An observational study in Hyperprolactinemia and Spontaneous Intracranial Hypotension, sponsored by Cedars-Sinai Medical Center. Suspended at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2019-01-31.
Sponsored by Cedars-Sinai Medical Center · Observational
Previous research has identified spontaneous cerebral spinal fluid leakage as a cause for spontaneous intracranial hypotension, leading to positional headache patterns. Typical magnetic resonance imaging findings include subdural fluid collections, enhancement of pachymenginges, engorgement of venous structures, pituitary hyperemia, and sagging of the brain (SEEPS). Because pituitary hyperemia has been documented in cases of spontaneous cerebral spinal fluid leakage and is known to mimic a pituitary tumor or hyperplasia, the investigators would like to like to assess the clinical manifestations and neuroimaging abnormalities of SIH patients with regard to the pituitary gland. Specifically, the investigators are looking to analyze the compression of the pituitary stalk and conduct a systemic evaluation of pituitary function in SIH patients.
39 studies on the registry are indexed under Hyperprolactinemia; 4 are open to participants now.
This study's planned enrollment of 100 is below the median of 114 across 16 observational studies indexed under Hyperprolactinemia.
Browse Hyperprolactinemia studies →Cedars-Sinai Medical Center is the lead sponsor of 456 studies on the registry; 107 are open to participants now.
Of its 65 completed or terminated interventional studies of FDA-regulated products, 49 (75%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients with Spontaneous intracranial hypotension (SIH)
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Exclusion Criteria:
Other: Pituitary panel will be drawn pre-op and post-op for all patients.
Comparing the levels of prolactin pre and post treatment
Time frame: 90 days
This study is suspended, as verified in Jan 2019. You cannot join it, but the record below documents what was studied.
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