Hyperprolactinemia clinical trials
The registry lists 39 studies for Hyperprolactinemia across more than 10 countries. 4 are recruiting or about to start. 18 of them are mainly about Hyperprolactinemia (how this is decided). Per ClinicalTrials.gov, last updated 2026-04-30.
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Who runs them
Pfizer (2) · Massachusetts General Hospital (2) · Changchun GeneScience Pharmaceutical Co., Ltd. (2) · Shanghai Mental Health Center (2) · University Hospitals Coventry and Warwickshire NHS Trust (1) · Cedars-Sinai Medical Center (1) · Fayoum University (1) · The University of Hong Kong (1)
What is being tested here
Drugs under test in Hyperprolactinemia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Cabergoline | 3 | 2 | 3 |
| Aripiprazole | 0 | 0 | 5 |
| KISS1 protein, human | 0 | 0 | 1 |
| Ropinirole | 0 | 0 | 1 |
| Metformin | 0 | 0 | 1 |
| Calcium | 0 | 1 | 1 |
| Vitamin D | 0 | 1 | 1 |
| Amantadine | 0 | 0 | 1 |
| Bromocriptine | 0 | 1 | 1 |
Drug classes tested here Dopamine agonists 3 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3, phase 3 first
- Nov 2026A Phase III Clinical Study of Cabergoline Tablets Compared With Bromocriptine Mesylate Tablets · Phase 3 · Changchun GeneScience Pharmaceutical Co., Ltd.
- Aug 2027Safety and Potency of a High Cabergoline Dosage in Microprolactinomas · Phase 3 · University of Sao Paulo General Hospital
- Nov 2026Impact of Helicobacter Pylori Infection on Prolactin Levels in Reproductive-Age Women to Determine Whether H. Pylori Infection is Associated with Elevated Prolactin Levels and Assess the Clinical Implications · Assiut University
Who these studies take
Of the 3 Hyperprolactinemia studies recruiting now, 2 (67%) set no upper age limit and 1 (33%) stop at 75 or younger. 0 (0%) take children under 18. 2 (67%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 3 (100%) | 1 (33%) |
| 30 | 3 (100%) | 1 (33%) |
| 40 | 3 (100%) | 1 (33%) |
| 50 | 2 (67%) | 1 (33%) |
| 65 | 2 (67%) | 1 (33%) |
| 75 | 2 (67%) | 1 (33%) |
| 85 | 2 (67%) | 1 (33%) |
Across all 39 studies, recruiting or not: 67% stop at 75 or younger and 59% at 65; 31% take children; 38% are for women only and 5% for men only; 21% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 39 of 39. search them.
- Safety and Potency of a High Cabergoline Dosage in MicroprolactinomasRecruitingNCT07463235Phase 31 country
- A Phase III Clinical Study of Cabergoline Tablets Compared With Bromocriptine Mesylate TabletsRecruitingNCT07124221Phase 31 country
- Metabolic Outcomes in Patients With Prolactinomas Under Dopamine Agonist TreatmentRecruitingNCT07045935Phase 41 country
- Impact of Helicobacter Pylori Infection on Prolactin Levels in Reproductive-Age Women to Determine Whether H. Pylori Infection is Associated with Elevated Prolactin Levels and Assess the Clinical ImplicationsNot yet recruitingNCT06870773
- PROSA: Prolactin, Sex Hormones, Growth and Metabolic Biomarkers in Children and Adolescents on AntipsychoticsCompletedNCT050331191 country
- Prevalence of Hyperprolactinemia in Systemic SclerodermaCompletedNCT047463131 country
- A Study on Bioequivalence of Cabergoline Tablets in Human BodyActive, not recruitingNCT07008417Phase 11 country
- Administration of Kisspeptin in Patients With HyperprolactinemiaCompletedNCT02956447Phase 21 country
- Kisspeptin Administration in the AdultCompletedNCT00914823Phase 11 country
- Treatment of Hyperprolactinemia With the Non-ergoline Dopamine Agonist RopiniroleCompletedNCT03038308Phase 1/21 country
- Clinical Efficacy and Adverse Reactions of Antipsychotic TreatmentCompletedNCT06326840Not applicable1 country
- Hyperprolactinemia and Adrenal SteroidogenesisTerminatedNCT041463891 country
- Antipsychotic Induced Hyperprolactinemaia as Risk Factor for Periodontitis in Schizophrenic PatientsCompletedNCT060409441 country
- Clinical Guidance for Proper Treatment of Unexplained Resistant Hyperprolactinemia.CompletedNCT04262024Phase 11 country
- Prolactin Change in Chinese Patients With Schizophrenia After Antipsychotics TreatmentCompletedNCT040022581 country
- Develop and Implement Methods for Diagnostic and Treatment of Hormonal Disorders in Patients With Chronic Kidney DiseaseStatus unknownNCT044397471 country
- Double-Blind Placebo Controlled Study of Adjunctive Aripiprazole for Symptomatic Hyperprolactinemia In Premenopausal Women With SchizophreniaCompletedNCT01338298Not applicable1 country
- Effects of Hyperprolactinemia Induced by Antipsychotic Drugs on Bone MetabolismStatus unknownNCT036757501 country
- Pituitary Function and Spontaneous Intracranial HypotensionSuspendedNCT026035491 country
- Effectiveness and Safety of Bushen Culuan Decoction for Anovulatory InfertilityStatus unknownNCT03709849Phase 2
- The Luveris In Vitro Fertilization TrialTerminatedNCT00889512Phase 41 country
- Hyperprolactinaemia Management in Reproductive Services at University Hospital of Coventry and WarwickshireCompletedNCT035697871 country
- Calcium and Vitamin D to Optimize Bone Mass in Boys With Risperidone-induced HyperprolactinemiaCompletedNCT00799383Phase 31 country
- Substrate Metabolism and Insulin Sensitivity in Patients With Hyperprolactinemia Before and After TreatmentWithdrawnNCT006995301 country
- Pituitary Histopathology and Hyperprolactinaemia and Risk of Glucose Metabolic Disturbances in Acromegaly.Status unknownNCT020921291 country
- Mathematical Model for the Human Menstrual Cycle, Endocrinological Diseases and Fertility Treatment-PAEONCompletedNCT020986681 country
- Aripiprazole and Prolactin StudyCompletedNCT01085383Phase 41 country
- Peony-Glycyrrhiza Decoction (PGD) for Antipsychotic-induced Hyperprolactinemia in Patients With SchizophreniaCompletedNCT01852331Phase 21 country
- Study On Utilization Of Cabergoline For Compliance With Risk Minimization Activities (SUCRE)CompletedNCT01270711
- Adjunctive Aripiprazole in the Treatment of Risperidone-Induced HyperprolactinemiaStatus unknownNCT02013232Not applicable1 country
- The Relationship of PRL and Polycystic Ovary Syndrome (PCOS) in Taiwan's WomenCompletedNCT011172721 country
- Study of Amantadine for Risperidone Consta or Paliperidone Treated Patients to Decrease Prolactin ElevationTerminatedNCT00975611Phase 41 country
- A Multicenter Study to Evaluate the Effects of Switching to Aripiprazole 12 Weeks on the Sexual Dysfunction From Risperidone or Paliperidone in Patients With Schizophrenia Spectrum Disorders or Bipolar Spectrum DisordersStatus unknownNCT01742390Phase 41 country
- The Association Between Dopamine Agonists and Cardiac Valvulopathy, Fibrosis and Other Cardiopulmonary EventsCompletedNCT01052948
- Endometriosis Patients Undergoing Quinagolide TreatmentCompletedNCT00625950Phase 41 country
- Reversal of Antipsychotic-Induced Hyperprolactinemia, Weight Gain, Hyperglycemia and DyslipidemiaStatus unknownNCT00541554Phase 4
- Insulin Resistance in Women With ProlactinomaCompletedNCT004812991 country
- Characterization of MacroprolactinemiaCompletedNCT004361111 country
- Risperidone-Induced Hyperprolactinemia Treated With BromocriptineStatus unknownNCT00315081Phase 31 country