HELLP Syndrome clinical trials
The registry lists 35 studies for HELLP Syndrome across more than 10 countries. 10 are recruiting or about to start. 8 of them are mainly about HELLP Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04.
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Who runs them
Maastricht University Medical Center (3) · Assiut University (2) · AYMAN ABDELKADER MOHAMED ABDELKADER (2) · University Hospital Schleswig-Holstein (1) · CHU Mohammed VI Marrakech (1) · University of New Mexico (1) · Africa Clinical Research Network (ACRN) (1) · Preeclampsia Foundation (1)
What is being tested here
Drugs under test in HELLP Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Dec 2026sCD163 in HELLP Syndrome · Assiut University
- Feb 2027PROTECT-Africa: Biomarker Validation for Preeclampsia Triage · Africa Clinical Research Network (ACRN)
Who these studies take
Of the 7 HELLP Syndrome studies recruiting now, 4 (57%) set no upper age limit and 3 (43%) stop at 75 or younger. 2 (29%) take children under 18. 6 (86%) are for women only and 0 (0%) for men only; 2 (29%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 7 (100%) | 1 (14%) |
| 30 | 7 (100%) | 1 (14%) |
| 40 | 7 (100%) | 1 (14%) |
| 50 | 7 (100%) | 1 (14%) |
| 65 | 4 (57%) | 1 (14%) |
| 75 | 4 (57%) | 1 (14%) |
| 85 | 4 (57%) | 1 (14%) |
Across all 35 studies, recruiting or not: 40% stop at 75 or younger and 40% at 65; 31% take children; 97% are for women only and 0% for men only; 34% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 12, 2026.
Started recruiting2
- Preeclampsia Intervention NetherlandsNov 4, 2026NCT06452498
- Community Health Worker Support to Lower Blood Pressure After a Pregnancy With High Blood PressureOct 28, 2026NCT07778966
Studies
Recruiting first, then most recently updated. Showing 35 of 35. search them.
- Preeclampsia Intervention NetherlandsRecruitingNCT06452498Phase 31 country
- Community Health Worker Support to Lower Blood Pressure After a Pregnancy With High Blood PressureRecruitingNCT07778966Not applicable1 country
- PROTECT-Africa: Biomarker Validation for Preeclampsia TriageRecruitingNCT078104391 country
- Vitamin D Supplementation Among Pregnant Women in Uganda for the Prevention of Hypertensive Disorders in Pregnancy, and Other Adverse Maternal and Foetal OutcomesNot yet recruitingNCT07510568Phase 4
- Study of Prognostic Values of Platelet Indices and Inflammatory Markers in Patients With HELLP Syndrome.Not yet recruitingNCT07377786
- sCD163 in HELLP SyndromeNot yet recruitingNCT07209748
- Pilot Project Renal and Cardiovascular Tertiary Prevention in PreeclampsiaRecruitingNCT071513391 country
- PlacEntal Acute Atherosis RefLecting Subclinical AtherosclerosisRecruitingNCT055009891 country
- The Preeclampsia RegistryRecruitingNCT063778781 country
- Liver Disease in PregnancyRecruitingNCT038342851 country
- Analysis of Biological Progression and Regression of HELLP Syndrome in TimeCompletedNCT067589601 country
- Free DNA and Nucleosome Concentrations in Pathological PregnanciesCompletedNCT017368261 country
- Trends in Pregnancy Outcomes Beyond Twenty Weeks Gestational Age in Assisted Reproductive Technology Conceived Pregnancies in British ColumbiaCompletedNCT06726603
- BH4 Blood Levels Variations in Pre Eclamptic WomenCompletedNCT058473611 country
- Complement Regulation to Undo Systemic Harm in PreeclampsiaTerminatedNCT04725812Phase 21 country
- The Use of Eculizumab in HELLP SyndromeCompletedNCT04103489Phase 11 country
- Effect of Acetaminophen on Postpartum Blood Pressure Control in Preeclampsia With Severe FeaturesCompletedNCT02911701Phase 41 country
- Pregnancy-Related Hypertension: Adherence to a New Type of MonitoringCompletedNCT04823949Not applicable1 country
- Influence of Conditional Workout Postpartum on Arterial Stiffness Among Women With Status After Preeclampsia, Superimposed Preeclampsia or HELLP-syndromeCompletedNCT02754778Not applicable1 country
- Evaluation of the Serum Markers sFLt1 and PlGF for the Prediction of the Complications of the Placental Vascular Pathologies in the 3rd Quarter of the Pregnancy.CompletedNCT034553871 country
- Early Vascular Adjustments to Prevent PreeclampsiaCompletedNCT042167061 country
- Effectivity of Postpartum Dexamethasone for Women With Class I HELLP SyndromeTerminatedNCT00711841Phase 41 country
- Pancreatic Stone Protein (PSP) in Pregnant WomenStatus unknownNCT022472971 country
- Correlation of Survival in Puerperae by Electrical Impedance TomographyCompletedNCT03715647
- TTP and aHUS in Complicated PregnanciesStatus unknownNCT036055111 country
- Women Specific Cardiac Recovery After PreeclampsiaStatus unknownNCT028073241 country
- General Anesthesia Versus Spinal Anesthesia in Patients of HELLP SyndromeCompletedNCT03111446Not applicable1 country
- A Randomized Control Trial of Vitamin D Prophylaxis in the Prevention of Hypertensive Disorders of PregnancyStatus unknownNCT02920593Phase 41 country
- Promising Bimarker Prediction of Outcome of HELLP Syndrome.CompletedNCT03246542
- Immature Platelet Fraction as a Promising Biomarker in Prediction Outcome of HELLP SyndromeCompletedNCT03232359
- Calcium for Pre-Eclampsia Prevention (CPEP)CompletedNCT00000534Phase 3
- Labetalol Versus Magnesium Sulfate (MgSO4) for the Prevention of Eclampsia TrialWithdrawnNCT00293735Phase 2/32 countries
- RCT of Antioxidant Therapy to Prevent Preeclampsia in BrazilCompletedNCT00097110Phase 31 country
- Doppler and Biological Second Trimester Placental Insufficiency ScreeningCompletedNCT004656341 country
- Dexamethasone Efficacy in HELLP I SyndromeStatus unknownNCT01138839Phase 31 country