Herpes Zoster clinical trials
The registry lists 299 studies for Herpes Zoster across more than 10 countries. 55 are recruiting or about to start. 223 of them are mainly about Herpes Zoster (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
Get an email when these change. Save the Herpes Zoster studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Status
Who runs them
GlaxoSmithKline (43) · Merck Sharp & Dohme LLC (27) · Beijing Tiantan Hospital (12) · NeurogesX (9) · National Institute of Allergy and Infectious Diseases (NIAID) (6) · Tanta University (5) · MAXVAX Biotechnology Limited Liability Company (5) · Shanghai Institute Of Biological Products (4)
What is being tested here
Drugs under test in Herpes Zoster studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Apr 2027Subcutaneous Calcitonin in Acute Herpes Zoster · Phase 3 · Tanta University
- Aug 2027A Study on the Long-term Efficacy, Safety and Persistence of Immune Response of a Vaccine Against Herpes Zoster in Older Adults · Phase 3 · GlaxoSmithKline
- Nov 2026Clinical Trial of Recombinant Herpes Zoster Vaccine (CHO Cell) in Healthy Chinese Population Aged 40 Years and Older · Ab&B Bio-tech Co., Ltd.JS
- Dec 2026Efficacy and Safety of Brivudine in the Treatment of Herpes Zoster · Peking University Third Hospital
- Jan 2027Safety and Immunogenicity of CVI-VZV-001 in Adults Aged 50 Years and Above · Aribio Lab Co., Ltd.
- Feb 2027Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population · National Institute of Allergy and Infectious Diseases (NIAID)
- Mar 2027Immunogenicity and Safety of SYS6017 in the Participants Aged 40 Years and Above · CSPC Megalith Biopharmaceutical Co.,Ltd.
- Mar 2027Recombinant Zoster Vaccine in Young Adult Solid Organ Transplant Recipients · Ann & Robert H Lurie Children's Hospital of Chicago
- May 2027Prospective Biological Study to Evaluate the Persistence of COVID-19 Vaccine and Other Vaccines'-Induced Immune Responses in Follicular Lymphoma Patients Undergoing Frontline Induction Immuno-chemotherapy and Anti-CD20 Maintenance · Fondazione Italiana Linfomi - ETS
- Jun 2027Safety and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix® in Healthy Adults 50 Years of Age and Over · Dynavax Technologies Corporation
Who these studies take
Of the 37 Herpes Zoster studies recruiting now, 26 (70%) set no upper age limit and 6 (16%) stop at 75 or younger. 3 (8%) take children under 18. 2 (5%) are for women only and 0 (0%) for men only; 13 (35%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (8%) | 2 (5%) |
| 18 | 21 (57%) | 20 (54%) |
| 30 | 24 (65%) | 23 (62%) |
| 40 | 31 (84%) | 31 (84%) |
| 50 | 34 (92%) | 33 (89%) |
| 65 | 32 (86%) | 31 (84%) |
| 75 | 30 (81%) | 30 (81%) |
| 85 | 29 (78%) | 29 (78%) |
Across all 299 studies, recruiting or not: 18% stop at 75 or younger and 9% at 65; 5% take children; 1% are for women only and <1% for men only; 44% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Herpes Zoster studies take
Of 40 phase 3 interventional studies under Herpes Zoster, half reached primary completion within 16 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 12 mo9–22 · 21 studies | — | — |
| Phase 2 | 19 mo12–27 · 22 studies | — | — |
| Phase 3 | 16 mo10–45 · 40 studies | 16 mo9–45 · 33 studies | — |
| Phase 4 | 30 mo14–45 · 19 studies | — | — |
| Interventional, no phase | 13 mo9–24 · 34 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Results posted1
- Transcutaneous Auricular Vagus Nerve Stimulation on Post-Herpetic NeuralgiaOct 29, 2026NCT07123987
Newly registered2
- Clinical Trial of Recombinant Herpes Zoster Vaccine (ZFA01 Adjuvant, CHO Cells)Nov 5, 2026NCT07920172
- Immunogenicity and Safety of SYS6052 in the Participants Aged 40 Years and AboveOct 23, 2026NCT07892989
Studies
Recruiting first, then most recently updated. Showing 50 of 299. Browse all 299 → or search them.
- Clinical Trial of Recombinant Herpes Zoster Vaccine (ZFA01 Adjuvant, CHO Cells)RecruitingNCT07920172Phase 1/21 country
- Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control PopulationRecruitingNCT05580458Phase 1/21 country
- Immunogenicity and Safety of SYS6052 in the Participants Aged 40 Years and AboveNot yet recruitingNCT07892989Phase 1/2
- A Study Exploring the Effect of Adjuvanted RZV or RSVPreF3 Vaccines on Coronary Plaque Progression in Adults >=50 Years of Age at Risk for Cardiovascular EventsNot yet recruitingNCT07712380Phase 2
- Comparative Study of Two Vaccination Schedules for the Subunit Herpes Zoster Vaccine in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disease Patients Treated With Anti-CD20 Therapy: an Open-label Randomised Controlled TrialNot yet recruitingNCT07818356Phase 41 country
- The Analgesic Efficacy and Safety of Venlafaxine for Prevention of Postherpetic Neuralgia in Patients With Acute Herpes ZosterRecruitingNCT07361796Not applicable1 country
- Efficacy and Safety of Intravenous Dexamethasone Palmitate Treatments in Acute and Subacute Herpes Zoster PainNot yet recruitingNCT07344246Not applicable1 country
- A Study on the Live-Attenuated Herpes Zoster Vaccine for Sequential Booster Immunization Following Recombinant Herpes Zoster VaccineNot yet recruitingNCT07753265Early Phase 1
- Subcutaneous Calcitonin in Acute Herpes ZosterRecruitingNCT07655804Phase 31 country
- Efficacy of Electroacupuncture for Acute Herpes Zoster-Associated Pain and Biomarker EvaluationRecruitingNCT07515885Not applicable1 country
- Reduced Vaccine Response to HZ/su in SLERecruitingNCT076360441 country
- Long-term Effectiveness of the Live Attenuated Herpes Zoster VaccineRecruitingNCT075853701 country
- A Study to Evaluate the Effect of Recombinant Zoster Vaccine on New Diagnosis of Dementia in an Older Adult Population Aged 76 Years or Older in FinlandRecruitingNCT07502560Phase 41 country
- Shingrix in Renal Transplant RecipientsRecruitingNCT04128189Phase 31 country
- Recombinant Zoster Vaccine in Young Adult Solid Organ Transplant RecipientsEnrolling by invitationNCT06162494Phase 41 country
- The Analgesic Efficacy and Safety of Mirogabalin in Patients With Herpes ZosterRecruitingNCT07307170Not applicable1 country
- A Study to Test GlaxoSmithKline's (GSK) Candidate Vaccine-GSK1437173A for Prevention of Shingles in Children With Kidney TransplantRecruitingNCT04006808Phase 1/26 countries
- Erector Spinae Plane Block Versus Transcutaneous Radiofrequency in Postherpetic NeuralgiaRecruitingNCT074006401 country
- Study to Evaluate the Safety and Immunogenicity of a Lyophilized Herpes Zoster Virus mRNA VaccineRecruitingNCT07400003Phase 1/21 country
- Electroacupuncture Regulation of Immune Cells in Herpes ZosterRecruitingNCT06643247Not applicable1 country
- The Analgesic Efficacy and Safety of Loxoprofen Sodium Patch in Patients With Herpes ZosterRecruitingNCT07378059Not applicable1 country
- The Analgesic Efficacy and Safety of Baclofen in Patients With Herpes ZosterRecruitingNCT07378046Not applicable1 country
- The Analgesic Efficacy and Safety of Flurbiprofen Patch in Patients With Herpes ZosterRecruitingNCT07370402Not applicable1 country
- The Analgesic Efficacy and Safety of Tulodesvenlafaxine in Patients With Herpes ZosterRecruitingNCT07370389Not applicable1 country
- The Analgesic Efficacy and Safety of Desvenlafaxine in Patients With Herpes ZosterRecruitingNCT07361809Not applicable1 country
- Immunogenicity and Safety of SYS6017 in the Participants Aged 40 Years and AboveNot yet recruitingNCT07354659Phase 2
- The Analgesic Efficacy and Safety of Crisugabalin in Patients With Herpes ZosterRecruitingNCT07307976Not applicable1 country
- A Study to Evaluate the Safety of Recombinant Herpes Zoster Vaccine for Healthy IndividualsRecruitingNCT06932523Phase 1/21 country
- Efficacy and Safety of Brivudine in the Treatment of Herpes ZosterRecruitingNCT07099157Phase 41 country
- A Study That Collects Participant Data and Biospecimens to Analyze Pathogenic Exosomes That Mediate Increased Vascular Dementia Risk in Individuals With Herpes Zoster.RecruitingNCT069030781 country
- A Phase 2 Study to Describe the Safety, Reactogenicity, and Immunogenicity of Herpes Zoster IN001 mRNA Vaccine (IN001) in Healthy ParticipantsNot yet recruitingNCT07205796Phase 2
- Clinical Study on the Treatment of Herpes Zoster Pain With Dexmedetomidine Combined With Long-term High VoltageRecruitingNCT06978192Phase 21 country
- Comparative Efficacy of Pregabalin and Lacosamide in Patients With Herpes Zoster and Post Herpetic NeuralgiaRecruitingNCT06969417Not applicable1 country
- Safety and Immunogenicity of SYS6017 in Healthy Participants Aged 40 Years or MoreNot yet recruitingNCT06954818Phase 1
- A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase IV Clinical Trial to Evaluate the Immunogenicity and Safety of a Live Attenuated Herpes Zoster Vaccine in Adults Aged 40 Years and OlderNot yet recruitingNCT06961721Phase 4
- The Efficacy of High-frequency Short-time Spinal Cord Stimulation in the Treatment of Herpes Zoster-associated NeuralgiaRecruitingNCT069428061 country
- Esketamine Combined Pulsed Radiofrequency for Acute/Subacute Zoster-associated Trigeminal NeuralgiaRecruitingNCT06890897Not applicable1 country
- Esketamine Combined With PRF of DRG for Acute/Subacute Zoster-associated PainNot yet recruitingNCT06914206Not applicable1 country
- Safety and Immunogenicity of the Recombinant Zoster Vaccine, LYB004 in Adults Aged 40 Years and OlderRecruitingNCT06874842Phase 11 country
- Neuropathic Pain and Traditional Medicine Syndromes in Herpes Zoster: a Cross-Sectional StudyNot yet recruitingNCT068708771 country
- To Investigate the Relationship Between the Viscoelastic Properties of the Zona Pellucida of Human Oocyte and the Blastocyst Utilization RateRecruitingNCT068394951 country
- A Study to Evaluate the Safety, Tolerability, and Immunogenicity of a Recombinant Herpes Zoster VaccineNot yet recruitingNCT06801509Phase 1/21 country
- Multimodal Nerve Block and Pulse Radiofrequency for Acute Herpes Zoster PainNot yet recruitingNCT06798662Not applicable1 country
- Vaccination Against Herpes Zoster in Patients With Inflammatory Rheumatic DiseasesEnrolling by invitationNCT06763783Phase 41 country
- Impact on Quality of Life and Burden of Disease in Adults With Herpes ZosterNot yet recruitingNCT066672451 country
- Effect of MTX Discontinuation on Shingrix Response in RARecruitingNCT06574594Not applicable1 country
- Risk Factors of Anxiety and Depression in Patients With Herpes Zoster NeuralgiaRecruitingNCT064495471 country
- Ultrasound Guided Serratus Anterior Versus Erector Spinae Block in Pain Alleviation in Acute Herpes ZosterNot yet recruitingNCT06476080Not applicable
- Predictive Models for the Treatment of Recurrent Herpes Zoster Neuralgia Following Spinal Cord Electrical Stimulation.Enrolling by invitationNCT064102221 country
- Immunogenicity of the Recombinant Zoster Vaccine in Multiple Sclerosis PatientsRecruitingNCT05596526Phase 41 country