Merck & Co., Inc: Herpes Zoster trials

The registry lists 27 Herpes Zoster studies with Merck & Co., Inc as lead sponsor. 0 are open to participants now and 24 have results posted.

Phase 1 5Phase 2 3Phase 3 14Phase 4 3No phase 2(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Study to Evaluate Immunogenicity, Safety, and Tolerability of ZOSTAVAX™ Vaccine (Zoster Vaccine Live, V211) Administered Concomitantly Versus Nonconcomitantly With Quadrivalent Influenza Virus Vaccine (Inactivated) in Participants ≥50 Years of Age (V211-062)CompletedNCT02519855Phase 3Results posted
• ZOSTAVAX™ Safety and Immunogenicity in Korean Adults (V211-034)CompletedNCT01556451Phase 4Results posted
• A Study to Evaluate the Safety and Immunogenicity of Inactivated Varicella Zoster Virus (VZV) Vaccine in Adults With Autoimmune Disease (V212-009)CompletedNCT01527383Phase 2Results posted
• Safety, Tolerability, and Immunogenicity of Zoster Vaccine Live (ZOSTAVAX™) in Healthy Adults in India (V211-025)CompletedNCT01527370Phase 3Results posted
• Safety and Immunogenicity of Zoster Vaccine (ZOSTAVAX™) Made With an Alternative Manufacturing Process (AMP) (V211-042 AM1)CompletedNCT01505647Phase 3Results posted
• A Study to Evaluate the Safety and Immunogenicity of Inactivated Varicella-Zoster Virus (VZV) Vaccine in Adults With Hematologic Malignancies (HM) Receiving Treatment With Anti-Cluster of Differentiation (CD) 20 Monoclonal Antibodies (V212-013)CompletedNCT01460719Phase 1Results posted
• Immunogenicity and Safety Study of ZOSTAVAX Administered by Intramuscular or Subcutaneous Route to Participants Aged From 50 Years Old (V211-045)CompletedNCT01391546Phase 3Results posted
• A Study of Intradermal Administration of ZOSTAVAX™ (V211-051 AM2)CompletedNCT01385566Phase 1Results posted
• A Study to Evaluate the Safety and Efficacy of Inactivated Varicella-zoster Vaccine (VZV) as a Preventative Treatment for Herpes Zoster (HZ) and HZ-related Complications in Adult Participants With Solid Tumor or Hematologic Malignancy (V212-011)CompletedNCT01254630Phase 3Results posted
• Safety, Tolerability, and Immunogenicity of a Booster Dose of Zoster Vaccine, Live (V211-029)CompletedNCT01245751Phase 3Results posted
• A Study to Evaluate the Safety and Efficacy of Inactivated Varicella-zoster Vaccine (VZV) as a Preventative Treatment for Herpes Zoster (HZ) and HZ-related Complications in Participants Undergoing Hematopoietic Cell Transplants (HCTs) (V212-001)CompletedNCT01229267Phase 3Results posted
• A Study to Evaluate Long-term Impact of VARIVAX Among Children and Adolescents (V210-036)(COMPLETED)CompletedNCT01077804Results posted
• A Study to Evaluate Immunity to Varicella Zoster Virus After Immunization With V212 Vaccine or Zostavax (V212-003)CompletedNCT00886613Phase 1Results posted
• A Study to Test the Safety and Antibody Response of V212 in Healthy Adults (V212-004)(COMPLETED)CompletedNCT00696709Phase 1Results posted
• Zostavax® at Minimum Release Specification Approaching Expiry (V211-044)CompletedNCT00681031Phase 4Results posted
• Immunogenicity and Safety of a 1-dose Regimen of a Zoster Vaccine Versus Different 2-dose Regimens in Participants ≥ 70 Years of Age. (V211-043)CompletedNCT00561080Phase 3Results posted
• ZOSTAVAX™ Safety Study in Subjects ≥ 60 Years of Age (V211-020)CompletedNCT00550745Phase 4Results posted
• ZOSTAVAX™ in Patients on Chronic/Maintenance Corticosteroids (V211-017) (COMPLETED)CompletedNCT00546819Phase 2Results posted
• ZOSTAVAX™ Administered Concomitantly With PNEUMOVAX™ 23 (V211-012)(COMPLETED)CompletedNCT00535730Phase 3Results posted
• A Study of an Investigational V212/Heat-Treated Varicella-Zoster Virus (VZV) Vaccine in Immunocompromised Adults (V212-002)CompletedNCT00535236Phase 1Results posted
• Study to Evaluate the Safety and Effectiveness of Zostavax™ in Subjects 50 - 59 Years of Age (V211-022)CompletedNCT00534248Phase 3Results posted
• A Study of an Investigational Zoster Vaccine, in Subjects With a History of Herpes Zoster (V211-014)CompletedNCT00322231Phase 3Results posted
• A Study of an Investigational Zoster Vaccine in Subjects With a History of Varicella (Chickenpox) Given Concomitantly With Another Vaccine (V211-011)CompletedNCT00231816Phase 3Results posted
• A Study to Evaluate Safety, Tolerability, and Immunogenicity of an Investigational Zoster Vaccine In Subjects With a History of Varicella (Chickenpox)(V211-010)(COMPLETED)CompletedNCT00130793Phase 3Results posted
• A Lot-to-Lot Consistency Study to Evaluate Safety, Tolerability, and Immunogenicity of Inactivated Varicella Zoster Virus (VZV) Vaccine in Healthy Adults (V212-014)WithdrawnNCT02180295Phase 3
• ZOSTAVAX™ (Zoster Vaccine Live) Long-term Effectiveness Study (V211-024)CompletedNCT01600079
• Safety, Tolerability, and the Body's Ability to Develop Resistance to an Investigational Vaccine for Shingles (V211-007)CompletedNCT00109122Phase 2