Hypernatremia clinical trials
The registry lists 39 studies for Hypernatremia across more than 10 countries. 7 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-15.
Status
- Completed
- 21
- Status unknown
- 6
- Recruiting
- 4
- Not yet recruiting
- 3
- Withdrawn
- 3
- Terminated
- 2
Phase
- Phase 2
- 4
- Phase 4
- 3
- Phase 3
- 3
- Phase 1
- 1
- Early Phase 1
- 1
Where
- United States
- 9
- Netherlands
- 5
- France
- 3
- Turkey
- 3
- Sweden
- 2
- Canada
- 2
Who runs them
Medical Centre Leeuwarden (3) · Catharina Ziekenhuis Eindhoven (2) · University of Connecticut (2) · Insel Gruppe AG, University Hospital Bern (2) · Columbia University (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · University Hospital, Linkoeping (1) · Oakland University (1)
Studies
Recruiting first, then most recently updated. Showing 39 of 39 — search for more.
- Can Changes in Dialysate Sodium Concentration Improve Blood Pressure and Endothelial Function in Chronic HD Patients?Not yet recruitingNCT07459348Not applicable1 country
- Rapid Rehydration for Severe HypernatremiaNot yet recruitingNCT07783191Phase 21 country
- Cardiac Tissue Sodium Assessment in CKD Patients Using Sodium MRIRecruitingNCT048486361 country
- Early Versus Conventional Cessation of Hydrocortisone in Septic ShockRecruitingNCT05818826Phase 21 country
- Dietary Sodium, Oxidative Stress, and Pulsatile HemodynamicsRecruitingNCT04233957Not applicable1 country
- Plasma Sodium and Sodium Administration in the ICURecruitingNCT060379281 country
- A Short, Animated Storytelling Video to Increase Knowledge About Sodium Intake as a Cardiovascular Risk FactorNot yet recruitingNCT05735457Not applicable
- Effects of a Six-Day Whole-Diet Intervention on Taste Perception and Dietary Behaviour in Young AdultsCompletedNCT07726394Not applicable1 country
- Comparing Natriuretic Effects of ER Torsemide to IR Torsemide in Patients With Heart FailureCompletedNCT06995144Phase 41 country
- Vascular Effects of Acute Sodium (VEAS) StudyCompletedNCT04244604Not applicable1 country
- Efficacy and Safety of Rapid Intermittent Correction Compared With Slow Continuous Correction in Patients With Severe HypernatremiaCompletedNCT04949139Phase 41 country
- Amiloride in Nephrotic SyndromeTerminatedNCT05079789Phase 31 country
- Increasing Vegetable Intake Using Monosodium Glutamate: A Reduced-Effort InterventionCompletedNCT05591612Not applicable1 country
- Comparison of Isotonic Versus Hypotonic Fluids in Neonates for Maintenance Fluid Therapy After SurgeryCompletedNCT06484608Not applicable1 country
- Early Induced Hypernatremia for the Prevention and Management of Brain EdemaWithdrawnNCT02798601Not applicable
- Comparison of the Isotonic and Hypotonic Intravenous Maintenance Fluids In Term Newborns: Neofluid StudyCompletedNCT047813611 country
- The Effect of AMP Human Sodium Bicarbonate Lotion on Dehydrated Heat StressCompletedNCT05092854Not applicable1 country
- Prospective Analysis Into Development of Hypernatremia in Critically Ill PatientsStatus unknownNCT050852231 country
- Hypernatremia in Hydatid Cyst TreatmentStatus unknownNCT050900201 country
- The Effect of AMP Human Sodium Bicarbonate Lotion on HydrationCompletedNCT04598386Not applicable1 country
- Low Sodium Neapolitan Pizza Prepared With Seawater: Nutritional Properties, Sensory Characteristics, Metabolic EffectsCompletedNCT04629742Not applicable1 country
- ED Hypernatremia. Prognostic Factors and Epidemiology.Status unknownNCT042659761 country
- Intravenous Fluids in Hospitalised ChildrenCompletedNCT02926989Phase 41 country
- Safety and Efficacy of Hydrochlorothiazide in the Treatment of Hypernatremia in Critically Ill PatientsStatus unknownNCT03658850Phase 21 country
- Prospective Data Analysis of the Development of Hypernatremia in Intensive Care UnitCompletedNCT037524501 country
- Relieve the Patient's Thirst, Refresh the Mouth First (ICU-MIC)CompletedNCT03610074Not applicable1 country
- Balance Study on ICU-acquired Hypernatremia and Sodium Handling (BIAS)CompletedNCT030937661 country
- Investigation on Differences in Skin Sodium Content Between Normal Subjects and ICU-patientsCompletedNCT029122991 country
- Hypernatremia for the Prevention and Treatment of Cerebral Edema in Traumatic Brain InjuryWithdrawnNCT01605357Phase 1/2
- V2 Receptor Effects on Fluid Regulation and PerformanceCompletedNCT02084797Not applicable1 country
- Frequency and Origin of Dysnatremias in the Emergency DepartmentWithdrawnNCT01326429
- Continuous Venovenous Hemofiltration Versus Conventional Treatment for Acute Severe HypernatremiaStatus unknownNCT02449382Not applicable1 country
- Hydrochloorthiazide and HypernatriaemieCompletedNCT01974739Not applicable1 country
- Hypotonic Versus Isotonic Parenteral (HIP) Fluid TrialCompletedNCT00734214Phase 31 country
- Treatment of Sodium Retention in Liver Cirrhosis With DexamethasoneTerminatedNCT01311167Phase 31 country
- Use of Sterile Water Feeds for Treatment of Hypernatremia in Extremely Low Birth Weight InfantsCompletedNCT01219179Not applicable1 country
- Do Changes in Plasma Osmolality Influence Ventilation?CompletedNCT01008644Early Phase 11 country
- Physiopathology of Sodium Retention in AcromegalyCompletedNCT00531908Not applicable1 country
- Evaluation of the Cerebral Oxygenation With Near Infrared Spectrophotometry (NIRS) at the Hypernatremic Dehydration in NewbornStatus unknownNCT01299428Not applicable1 country