St. Jude Children's Research Hospital: Hematologic Neoplasms trials

The registry lists 32 Hematologic Neoplasms studies with St. Jude Children's Research Hospital as lead sponsor. 6 are open to participants now and 9 have results posted.

Phase 1 10Phase 2 11Phase 3 2No phase 9(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and LymphomaRecruitingNCT07257419Phase 1
• TCRαβ-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic MalignanciesRecruitingNCT07052370Phase 1
• Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell TherapyRecruitingNCT06579469
• CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological MalignanciesRecruitingNCT06326463Phase 1
• Long-term Follow-up After Adoptive Transfer of Genetically Modified Cell ProductsRecruitingNCT05713214
• Response to Influenza Vaccination in Pediatric Oncology PatientsRecruitingNCT05384288
• Pediatric Study of GVHD Ppx w/o Calcineurin Inhibitors After Day60 Post First Allo HSCT for Hematological Malignancies.TerminatedNCT05579769Phase 2Results posted
• Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger PatientsTerminatedNCT02433483Phase 2Results posted
• Bortezomib and Vorinostat in Younger Patients With Refractory or Relapsed MLL Rearranged Hematologic MalignanciesTerminatedNCT02419755Phase 2Results posted
• Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior TransplantationTerminatedNCT02259348Phase 2Results posted
• Combined T Cell Depleted Haploidentical Peripheral Blood Stem Cell and Unrelated Umbilical Cord Blood Transplantation in Patients With Hematologic Malignancies Using a Total Lymphoid Irradiation Based Preparative RegimenTerminatedNCT02199041Phase 2Results posted
• Haploidentical Donor Hematopoietic Progenitor Cell and NK Cell Transplantation for Hematologic MalignancyCompletedNCT01807611Phase 2Results posted
• T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic TransplantTerminatedNCT01621477Phase 2Results posted
• Umbilical Cord Blood Transplantation In Patients With Hematologic Malignancies Using A Myeloablative Preparative RegimenCompletedNCT01328496Phase 2Results posted
• HLA-Nonidentical Stem Cell and Natural Killer Cell Transplantation for Children Less the Two Years of Age With Hematologic MalignanciesCompletedNCT00145626Phase 2Results posted
• Evaluating Immune Response to COVID-19 Vaccines in Patients With Cancer, Transplant or Cellular Therapy RecipientsCompletedNCT05164016
• The Oronasal Microbiota in Pediatric Oncology PatientsCompletedNCT02949427
• Analysis of T Cell and Natural Killer (NK) Cell in Relation to Viral Infections in Pediatric Stem Cell Transplant Patients and DonorsCompletedNCT02301065
• Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic MalignanciesCompletedNCT02270788Phase 1
• The Good Patient StudyCompletedNCT02199548
• Bendamustine Hydrochloride, Clofarabine, and Etoposide in Treating Younger Patients With Relapsed or Refractory Hematologic MalignanciesCompletedNCT01900509Phase 1
• Sorafenib in Combination With Cytarabine and Clofarabine in Patients With Refractory or Relapsed Hematologic MalignanciesCompletedNCT00908167Phase 1
• Haploidentical Hematopoietic Stem Cell Transplantation Using A Novel Clofarabine Containing Conditioning Regimen For Patients With Refractory Hematologic MalignanciesCompletedNCT00824135Phase 1
• AVN of Weight-Bearing Joints In Patients With Hematologic Malignancies Treated With Dexamethasone Or PrednisoneCompletedNCT00719147
• Irinotecan, Vincristine, and Dexamethasone In Children With Relapsed And/Or Refractory Hematologic MalignanciesCompletedNCT00718757Phase 1
• Pilot Study of Haploidentical Natural Killer Cell Infusions for Poor Prognosis Non-AML Hematologic MalignanciesCompletedNCT00697671Phase 1
• Long Term Follow Up Of Patients Who Have Received Gene Therapy Or Gene Marked ProductsCompletedNCT00695279
• Pilot Study of Expanded, Donor Natural Killer Cell Infusions for Refractory Non-B Lineage Hematologic Malignancies and Solid TumorsCompletedNCT00640796Phase 1
• Haploidentical Stem Cell Transplantation for Patients With Hematologic MalignanciesCompletedNCT00186823Phase 3
• Stem Cell Transplantation for Patients With Hematologic MalignanciesCompletedNCT00152139Phase 3
• Haploidentical Stem Cell Transplant for Treatment Refractory Hematological MalignanciesCompletedNCT00145613Phase 2
• Stem Cell Transplantation as Immunotherapy for Hematologic MalignanciesCompletedNCT00143559Phase 2