Hyperoxia clinical trials
The registry lists 123 studies for Hyperoxia across more than 10 countries. 20 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-11.
Status
- Completed
- 75
- Status unknown
- 19
- Recruiting
- 11
- Not yet recruiting
- 7
- Terminated
- 6
- Enrolling by invitation
- 2
Phase
- Phase 4
- 8
- Phase 2
- 6
- Phase 1
- 3
- Phase 3
- 3
- Early Phase 1
- 1
Where
- United States
- 21
- China
- 12
- Turkey
- 11
- France
- 9
- Canada
- 9
- Denmark
- 7
Who runs them
Capital Medical University (8) · Medical University of Vienna (5) · University of Edinburgh (4) · Istanbul University (3) · Laval University (3) · University Hospital Bispebjerg and Frederiksberg (3) · Tepecik Training and Research Hospital (3) · Direction Centrale du Service de Santé des Armées (3)
Studies
Recruiting first, then most recently updated. Showing 50 of 123 — search for more.
- Can Brief Exposure to Hyperoxia Improve Function After Chronic Spinal Cord Injury?RecruitingNCT05467215Early Phase 11 country
- Hyperoxia During Outpatient Pulmonary Rehabilitation in Chronic Lung Disease - Does it Matter?RecruitingNCT06776731Not applicable1 country
- Sleep Apnea in ElderlyRecruitingNCT02703220Phase 41 country
- ORI-Guided Oxygen Therapy During One-Lung VentilationNot yet recruitingNCT07720778Not applicable1 country
- Treating Spinal Cord Injury With Early Normobaric HyperoxiaRecruitingNCT07465302Phase 21 country
- Oxygen Reserve Index-Guided Oxygen Titration During Surgery in the Beach Chair PositionNot yet recruitingNCT07404267Not applicable1 country
- HYPER MIND - Hyperoxia Effects on Cerebral HemodynamicsRecruitingNCT07377162Not applicable1 country
- The Effect of Respiratory Challenge on the BOLD SignalEnrolling by invitationNCT04258774Not applicable1 country
- Association Between Early FiO₂ Exposure and Changes in the Uric Acid/Albumin Ratio in Septic ICU PatientsNot yet recruitingNCT07332637
- Effect of Hydrogen Gas on Hyperbaric Oxygen ToxicityNot yet recruitingNCT07263399Not applicable1 country
- Adjuvant Cerebroprotection Using Normobaric Hyperoxia in Pre-hospital Patients with Suspected StrokeNot yet recruitingNCT06801457Phase 31 country
- Oximeters and Skin Pigment: Impact of Skin Pigmentation on Accuracy of Pulse OximetryRecruitingNCT056902691 country
- Effects of Intermittent Hypoxia-Hyperoxia in Older AdultsNot yet recruitingNCT06686316Not applicable
- Acute Effects of Intermittent Hypoxia-Hyperoxia in Older AdultsNot yet recruitingNCT06686238Not applicable1 country
- Effects of Pre-dive Ketone Food Products on Latency to CNS Oxygen Toxicity (Aim 1)Enrolling by invitationNCT05801120Not applicable1 country
- Lung Ultrasound Guided Choice of Best Positive End-Expiratory Pressure in Neonatal AnesthesiaRecruitingNCT05737407Not applicable1 country
- Oxidative Lipidomic Biomarkers During Mechanical Ventilation in Critically Ill Patients (OXY-BAL).RecruitingNCT054128101 country
- Normobaric Hyperoxia Combined With Intravenous Thrombolysis for Acute Ischemic Stroke：Longterm Outcome (OPENS-3L)RecruitingNCT05965193Phase 31 country
- Hyperoxia Induced Pulmonary Inflammation and Organ Injury: a Human in Vivo ModelRecruitingNCT05414370Not applicable1 country
- Impact of Hyperoxia and Involvement of the Immune System in Diving AccidentRecruitingNCT04791488Not applicable1 country
- Automated Oxygen Delivery by O2matic to Patients Admitted With an Exacerbation in COPDCompletedNCT03464695Not applicable1 country
- Effects of Hypoxic-hyperoxic Preconditioning in Cardio-surgical PatientsCompletedNCT05354648Not applicable
- Cerebral Hemodynamic Effects of Oxygen and Antioxidants (CHEOXANT)CompletedNCT07369232Not applicable1 country
- Oxygen as a Metabolic Modulator: Divergent Physiological Adaptations to Hypoxic and Hyperoxic Tabata Training.CompletedNCT07551869Not applicable1 country
- Strategy to Avoid Excessive Oxygen Using an Autonomous Oxygen Titration InterventionCompletedNCT06374225Not applicable1 country
- Effect of Hyperoxia or Hypoxemia on the Incidence of Delirium in Patients After Cardiac SurgeryCompletedNCT075489051 country
- ORI and ETCO₂ Relationship With Arterial Blood Gas During Apnea TestCompletedNCT069839901 country
- Perioperative Hyperoxia vs Normoxia Biomarker TrialCompletedNCT07525661Not applicable1 country
- Hyperoxia vs Normoxia During Cardiopulmonary BypassCompletedNCT07510672Not applicable1 country
- Comparison of Two FiO2 (1 or 0.5) for Tracheal Extubation in Post-anesthesia Care UnitCompletedNCT04879290Not applicable1 country
- The Association Between Sensory Block Level, Oxygen Therapy, and ORi in Varicose Vein Patients Undergoing Spinal Anesthesia (ORi: Oxygen Reserve Index)CompletedNCT065666901 country
- Oxygen Reserve Index Guided FiO₂ Titration in One-Lung VentilationCompletedNCT07359833Not applicable1 country
- Effect of Hyperbaric Oxygen Therapy on MicrocirculationCompletedNCT03980210Not applicable1 country
- Can Atelectasis Be Prevented With Oxygen Reserve Index (ORI) Monitoring?CompletedNCT07050719Not applicable1 country
- Automated Versus Manual Oxygen Control in Preterm Babies on Respiratory SupportCompletedNCT06622161Not applicable1 country
- Effect of ORI-guided Oxygen Titration on Oxidative Stress in Rhinoplasty SurgeryCompletedNCT07158073Not applicable1 country
- Automated Adjustment of Oxygen on Patient With Acute COPD Exacerbation - FreeO2 HypHopTerminatedNCT03835741Not applicable1 country
- NICU Oxygen Control StudyCompletedNCT04269161Not applicable1 country
- Delayed Cord Clamping With Oxygen In Extremely Low Gestation InfantsActive, not recruitingNCT04413097Not applicable1 country
- Impact of Perioperative Hyperoxia on Cancer Recurrence and Mortality After Elective Colorectal Cancer SurgeryCompletedNCT069893461 country
- Normobaric Hyperoxia for Intracerebral HemorrhageCompletedNCT04144868Phase 21 country
- Electronic Optimization of Inspired Oxygen During Mechanical Ventilation, a Pragmatic Randomized Trial (OPTI-Oxygen)SuspendedNCT05923853Not applicable1 country
- Normobaric Hyperoxia Combined with Endovascular Therapy in Patients with Stroke Within 6 Hours of Onset：longterm OutcomeCompletedNCT05039697Not applicable1 country
- Intermittent Hypoxia-Hyperoxia Training in Cerebral Venous Outflow Disorders (IHHT-CVOD)CompletedNCT06738706Not applicable1 country
- Servo Controlled Oxygen Targeting (SCO2T) Study: Masimo vs. NellcorCompletedNCT04866342Not applicable1 country
- The Effect of Hyperoxia and Hypoxia on Fluorescence Lifetime Imaging Ophthalmoscopy in Healthy Subjects- a Randomized, Double Blind, Crossover StudyCompletedNCT04094285Phase 21 country
- Normobaric Hyperoxia Combined With Endovascular Treatment for Acute Ischemic StrokeCompletedNCT05128422Not applicable1 country
- The Effect of Intraoperative Hyperoxemia on Postoperative Delirium in Geriatric PatientsCompletedNCT063263721 country
- Intermittent Hypoxia-hyperoxia Therapy in Obese Patients (IHHTOP)CompletedNCT06451601Not applicable1 country
- The Role of Hyperoxia in Acute Ischemic StrokeTerminatedNCT03904017Not applicable1 country