An interventional study of Bilateral sequential sympathectomy and Unilateral sympathectomy in Hyperhidrosis Primary Focal Palms, sponsored by University of Sao Paulo. Status unknown at 10 sites in Brazil. Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-10-12.
Sponsored by University of Sao Paulo · Not applicable, Interventional, and Treatment
The standard treatment for palmar hyperhidrosis is bilateral sequential thoracic sympathectomy. High rates of compensatory sweating due to the surgical procedure are described in the literature. In the search for a reduction in this side effect, it is possible that unilateral sympathectomy in the dominant side obtains acceptable results and leads to less compensatory sweating with improvement of the quality of life. The aim of this study it to compare the intensity of compensatory sweating due to the standard treatment, that is, bilateral sequential videothoracoscopic sympathectomy in relation to unilateral thoracic sympathectomy on the dominant side.
111 studies on the registry are indexed under Hyperhidrosis; 10 are open to participants now.
This study's planned enrollment of 200 is above the median of 50 across 99 interventional studies indexed under Hyperhidrosis.
Browse Hyperhidrosis studies →University of Sao Paulo is the lead sponsor of 1,035 studies on the registry; 95 are open to participants now.
Of its 8 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Bilateral sequential (one surgical procedure) videothoracoscopic R4 sympathectomy
Procedure: Bilateral sequential sympathectomy
Unilateral videothoracoscopic R4 sympathectomy on the right (dominant) side
Procedure: Unilateral sympathectomy
Unilateral videothoracoscopic R4 sympathectomy on the left (contralateral) side
Procedure: Contralateral sympathectomy
Bilateral videothoracoscopic sequential R4 sympathectomy
Unilateral videothoracoscopic R4 sympathectomy in dominant side (right side)
Contralateral (left side) videothoracoscopic R4 sympathectomy
Change of sweating intensity
To utilize the HDSS questionnaire to assessment of sweating intensity change in patients with palmar hyperhidrosis treated by bilateral sequential thoracic sympathectomy
Time frame: Change from baseline sweating to 6 months after surgery
Change of sweating intensity
To utilize the HDSS questionnaire to assessment of sweating intensity change in patients with palmar hyperhidrosis submitted to unilateral sympathectomy on the dominant (right) side
Time frame: Change from baseline sweating to 6 months after sympathectomy
Change of sweating intensity
To utilize the HDSS questionnaire to assessment of sweating intensity change in patients submitted to contralateral (left side) sympathectomy after unilateral sympathectomy on the dominant side
Time frame: Change from baseline sweating to 6 months after surgery
Change of Quality of life
To utilize the HidroQOL questionnaire to evaluate the change in quality of life
Time frame: Change from baseline quality of life to 6 months after surgery
Started Mar 2019 (actual). Primary completion is estimated for Jun 2023, 51 months after the start.
Of 20 interventional studies with no phase under Hyperhidrosis, half reached primary completion within 21 months of starting (the median), counting those still running; a quarter within 6 and three quarters within 37. This study's planned 51 months is above that.
How these figures are worked out, and which studies are left out of them.
This study is status unknown, as verified in Oct 2021. You cannot join it, but the record below documents what was studied.
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