Hyperhidrosis clinical trials
The registry lists 111 studies for Hyperhidrosis across more than 10 countries. 10 are recruiting or about to start. 108 of them are mainly about Hyperhidrosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-09-10.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Botanix Pharmaceuticals (9) · Journey Medical Corporation (6) · Ulthera, Inc (6) · Allergan (5) · Dr. August Wolff GmbH & Co. KG Arzneimittel (4) · University of Utah (3) · University of Sao Paulo (3) · Cynosure, Inc. (3)
What is being tested here
Drugs under test in Hyperhidrosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Oxybutynin | 1 | 2 | 8 |
| Botulinum toxin type A | 0 | 2 | 12 |
| Glycopyrrolate | 0 | 0 | 5 |
| Sofpironium | 0 | 0 | 4 |
| WO3970 | 0 | 1 | 3 |
| GSK573719 | 0 | 0 | 3 |
| rimabotulinumtoxinB | 0 | 0 | 2 |
| Ethanol | 0 | 0 | 1 |
| Terazosin | 0 | 0 | 1 |
| Magnesium | 0 | 0 | 1 |
Drug classes tested here Antimuscarinics 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Oct 202720% Alcohol With Steroid Local Anesthetic Technique Versus Steroid Local Anesthetic Technique Only in Stellate Ganglion Injection in Idiopathic Palmar Hyperhydrosis · Fayoum University Hospital
- Oct 2027"Incidence of Compensatory Hyperhidrosis After T3 Vs T3-4 Sympathectomy" · Assiut University
Who these studies take
Of the 7 Hyperhidrosis studies recruiting now, 4 (57%) set no upper age limit and 3 (43%) stop at 75 or younger. 1 (14%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (29%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 7 (100%) | 7 (100%) |
| 30 | 7 (100%) | 7 (100%) |
| 40 | 7 (100%) | 7 (100%) |
| 50 | 5 (71%) | 5 (71%) |
| 65 | 5 (71%) | 5 (71%) |
| 75 | 5 (71%) | 5 (71%) |
| 85 | 4 (57%) | 4 (57%) |
Across all 111 studies, recruiting or not: 56% stop at 75 or younger and 41% at 65; 28% take children; 1% are for women only and 3% for men only; 25% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hyperhidrosis studies take
Of 14 phase 2 interventional studies under Hyperhidrosis, half reached primary completion within 8 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 8 mo7–11 · 14 studies | — | — |
| Interventional, no phase | 21 mo6–37 · 20 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 111. Browse all 111 → or search them.
- Targeting Nociceptors in Hidradenitis SuppurativaRecruitingNCT054037101 country
- 20% Alcohol With Steroid Local Anesthetic Technique Versus Steroid Local Anesthetic Technique Only in Stellate Ganglion Injection in Idiopathic Palmar HyperhydrosisNot yet recruitingNCT07788326Not applicable
- Botulinum Toxin Type A for Frontal HyperhidrosisRecruitingNCT07561580Not applicable1 country
- "Incidence of Compensatory Hyperhidrosis After T3 Vs T3-4 Sympathectomy"Not yet recruitingNCT07196319
- A Polymer Film Device to Treat Excessive Palmar SweatingRecruitingNCT06881394Not applicable1 country
- Outcome of Bilateral Thoracoscopic Sympathectomy for Patients with Primary Focal HyperhidrosisRecruitingNCT06638827Not applicable1 country
- Topical Oxybutynin for Treatment of Hyperidrosis: Local or Systemic Effect?RecruitingNCT05102396Phase 21 country
- Treatment and Mapping of Impostor PhenomenonRecruitingNCT05805696Not applicable1 country
- Evaluation of Safety and Efficacy of Morpheus8 Applicator for the Treatment of Focal Hyperhidrosis of the Axillae Using Radio FrequencyRecruitingNCT05860972Not applicable2 countries
- Methotrexate Iontophoresis Versus Coal Tar Ointement in the Treatment of Primary Palmer Hyper HidrosisNot yet recruitingNCT05875285Not applicable1 country
- Image Guided Targeted Photoablation for the Treatment of Localized HyperhidrosisTerminatedNCT04178161Not applicable1 country
- Stellate Ganglion Block Versus Oral Medication in Treatment of Palmar HyperhidrosisCompletedNCT06731101Not applicable1 country
- Qbrexza Cloths for Hyperhidrosis of Amputation SitesCompletedNCT04924036Phase 21 country
- Treatment of Hyperhidrosis With OxybutyninCompletedNCT01855256Phase 31 country
- Comparator Study of the Effect of Glycopyrrolate and Glycopyrronium in Subjects With Axillary HyperhidrosisCompletedNCT02129660Phase 22 countries
- Comparison of the Clinical Efficacy and Adverse Reactions of Different Needling Patterns of High-frequency Microneedles in the Treatment of Axillary OdorCompletedNCT07094009Not applicable1 country
- Severe Primary Hand Hyperhidrosis Treatment With Topical Administration of VictorhyTerminatedNCT06645509Phase 21 country
- Miradry Treatment for Focal Axillary HyperhidrosisTerminatedNCT02295891Not applicable1 country
- Assessment of Safety, Tolerability and Efficacy of 1% GPB Cream Versus Qbrexza® (Glycopyrronium) Cloth 2.4% Under Maximum-Use Conditions in Subjects with Primary Axillary HyperhidrosisWithdrawnNCT04159610Phase 2
- Effect of TENS on Patients With Palmar HyperhidrosisTerminatedNCT06532045Not applicable1 country
- Safety and Efficacy Study of Sofpironium Bromide in Subjects With Axillary Hyperhidrosis (BBI-4000-CL-301)CompletedNCT03836287Phase 31 country
- Safety and Efficacy Study of Sofpironium Bromide in Subjects With Axillary Hyperhidrosis (BBI-4000-CL-302)CompletedNCT03948646Phase 31 country
- Assessment of Safety, Tolerability, Systemic Exposure and Efficacy of GPB Cream in Adolescents With Severe Primary HyperhidrosisCompletedNCT05863104Phase 21 country
- A Non-Interventional Study To Assess SweatingCompletedNCT025521991 country
- Extended Versus Limited Thoracoscopic Sympathectomy: Its Impact on Palmar and Plantar HyperhidrosisCompletedNCT06219655Not applicable1 country
- Patient Satisfaction and Safety of Miradry Treatment for Axillary HyperhidrosisCompletedNCT04546438Not applicable1 country
- Implementation of a Minor Ailment Service in Community Pharmacy PracticeCompletedNCT05247333Not applicable1 country
- Thoracoscopic Sympathetic Chain Interruption for Palmar Hyperhidrosis in Patients Below 18CompletedNCT06113978Not applicable1 country
- miraDry Post Market Tumescent Anesthesia StudyWithdrawnNCT05546710Not applicable
- Evaluation of N-SWEAT Patch for Treatment of Primary Axillary Hyperhidrosis or Excessive Axillary SweatingCompletedNCT04599907Not applicable1 country
- Longevity of Microwave Thermolysis and Botulinum Toxin A for Treatment of Axillary HyperhidrosisCompletedNCT05057117Phase 41 country
- A Safety Study of BBI-4000 Gel in Patients With Axillary HyperhidrosisCompletedNCT03627468Phase 31 country
- A Safety, Tolerability and Preliminary Efficacy Study of BBI-4000 Gel in Subjects With Palmar HyperhidrosisCompletedNCT02682238Phase 21 country
- A Confirmatory Safety and Efficacy Study of BBI-4000 in Subjects With Axillary HyperhidrosisCompletedNCT03024255Phase 2
- Assessment of Efficacy and Safety of Topical Administration of 1% Glycopyrronium Bromide (GPB) in Patients With Primary Axillary Hyperhidrosis and the Assessment of Long-term Efficacy and Safety of Topical Administration of 1% GPB Cream in Patients With Primary Axillary Hyperhidrosis.CompletedNCT03658616Phase 31 country
- Antiperspirant in the Treatment of Residual Limp Hyperhidrosis for Prosthetic UsersCompletedNCT05501444Not applicable1 country
- A Safety and Efficacy Study of BBI-4000 in Subjects With Axillary HyperhidrosisCompletedNCT02336503Phase 21 country
- A Safety Study of BBI-4000 Gel in Pediatric Patients With Axillary HyperhidrosisCompletedNCT03785587Phase 21 country
- A Safety, Tolerability and Preliminary Efficacy Study of BBI-4000 in Subjects With Axillary HyperhidrosisCompletedNCT02058264Phase 1
- Hyperhidrosis in Patients With Amputations-BotoxCompletedNCT03236012Phase 11 country
- Hyperhidrosis, Developing a Treatment Approach Aims 1 & 2CompletedNCT03416348Phase 11 country
- Determination of Longus Colli Muscle Thickness by UltrasonographyCompletedNCT051081031 country
- Botox and Suction-Curettage for Treatment of Excessive Underarm Sweating (Axillary Hyperhidrosis)CompletedNCT01274611Not applicable1 country
- Compensatory Sweating After Unilateral Sympathectomy on the Dominant Side or Bilateral Sequential SympathectomyStatus unknownNCT03921320Not applicable1 country
- Laser Acupuncture Versus Tap Water Iontophoresis on HyperhidrosisCompletedNCT04862546Not applicable1 country
- Long-term Safety Study of Glycopyrronium in Subjects With Primary Axillary HyperhidrosisCompletedNCT02553798Phase 32 countries
- A Dose-Ranging Study of the Effect of Glycopyrrolate in Subjects With Axillary HyperhidrosisCompletedNCT02016885Phase 21 country
- A Study of Glycopyrronium Cloth, 2.4% in Patients With Palmar HyperhidrosisCompletedNCT03880266Phase 21 country
- Study of Glycopyrronium in Axillary HyperhydrosisCompletedNCT02530281Phase 32 countries
- Study of Glycopyrronium in Subjects With Axillary HyperhidrosisCompletedNCT02530294Phase 31 country