editing in FCSRecruitingNCT07176923Early Phase 1
• a Phase 1b/2a Study of JMT202 Injection in Participants With HypertriglyceridemiaRecruitingNCT07140809Phase 1/2
• A Trial to Evaluate the Efficacy and Safety of DR10624 in Patients With Hypertriglyceridemia and Carotid Atherosclerotic PlaqueEnrolling by invitationNCT07050134Not applicable
• Study of MAR001 in Adults With Elevated Triglycerides and Remnant CholesterolRecruitingNCT07028749Phase 2
• Effect of Consuming n-3 Polyunsaturated Fatty Acids Rich Foods on Triglyceride Concentration and Lipoprotein CompositionRecruitingNCT07004777Not applicable
• Multicenter Prospective Cohort Study of Hypertriglyceridemia Acute PancreatitisEnrolling by invitationNCT06976099
• Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute PancreatitisRecruitingNCT06880770Phase 3
• Phase 2a Study of Safety, Tolerability, and Efficacy of TLC-2716 in Subjects With Hypertriglyceridemia and NAFLDRecruitingNCT06564584Phase 2
• Exploring Physical Exercise for the Regulation and Control of Metabolic Disorders in College Students.Not yet recruitingNCT06555159Not applicable
• Differential Thrombogenesis by EPA and DHA Mediated by HDLRecruitingNCT06494488Early Phase 1
• Phase 1b Study of VERVE-201 in Patients With Refractory HyperlipidemiaRecruitingNCT06451770Phase 1
• A Study on the Effects of Mastiha Oil in Adults With HypertriglyceridemiaNot yet recruitingNCT06323252Not applicable
• Effects of Phytoestrogen From Pueraria Mirifica in Improvement of Serum Lipid Parameters in Postmenopausal WomenRecruitingNCT06220266Phase 2/3
• Vitamin C Administration and Triglycerides Level in Critical Care PatientsRecruitingNCT06206759
• Study of the Efficacy and Safety of EPA in Patients With Type-2 DiabetesNot yet recruitingNCT06129526Phase 4
• Culturally Adapted Dietary Clinical Trial in PRRecruitingNCT05962372Not applicable
• Safety Study of Fenofibrate During PregnancyRecruitingNCT05883865
• Metabolic Heterogeneity Underlying Hypertriglyceridemia: Hepatic Triglyceride Biosynthesis in Humans With Different Insulin Resistance PhenotypesRecruitingNCT05743868Not applicable
• Impact of Foods on Bile Acids, Metabolites, and InflammationRecruitingNCT05245357Not applicable
• Abnormal Lipids - Causes and EffectsRecruitingNCT02195050
• A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe HypertriglyceridemiaCompletedNCT05355402Phase 2Results posted
• Efficacy and Safety of Evinacumab in Adult Patients With Severe Hypertriglyceridemia for the Prevention of Recurrent Acute PancreatitisTerminatedNCT04863014Phase 2Results posted
• Study to Evaluate ARO-APOC3 in Adults With Severe HypertriglyceridemiaCompletedNCT04720534Phase 2Results posted
• Study to Explore the Efficacy and Safety of BIO89-100 (Pegozafermin) in Participants With Severe HypertriglyceridemiaCompletedNCT04541186Phase 2Results posted
• Assess Efficacy and Safety of Epeleuton in Patients With Hypertriglyceridemia and Type 2 DiabetesTerminatedNCT04365400Phase 2Results posted
• Impacts of Lentils on Metabolism and InflammationCompletedNCT04283448Not applicableResults posted
• Pharmacodynamic Effects of a Free-Fatty Acid Formulation of Omega-3 Pentaenoic Acid in Adults With HypertriglyceridemiaCompletedNCT04177680Phase 2Results posted
• Study of Gemcabene in Adults With FPLDCompletedNCT03508687Phase 1/2Results posted
• Safety and Efficacy Following Repeat-Dose of Evinacumab (Anti-ANGPTL3) in Patients With Severe Hypertriglyceridemia (sHTG) at Risk for Acute PancreatitisCompletedNCT03452228Phase 2Results posted
• A Prospective Observational Program Using Digital Technology Tools to Enhance Patient Adherence to Omacor TherapyCompletedNCT03415152Results posted
• Study of ISIS 678354 (AKCEA-APOCIII-LRx) in Participants With Hypertriglyceridemia and Established Cardiovascular Disease (CVD)CompletedNCT03385239Phase 2Results posted
• Study of ISIS 703802 in Participants With Hypertriglyceridemia, Type 2 Diabetes Mellitus, and Nonalcoholic Fatty Liver DiseaseCompletedNCT03371355Phase 2Results posted
• Effect of Omega-3 Fatty Acids Supplementation on Hypertriglyceridemia in Pediatric Patients With Obesity.CompletedNCT03216057Not applicableResults posted
• Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Mild or Moderate Renal ImpairmentCompletedNCT03011450Phase 3Results posted
• Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Normal Renal FunctionCompletedNCT03001817Phase 3Results posted
• A 12-Week Study to Assess the Efficacy Safety and Tolerability of Gemcabene in Subjects With Severe HypertriglyceridemiaCompletedNCT02944383Phase 2Results posted
• Effect of Vascepa on Improving Coronary Atherosclerosis in People With High Triglycerides Taking Statin TherapyCompletedNCT02926027Phase 4Results posted
• Feasibility and Acceptability of a Beverage Intervention for Hispanic AdultsCompletedNCT02911753Not applicableResults posted
• Orlistat for the Treatment of Type I HyperlipoproteinemiaCompletedNCT02767531Phase 2Results posted
• Open-Label Study To Evaluate MN-001 on HDL & Triglyceride in NASH & NAFLD SubjectsCompletedNCT02681055Phase 2Results posted
• Pentoxifylline Treatment in Acute Pancreatitis (AP)CompletedNCT02487225Phase 3Results posted
• AZD0585 Phase III Long-term Study in JapanCompletedNCT02463071Phase 3Results posted
• A Double-blind Randomized Placebo-controlled Study Comparing Epanova and Fenofibrate on Liver Fat in Overweight Subjects.CompletedNCT02354976Phase 2Results posted
• The COMPASS Study: A Study of Volanesorsen (Formally ISIS-APOCIIIRx) in Patients With HypertriglyceridemiaCompletedNCT02300233Phase 3Results posted
• An Open-Label Crossover Study to Compare the Relative Bioavailability, Efficacy and Safety of Epanova® and Lovaza® in Men and Women With a History of PancreatitisCompletedNCT02189252Phase 1Results posted
• Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With HypertriglyceridemiaCompletedNCT02104817Phase 3Results posted
• Epanova® for Lowering Very High Triglycerides II (EVOLVE II)CompletedNCT02009865Phase 3Results posted
• Change of Fructose to Fat in South AsiansCompletedNCT01562782Not applicableResults posted
• A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on StatinCompletedNCT01492361Phase 3Results posted
• Effects of Acipimox on Mitochondrial Function in ObesityCompletedNCT01488409Phase 2Results posted
• Efficacy of LCQ908 on Cardiovascular RiskTerminatedNCT01474434Phase 2Results posted
• A Study to Evaluate Fenofibrate Combination With Statin in Chinese Patients With DyslipidemicCompletedNCT01462877Phase 4Results posted
• Fructose Consumption and Metabolic DysregulationCompletedNCT01445730Not applicableResults posted
• [E]PANOVA Combined With a [S]TATIN in [P]ATIENTS With HYPERT[R]IGLYCER[I]DEMIA to Reduce Non-HDL CHOLES[T]EROLCompletedNCT01408303Phase 3Results posted
• Long-term Efficacy and Safety Study of TAK-085 in Participants With HypertriglyceridemiaCompletedNCT01350999Phase 3Results posted
• Efficacy of TAK-085 in Participants With HypertriglyceridemiaCompletedNCT01350973Phase 3Results posted
• A Study to Assess the Efficacy and Safety of ETC-1002 in Subjects With Elevated Blood Cholesterol and Either Normal or Elevated TriglyceridesCompletedNCT01262638Phase 2Results posted
• Effect of Statins on Lipid Levels Following the First Acute Coronary Event (MK-0000-204)CompletedNCT01245738Results posted
• Epanova® for Lowering Very High TriglyceridesCompletedNCT01242527Phase 2/3Results posted
• Epanova® Compared to Lovaza® In a Pharmacokinetic, Single-dose, EvaluationCompletedNCT01208961Phase 2Results posted
• Intravenous Fat Emulsions and Premature InfantsTerminatedNCT01096446Not applicableResults posted
• Efficacy and Safety of AMR101 (Ethyl Icosapentate) in Patients With Fasting Triglyceride (Tg) Levels ≥ 500 and ≤ 2000 mg/dLCompletedNCT01047683Phase 3Results posted
• Effect of AMR101 (Ethyl Icosapentate) on Triglyceride (Tg) Levels in Patients on Statins With High Tg Levels (≥ 200 and < 500 mg/dL)CompletedNCT01047501Phase 3Results posted
• The Impact of Omega Three Fatty Acids on Vascular Function in HIVCompletedNCT01041521Phase 4Results posted
• Effects of Prescription Omega-3 Acids on Glucose and Lipoprotein Lipids in Subjects With HypertriglyceridemiaCompletedNCT01034540Not applicableResults posted
• Boosted Lexiva With Lovaza Adjunctive Therapy in Hypertriglyceridemic, HIV-Infected SubjectsCompletedNCT01010399Phase 4Results posted
• Effects of Lovaza on Lipoprotein Composition and Function in Mild HypertriglyceridemiaCompletedNCT00959842Phase 1/2Results posted
• Lovaza® and Microvascular Function in Type 2 DiabetesCompletedNCT00931879Phase 4Results posted
• Fish Oil Study for High Triglyceride Levels in ChildrenCompletedNCT00915902Phase 2/3Results posted
• Open-Label Extension of a Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Lovaza® and Simvastatin Therapy in Hypertriglyceridemic SubjectsCompletedNCT00903409Phase 3Results posted
• A Second Open-Label Extension of a Double-Blind, Parallel, Phase IV Study to Assess the Efficacy and Safety of Adjunctive Lovaza® (Formerly Known as Omacor®) Therapy in Hypertriglyceridemic Subjects Treated With Antara™CompletedNCT00891293Phase 4Results posted
• Changes in Lipids and Safety of Raltegravir in HIV+ Patients With Hyperlipidemia While on Current Standard TherapyCompletedNCT00887653Phase 3Results posted
• Omega-3 Fatty Acids (Lovaza) for Second Generation Antipsychotic-Associated HypertriglyceridemiaCompletedNCT00833976Phase 4Results posted
• Rosiglitazone And Fenofibrate Additive Effects on Lipids (RAFAEL)TerminatedNCT00819910Phase 4Results posted
• Safety and Efficacy Study Comparing ABT-143 to Simvastatin in Subjects With Elevated Levels of Low Density Lipoprotein Cholesterol ("Bad Cholesterol") and TriglyceridesCompletedNCT00812955Phase 3Results posted
• Trial of Lovaza in Adolescents With Mild to Moderately Elevated TriglyceridesTerminatedNCT00672633Phase 2Results posted
• Vascular and Lipid Effects of Omega-3 Fatty Acids in People With Moderately Elevated TriglyceridesCompletedNCT00504309Not applicableResults posted
• Effect of Rosuvastatin on Triglyceride Levels in Mexican Hypertriglyceridemic PatientsCompletedNCT00473655Phase 4Results posted
• Evaluation of Efficacy and Safety of Omacor, Co-Administered With Atorvastatin, in Subjects With HypertriglyceridemiaCompletedNCT00435045Phase 3Results posted
• Omega-3 Fatty Acids for High Triglycerides in HIV-infected PatientsCompletedNCT00346697Phase 4Results posted
• Niacin, N-3 Fatty Acids and Insulin ResistanceCompletedNCT00286234Phase 4Results posted
• Diet, Exercise, Niacin, and Fenofibrate to Reduce Heart Disease Risk Factors in Individuals With HIV Lipodystrophy or DyslipidemiaCompletedNCT00246376Not applicableResults posted

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