An interventional study of FreeO2 and manual titration in Oxygen Toxicity, COPD Exacerbation and Hyperoxia, sponsored by Laval University. Terminated at 1 site in Canada. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-09-04.
Sponsored by Laval University · Not applicable, Interventional, and Treatment
The aim of this study is to evaluate if automated adjustment of oxygen (with FreeO2 device) can reduce the hospital length of stay for acute exacerbation of COPD with comparison of manual oxygen titration.
The aim of this study is to evaluate if automated adjustment of oxygen (with FreeO2 device) can reduce the hospital length of stay for acute exacerbation of COPD with comparison of manual oxygen titration.
Patients with severe acute exacerbation of COPD requiring hospitalization will be included in this randomized controlled study and will be managed with either manual oxygen titration or automated oxygen titration (FreeO2 arm).
The impact on the hospital length of stay will be evaluated.
115 studies on the registry are indexed under Hyperoxia; 13 are open to participants now.
This study's enrollment of 17 is below the median of 48 across 82 interventional studies indexed under Hyperoxia.
Browse Hyperoxia studies →Laval University is the lead sponsor of 380 studies on the registry; 67 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.
COPD
Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
In this arm, an automated adjustment of oxygen during patient hospitalisation by FreeO2 device
Device: FreeO2
In this arm, a manual adjustment of oxygen during patient hospitalisation by hospital staff
Other: manual titration
an automated adjustment of oxygen during patient hospitalisation by FreeO2 device
a manual adjustment of oxygen during patient hospitalisation by hospital staff
Hospital length of stay
Duration of the hospital length of stay
Time frame: From hospital admission until hospital discharge (around one week expected)
ICU transfer
The rate of ICU admission during hospital stay
Time frame: During hospital stay : from hospital admission until hospital discharge (around one week expected)
Oxygen administration duration
The number of days patient receive oxygen supplementation
Time frame: During hospital stay : from hospital admission until hospital discharge (around one week expected)
Non invasive or invasive mechanic ventilation rate use
The rate of NIV use during length of stay in hospital
Time frame: During hospital stay: from hospital admission until hospital discharge (around one week expected)
Arterial or Capillary blood gaz evolution
Evaluation of the rate of respiratory acidosis (pH\<7.35 and PaCO2\>45mmHg)
Time frame: During hospital stay - From hospital admission until hospital discharge (around one week expected)
Hospital Readmission rate after hospital discharge
Rate of hospital readmission after initial hospital discharge
Time frame: Until day 90 after study inclusion
Plan to share: No
No publications or documents are linked to this record.
This study is terminated, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.
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