ClinicalTrials.gg
WithdrawnNCT01326429Updated Jul 23, 2015

Frequency and Origin of Dysnatremias in the Emergency Department

An observational study in Hyponatremia and Hypernatremia, sponsored by Insel Gruppe AG, University Hospital Bern. Withdrawn. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2015-07-23.

Sponsored by Insel Gruppe AG, University Hospital Bern · Observational

Why this study was withdrawn
Job change of responsible investigators
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
0
Ages
18 Years and older
Sex
All
01

Study summary

Hypo- and hypernatremia are the most frequent electrolyte disorders found in hospitalized patients. The increasing use of diuretics and other medications influencing the water and sodium homeostasis potentially lead to a rise in the prevalence of the electrolyte disorders. Only little data is available on the frequency and the mechanisms leading to hypo-/hypernatremia.

Thus, the investigators aim to A.) determine the frequency of hypo- and hypernatremia in the emergency department of a large tertiary university hospital and B.) explore the mechanisms leading to the development of dysnatremias by detailed clinical and laboratory examinations.

02

Conditions studied

  • Hyponatremia
  • Hypernatremia

Keywords

  • Sodium
  • Hyponatremia
  • Hypernatremia
  • Emergency department
03

In context

Hyponatremia

164 studies on the registry are indexed under Hyponatremia; 16 are open to participants now.

Browse Hyponatremia studies →

Lead sponsor

Insel Gruppe AG, University Hospital Bern is the lead sponsor of 741 studies on the registry; 180 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All patients admitted to the emergency department of a large tertiary university hospital with a serum sodium below 135 mmol/L (hyponatremia) or exceeding 145 mmol/L.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Serum sodium below 135 mmol/L (i.e. hyponatremia); serum sodium exceeding 145 mmol/L (hypernatremia)

Exclusion criteria

Exclusion Criteria:

  • Patients below age 18 years; patients declining study participation.
05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
0 participants (actual)
Biospecimen retention
Samples with dna

Groups and cohorts

  • Hypernatremia

    Patients admitted to the emergency department with a serum sodium exceeding 145 mmol/L.

  • Hyponatremia

    Patients admitted to the emergency room with a serum sodium below 135 mmol/L.

06

What researchers measure

Primary outcomes

  1. Frequency of hypo- and hypernatremia in the emergency department

    The investigators aim to determine the frequency of hypo- and hypernatremia in the emergency department of a large tertiary university hospital.

    Time frame: approx. 6 months

Secondary outcomes

  1. Origin of hypo- and hypernatremia in the emergency department

    The investigators try to investigate the mechanisms leading to the development of hypo- and hypernatremia in patients admitted to the emergency department.

    Time frame: approx. 6 months

07

Study locations

No study locations are listed for this record.

08

References and documents

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 23, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT01326429
Collaborators
Steering committee of the NCCR
First posted
Mar 30, 2011
Start date
Oct 2011
Primary completion
Mar 2013
Completion
Mar 2013
Last update
Jul 23, 2015

Study contacts

Gregor Lindner, M.D.
principal investigator · Dept. of Nephrology and Hypertension, Inselspital Bern, University of Bern
Felix J Frey, M.D.
study chair · Dept. of Nephrology and Hypertension, Inselspital Bern, University of Bern

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is withdrawn, as verified in Jul 2015. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion