Merz Pharma clinical trials

Part of Merz Holding GmbH & Co. KG.

The registry lists 172 studies whose lead sponsor is Merz Pharma or one of 6 companies grouped under it. 3 are recruiting or about to start. Per ClinicalTrials.gov, last updated Oct 20, 2026.

Studies

Recruiting first, then most recently updated. Showing 50 of 172. Browse all 172 →

• A Study to Confirm Safety and Effectiveness of RADIESSE® Injectable Implant for the Correction of Moderate to Severe Nasolabial FoldsNot yet recruitingNCT07856797Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• Real-world Patient Experiences With Inbrija®RecruitingNCT07797790

  Sponsor listed in the registry: Merz Therapeutics GmbH

• Effectiveness and Safety of the Ulthera® System for Skin Laxity in the Lower Face, Submentum and NeckRecruitingNCT07614997Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain InjuryActive, not recruitingNCT03992404Phase 3

  Sponsor listed in the registry: Merz Pharmaceuticals GmbH

• A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Episodic MigraineActive, not recruitingNCT07018700Phase 3

  Sponsor listed in the registry: Merz Therapeutics GmbH

• A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic MigraineActive, not recruitingNCT07018713Phase 3

  Sponsor listed in the registry: Merz Therapeutics GmbH

• Prospective Study to Assess Tissue Responses After Injection With Biostimulatory ProductsCompletedNCT06093815Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• A Study of NT 201 in Adults With Moderate to Severe Platysma Prominence in Europe (PLATINUM EU)Active, not recruitingNCT07210463Phase 3

  Sponsor listed in the registry: Merz Aesthetics GmbH

• A Study of NT 201 in Adults With Moderate to Severe Platysma Prominence in the United StatesActive, not recruitingNCT07122193Phase 3

  Sponsor listed in the registry: Merz North America, Inc.

• A Study of Belotero® Intense Lidocaine for Lip AugmentationCompletedNCT05773066Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• A Study to Investigate the Efficacy and Safety of NT 201 (Botulinum Toxin) Compared With Placebo for the Treatment of Adult Participants With Essential Tremor in the ArmCompletedNCT04766723Phase 2

  Sponsor listed in the registry: Merz Pharmaceuticals GmbH

• Validity and Inter-rater Reliability for Early Recognition of Spasticity Using the Decision Tree ToolCompletedNCT06381999

  Sponsor listed in the registry: Merz Therapeutics GmbH

• A Study to Determine if RADIESSE® Dilute Treatment in Décolleté of Adult Women Affects Radiographic Imaging AssessmentsActive, not recruitingNCT07086248Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• A Clinical Trial to Investigate Efficacy and Safety of NT 201 Injections Compared With Placebo Injections in Participants Aged 18 Years and Older With Chronic Nerve Pain After Shingles or Nerve InjuryCompletedNCT06091020Phase 2

  Sponsor listed in the registry: Merz Therapeutics GmbH

• Evaluation of the Effectiveness and Safety of Diluted RADIESSE® in the Treatment of Décolleté WrinklesCompletedNCT05163353Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• Effectiveness and Safety of the Octave System for Lifting the Eyebrow and Improving the Appearance of the Face and NeckCompletedNCT05067504Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• A Study of NT 201 Doses in the Treatment of Platysma ProminenceCompletedNCT05773053Phase 2

  Sponsor listed in the registry: Merz Aesthetics GmbH

• A Study of NT 201 in the Treatment of Enlarged Pores and Excessive Sebum Production in the FaceCompletedNCT05784363Phase 1

  Sponsor listed in the registry: Merz North America, Inc.

• Assessment of Long-term Clinical Response to BoNT in Cervical DystoniaCompletedNCT05884528

  Sponsor listed in the registry: Merz Therapeutics GmbH

• Safety and Efficacy Study of the Simultaneous Treatment of Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines and Crows Feet) in Subjects With Moderate to Severe Upper Facial LinesCompletedNCT04622254Phase 3

  Sponsor listed in the registry: Merz North America, Inc.

• Safety and Efficacy Study of the Simultaneous Treatment of Upper Facial Lines (Horizontal Forehead Lines, Glabellar Frown Lines and Lateral Canthal Lines) in Subjects With Moderate to Severe Upper Facial LinesCompletedNCT04594213Phase 3

  Sponsor listed in the registry: Merz North America, Inc.

• Evaluation of Effectiveness and Safety of Belotero Balance® (+) Lidocaine for Volume Augmentation of the Infraorbital HollowCompletedNCT04594239Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• A Study of Octave System for Improving Lines and Wrinkles of the DécolletéCompletedNCT04681352Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• Investigation of the Effectiveness and Safety of MRZF111 in the Treatment of Décolleté WrinklesCompletedNCT04177212Not applicable

  Sponsor listed in the registry: Merz Aesthetics GmbH

• Safety, Effectiveness and Participant Satisfaction Study of a Dermal Filler (of RADIESSE® (+) Lidocaine) in the Treatment of Ageing Signs in the FaceCompletedNCT03650387Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• Radiological Evaluation of Radiesse Implantation in the HandsCompletedNCT02949921Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• Study to Investigate the Safety and Duration of Effect of Different Botulinum Toxin A (NT 201) Dose Groups Following the Treatment of Glabellar Frown LinesCompletedNCT03806933Phase 2

  Sponsor listed in the registry: Merz Aesthetics GmbH

• A Pilot Study to Assess the Effectiveness and Safety of Belotero Balance® Injection for Volume Augmentation of the Infraorbital HollowCompletedNCT03777917Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• Evaluation of Effectiveness and Safety of Radiesse (+) to Improve the Contour of Jawline by Adding Volume to the JawlineCompletedNCT03583359Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• Efficacy and Tolerability of Pantovigar® Vegan in Female Subjects With Diffuse Hair LossCompletedNCT05943860Not applicable

  Sponsor listed in the registry: Merz Therapeutics GmbH

• A Study to Evaluate the Distribution of Botulinum Neurotoxin Type A Administered as Intradermal Injections, Comparing Different Doses, Concentrations, and Delivery MethodsCompletedNCT05585398Phase 1

  Sponsor listed in the registry: Merz Pharmaceuticals GmbH

• Longitudinal Evaluation and Real-world Evidence of NT201TerminatedNCT05222607

  Sponsor listed in the registry: Merz North America, Inc.

• A Prospective, Multicenter, Randomized, Comparator-controlled, Evaluator-blinded Study to Evaluate the Safety and Effectiveness of VP1 Lido US for Volume Augmentation of the CheekCompletedNCT04886232Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• Evaluation of the Effectiveness and Safety of the Ulthera® DeepSEE® System for Treating Skin Laxity in the Lower Face and SubmentumCompletedNCT04795622Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• Evaluation of the Effectiveness and Safety of Radiesse for the Correction of Moderate to Severe Nasolabial FoldsCompletedNCT04647721Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• Blepharospasm Patient Survey for Patients With BlepharospasmCompletedNCT01686061

  Sponsor listed in the registry: Merz Pharmaceuticals GmbH

• Open-Label Non-Inferiority Study Evaluating the Efficacy and Safety of Xeomin® in Subjects With Cervical Dystonia FlexCompletedNCT01486264Phase 4

  Sponsor listed in the registry: Merz Pharmaceuticals GmbH

• Local Study of Akatinol Memantine in VaD in RussiaCompletedNCT03986424Phase 3

  Sponsor listed in the registry: Merz Pharmaceuticals GmbH

• Clinical Study to Investigate the Efficacy and Safety of NT 201 Compared to Placebo in the Treatment of Chronic Troublesome Drooling Associated With Neurological Disorders and/or Intellectual DisabilityCompletedNCT02270736Phase 3

  Sponsor listed in the registry: Merz Pharmaceuticals GmbH

• Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Arm(s) or of Arm(s) and Leg(s) in Cerebral PalsyCompletedNCT02002884Phase 3

  Sponsor listed in the registry: Merz Pharmaceuticals GmbH

• Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Leg(s) in Cerebral PalsyCompletedNCT01893411Phase 3

  Sponsor listed in the registry: Merz Pharmaceuticals GmbH

• Safety and Efficacy of NT 201 (IncobotulinumtoxinA [Xeomin]) in the Treatment of Glabellar Frown LinesCompletedNCT00512135Phase 3

  Sponsor listed in the registry: Merz Pharmaceuticals GmbH

• Evaluation of the Effectiveness and Safety of Radiesse for the Correction of Nasolabial Folds in ChinaCompletedNCT03282357Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• Botulinum Toxin A to Treat Arm TremorCompletedNCT02207946Phase 2

  Sponsor listed in the registry: Merz Pharmaceuticals GmbH

• Evaluation of the MJGS Following Radiesse (+) Injection Into the JawlineCompletedNCT02904057Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• Simulines Non-Inferiority Pivotal StudyTerminatedNCT02736825Not applicable

  Sponsor listed in the registry: Ulthera, Inc · First submitted after Ulthera, Inc became part of Merz Pharma

• Radiesse® Safety Study For the Treatment of HandsCompletedNCT02904096Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• Post-Market Clinical Follow-up Performance and Safety Study of Etermis 3 and 4 in the FaceCompletedNCT04210258

  Sponsor listed in the registry: Merz Pharmaceuticals GmbH

• Study of the Cabochon System for Improvement in the Appearance of CelluliteCompletedNCT01671839Not applicable

  Sponsor listed in the registry: Merz North America, Inc.

• Evaluation of Pain With Belotero® Balance With Integral Lidocaine for Correction of the Nasolabial FoldsCompletedNCT03319719Not applicable

  Sponsor listed in the registry: Merz North America, Inc.