Hypernatremia clinical trials

The registry lists 49 studies for Hypernatremia across more than 10 countries. 8 are recruiting or about to start. 25 of them are mainly about Hypernatremia (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-27.

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Status

Completed: 26
Status unknown: 9
Withdrawn: 5
Recruiting: 5
Not yet recruiting: 2
Enrolling by invitation: 1

Phase

Phase 4: 5
Phase 2: 4
Phase 3: 2
Early Phase 1: 1
Phase 1: 1

Where

United States: 11
Netherlands: 5
Turkey: 4
France: 3
Canada: 3
Denmark: 3

Who runs them

Medical Centre Leeuwarden (3) · University of Connecticut (2) · Catharina Ziekenhuis Eindhoven (2) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (2) · Zekai Tahir Burak Women's Health Research and Education Hospital (1) · Air Force Military Medical University, China (1) · Hospital Pablo Tobón Uribe (1) · Koç University (1)

What is being tested here

Drugs under test in Hypernatremia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Glucose	1	0	2
Saline Solution	0	1	1
Sodium Chloride	0	1	1
Amiloride	0	1	1
Hydrochlorothiazide	0	0	1
Losartan	0	0	1

Who these studies take

Of the 5 Hypernatremia studies recruiting now, 4 (80%) set no upper age limit and 1 (20%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (40%) take healthy volunteers.

Recruiting studies that take each age, of 5
Age	Women	Men
10	0 (0%)	0 (0%)
18	3 (60%)	3 (60%)
30	5 (100%)	5 (100%)
40	5 (100%)	5 (100%)
50	4 (80%)	4 (80%)
65	4 (80%)	4 (80%)
75	4 (80%)	4 (80%)
85	4 (80%)	4 (80%)

Across all 49 studies, recruiting or not: 41% stop at 75 or younger and 37% at 65; 24% take children; 2% are for women only and 4% for men only; 33% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Hypernatremia studies take

Of 12 interventional studies with no phase under Hypernatremia, half reached primary completion within 10 months of starting, counting those still running.

Start to primary completion	Every sponsor	Industry	Non-industry
Interventional, no phase	10 mo3–15 · 12 studies	—	—

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Started recruiting1

Rapid Rehydration for Severe HypernatremiaOct 27, 2026NCT07783191

Newly registered1

Hypernatremia Fluid Therapy in Childhood DiarrhoeaOct 21, 2026NCT07884747

Studies

Recruiting first, then most recently updated. Showing 49 of 49. search them.