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Hyperpigmentation clinical trials

The registry lists 127 studies for Hyperpigmentation across more than 10 countries. 28 are recruiting or about to start. 88 of them are mainly about Hyperpigmentation (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06. Counting its 3 narrower conditions too, such as Melanosis: 315 studies, 72 open.

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Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

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· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

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Status

Completed
80
Recruiting
16
Not yet recruiting
10
Status unknown
10
Terminated
4
Active, not recruiting
3

Phase

Phase 2
11
Phase 4
11
Phase 3
8
Phase 1
5

Where

United States
34
Egypt
12
Brazil
10
Thailand
7
Pakistan
6
China
4

Who runs them

Cosmetique Active International (11) · Cryonove Pharma (9) · Cairo University (5) · Revision Skincare (4) · King Edward Medical University (3) · Henry Ford Health System (3) · Massachusetts General Hospital (2) · NovoBliss Research Pvt Ltd (2)

What is being tested here

Drugs under test in Hyperpigmentation studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Tranexamic Acid115
Azelaic acid003
Tretinoin012
Melatonin001
Adapalene001
Bakuchiol001
Tazarotene001
Trichloroacetic Acid001
Epidermal Growth Factor001
Desonide001

Coming up

1phase 3 study under way
7studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 7, phase 3 first

Who these studies take

Of the 16 Hyperpigmentation studies recruiting now, 8 (50%) set no upper age limit and 8 (50%) stop at 75 or younger. 2 (13%) take children under 18. 5 (31%) are for women only and 0 (0%) for men only; 8 (50%) take healthy volunteers.

Recruiting studies that take each age, of 16
AgeWomenMen
102 (13%)2 (13%)
1813 (81%)10 (63%)
3015 (94%)11 (69%)
4015 (94%)11 (69%)
5013 (81%)9 (56%)
6510 (63%)8 (50%)
758 (50%)7 (44%)
858 (50%)7 (44%)

Across all 127 studies, recruiting or not: 68% stop at 75 or younger and 54% at 65; 9% take children; 22% are for women only and 0% for men only; 55% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Hyperpigmentation studies take

Of 64 interventional studies with no phase under Hyperpigmentation, half reached primary completion within 7 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase7 mo3–25 · 64 studies3 mo3–10 · 27 studies10 mo5–27 · 37 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Results posted1

Newly registered3

Studies

Recruiting first, then most recently updated. Showing 50 of 127. Browse all 127 → or search them.