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Enrolling by invitationNCT06925685Updated Oct 23, 2026

Follow-Up for Study Participants Treated With an Allogeneic CAR T Cell Product

An observational study in Hematologic Malignancies and Solid Tumors, sponsored by Allogene Therapeutics. Enrolling by invitation at 1 site in United States. Per ClinicalTrials.gov, last updated 2026-10-23.

Sponsored by Allogene Therapeutics · Observational

Updated Oct 23, 2026Title changedGo to Updates ↓
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
50
Sex
All
01

Study summary

An observational, long-term follow up (LTFU) study of participants who received an allogeneic CAR T product in a prior clinical study. Participants will be followed for 15 years after their last infusion of an allogenic CAR T cell product.

02

Conditions studied

  • Hematologic Malignancies
  • Solid Tumors

Keywords

  • CAR T
  • Allogeneic CAR T
  • long term follow up
03

In context

Hematologic Neoplasms

1,444 studies on the registry are indexed under Hematologic Neoplasms; 420 are open to participants now.

This study's planned enrollment of 50 is below the median of 186 across 322 observational studies indexed under Hematologic Neoplasms.

Browse Hematologic Neoplasms studies →

Lead sponsor

Allogene Therapeutics is the lead sponsor of 9 studies on the registry; 3 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Participants who have received an allogeneic CAR T-cell product.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Received an allogenic CAR T-cell product infusion to treat an oncologic condition in a previous Allogene or Servier sponsored clinical study

Exclusion criteria

Exclusion Criteria:

  • Less than 12 months of follow up after the last allogeneic CAR T-cell product, unless approved by the Allogene Medical Monitor
05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
50 participants (estimated)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Incidence of delayed adverse events potentially related to allogeneic CAR T-cell product and allogeneic CAR T-cell product-related SAEs

    Time frame: Up to 15 years post treatment with allogeneic CAR T-cell product

  2. Overall survival (OS)

    Time frame: Up to 15 years post treatment with allogeneic CAR T cell product

  3. Presence of replication competent lentivirus (RCL) in blood

    Time frame: Up to 15 years post treatment with allogeneic CAR T cell product

07

Study locations

1 site
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

1 registry update since Sep 25, 2026
Title
Follow-Up for Study Participants Treated With an Allogeneic CAR T- Cell Product
Oct 23, 2026
Show all 1 update
  1. Oct 23, 2026
    Title Follow-Up for Study Participants Treated With an Allogeneic CAR T- Cell Product
    + 4 other changes: index terms, verification date, oversight details and contact details

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT06925685
Lead sponsor
Allogene Therapeutics
Responsible party
Sponsor
First posted
Apr 13, 2025
Start date
Jan 31, 2025
Primary completion
Jan 2039 (estimated)
Completion
Jan 2039 (estimated)
Last update
Oct 23, 2026

Study contacts

Allogene Study Director
study director · Allogene Therapeutics, Inc

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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No contact was published for this record. The registry link below has the sponsor’s details.

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