Hematologic Diseases clinical trials
The registry lists 609 studies for Hematologic Diseases across more than 10 countries. 108 are recruiting or about to start. 169 of them are mainly about Hematologic Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 122 narrower conditions too, such as Multiple Myeloma: 22,904 studies, 4,786 open.
ClinicalTrials.gov finds 22,479 studies for Hematologic Diseases. How that becomes 609 here
This page counts the studies the registry files under Hematologic Diseases, and those it files under no condition that list Hematologic Diseasesthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 22,479Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −21,248Filed under a narrower condition, counted on its own pageMultiple Myeloma 3,618 · Leukemia, Myeloid, Acute 3,205 · Precursor Cell Lymphoblastic Leukemia-Lymphoma 1,596 · Anemia 1,520 · Leukemia 1,171 · Leukemia, Lymphocytic, Chronic, B-Cell 1,028 · 104 more
- −1List Hematologic Diseases as a condition, but the registry did not file them under itMost often written as “Malignant Hematological Diseases” (1). The registry filed them under other conditions only, most often Bronchiolitis Obliterans Syndrome (1).
- −621Match it another way15 name it in the title, 1 in a keyword, and 605 by a synonym or other text the search reads.
- 609The count on this page6 of them list Hematologic Diseases in their own words; the registry filed them under no condition.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
National Heart, Lung, and Blood Institute (NHLBI) (42) · Seagen Inc. (30) · M.D. Anderson Cancer Center (14) · National Center for Research Resources (NCRR) (12) · Novartis Pharmaceuticals (11) · BioMarin Pharmaceutical (8) · Nanfang Hospital, Southern Medical University (7) · Pfizer (7)
What is being tested here
Drugs under test in Hematologic Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Cyclophosphamide | 4 | 1 | 18 |
| Dexamethasone | 4 | 1 | 7 |
| Fludarabine | 3 | 0 | 10 |
| Busulfan | 2 | 1 | 10 |
| Lenalidomide | 2 | 3 | 8 |
| Exagamglogene autotemcel | 2 | 6 | 6 |
| Daratumumab | 2 | 0 | 2 |
| Pomalidomide | 2 | 0 | 2 |
| Mezagitamab | 2 | 2 | 2 |
| Fludarabine phosphate | 2 | 0 | 2 |
Drug classes tested here Alkylating agents 4 open · Corticosteroids 4 open · Tyrosine kinase inhibitors (TKIs) 3 open · Antimetabolites 3 open · JAK inhibitors 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026A Study Investigating Intravenous Human Normal Immunoglobulin 10% in Adults With Chronic Immune Thrombocytopenia (ITP) · Phase 3 · Kedrion S.p.A.
- Mar 2027Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia · Phase 3 · Quetzal Therapeutics
- Jun 2027Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Severe Sickle Cell Disease (SCD) · Phase 3 · Vertex Pharmaceuticals Incorporated
- Jun 2027Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease · Phase 3 · Vertex Pharmaceuticals Incorporated
- Aug 2027Study With Elranatamab Versus Lenalidomide in Patients With Newly Diagnosed Multiple Myeloma After Transplant · Phase 3 · Pfizer
- Oct 2027A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) · Phase 3 · Loxo Oncology, Inc.
- Nov 2027Study of BTK Inhibitor LOXO-305 Versus Approved BTK Inhibitor Drugs in Patients With Mantle Cell Lymphoma (MCL) · Phase 3 · Loxo Oncology, Inc.
- Nov 2027A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study) · Phase 3 · Taiho Oncology, Inc.
- Nov 2027Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Transfusion-Dependent β-Thalassemia (TDT) · Phase 3 · Vertex Pharmaceuticals Incorporated
- Nov 2026Muscle Dysfunction in Patients With Hematological Diseases Referred to Stem Cell Transplant · Rigshospitalet, Denmark
Who these studies take
Of the 72 Hematologic Diseases studies recruiting now, 46 (64%) set no upper age limit and 22 (31%) stop at 75 or younger. 27 (38%) take children under 18. 1 (1%) are for women only and 2 (3%) for men only; 4 (6%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 18 (25%) | 19 (26%) |
| 18 | 68 (94%) | 69 (96%) |
| 30 | 66 (92%) | 67 (93%) |
| 40 | 62 (86%) | 63 (88%) |
| 50 | 61 (85%) | 62 (86%) |
| 65 | 57 (79%) | 57 (79%) |
| 75 | 52 (72%) | 52 (72%) |
| 85 | 48 (67%) | 48 (67%) |
Across all 609 studies, recruiting or not: 31% stop at 75 or younger and 22% at 65; 42% take children; 1% are for women only and 7% for men only; 7% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hematologic Diseases studies take
Of 49 phase 3 interventional studies under Hematologic Diseases, half reached primary completion within 37 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 26 mo16–74 · 33 studies | — | — |
| Phase 2 | 47 mo33–94 · 41 studies | — | — |
| Phase 3 | 37 mo25–66 · 49 studies | 37 mo25–66 · 44 studies | — |
| Interventional, no phase | 37 mo22–47 · 54 studies | — | 37 mo22–49 · 51 studies |
| Observational | 51 mo16–78 · 64 studies | — | 45 mo13–190 · 47 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting2
- A Phase 1/2 Study to Evaluate the Safety and Efficacy of Dibotatug (DR-01) in Adults With Bone Marrow Failure SyndromesNov 4, 2026NCT07712562
- Role of Viscoelastometric Testing in the Development and Validation of a Clinical-biological Score for Predicting Bleeding in Patients With Malignant Haematological Disorders and Severe ThrombocytopeniaOct 22, 2026NCT07653672
Stopped2
- Open-Label Extension Study to Pioneer Study 6058-SCD-101TerminatedOct 28, 2026NCT07401823
- AZA + Venetoclax as Maintenance Therapy in Patients With AML in RemissionTerminatedOct 16, 2026NCT04062266
Newly registered5
- A Study to Assess the Pharmacokinetics and Safety of Revumenib in Participants With Advanced Cancer and Hepatic or Renal ImpairmentNov 6, 2026NCT07923071
- Romiplostim for Platelet Engraftment After Haploidentical or Matched Unrelated Donor Allogeneic Hematopoietic Stem Cell TransplantationNov 5, 2026NCT07919977
- Phase 2 Study of Oral Epetraborole in Adults With Polycythemia VeraOct 23, 2026NCT07891533
- Symptom Monitoring and Management Intervention After CAR-TOct 21, 2026NCT07886190
- Study of Anxiety and Depression in Patients With Hematologic MalignanciesOct 20, 2026NCT07883070
Studies
Recruiting first, then most recently updated. Showing 50 of 609. Browse all 609 → or search them.
- A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)RecruitingNCT06439082Phase 35 countries
- Screening for Hematology Branch ProtocolsEnrolling by invitationNCT000016201 country
- Romiplostim for Platelet Engraftment After Haploidentical or Matched Unrelated Donor Allogeneic Hematopoietic Stem Cell TransplantationRecruitingNCT07919977Phase 21 country
- A Study to Assess the Pharmacokinetics and Safety of Revumenib in Participants With Advanced Cancer and Hepatic or Renal ImpairmentNot yet recruitingNCT07923071Phase 1
- Harmony-HHT: ATV-1601 in Participants With Hereditary Hemorrhagic Telangiectasia (HHT)RecruitingNCT07601425Phase 1/22 countries
- Study of Anxiety and Depression in Patients With Hematologic MalignanciesRecruitingNCT078830701 country
- Bispecific CD19/CD20-Targeted Chimeric Antigen Receptor (CAR) Modified T Cells With 4-1BB and Mutated CD28 Costimulatory Domains in Patients With Relapsed or Refractory CD19+ Hematologic MalignanciesNot yet recruitingNCT07701889Phase 11 country
- A Phase 1/2 Study to Evaluate the Safety and Efficacy of Dibotatug (DR-01) in Adults With Bone Marrow Failure SyndromesRecruitingNCT07712562Phase 1/21 country
- A Study of Mezagitamab in Adults With Chronic Primary Immune ThrombocytopeniaRecruitingNCT06722235Phase 318 countries
- Efficacy and Safety of SIL-8301 for Control of Hemolysis in a Uniform Sickle Cell Disease EndotypeRecruitingNCT07282210Phase 21 country
- A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune ThrombocytopeniaRecruitingNCT06948318Phase 315 countries
- Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic LeukemiaRecruitingNCT07504458Phase 35 countries
- Alpha/Beta T-cell Depleted Blood-forming Stem Cell Transplant From Related or Unrelated Donors for Blood Diseases in Children and Young AdultsRecruitingNCT04806347Phase 11 country
- HEME Home Transfusion ProgramRecruitingNCT06487247Not applicable1 country
- Phase 2 Study of Oral Epetraborole in Adults With Polycythemia VeraNot yet recruitingNCT07891533Phase 21 country
- Symptom Monitoring and Management Intervention After CAR-TNot yet recruitingNCT07886190Not applicable1 country
- Role of Viscoelastometric Testing in the Development and Validation of a Clinical-biological Score for Predicting Bleeding in Patients With Malignant Haematological Disorders and Severe ThrombocytopeniaRecruitingNCT076536721 country
- A Study Investigating Intravenous Human Normal Immunoglobulin 10% in Adults With Chronic Immune Thrombocytopenia (ITP)RecruitingNCT07059000Phase 38 countries
- Therapeutic RSK1 Targeting in Myeloid MalignanciesRecruitingNCT07379125Phase 11 country
- Leading in MPNs Beyond Ruxolitinib in Combo With T-RegsRecruitingNCT05423691Phase 11 country
- Data Collection of Standard Care and Evaluation of NHLBI Patients and DonorsEnrolling by invitationNCT044509271 country
- Early Use of Tacrolimus in HLA-Mismatched Haploidentical Allogeneic Hematopoietic Transplantation With Post-Transplant CyclophosphamideRecruitingNCT06828796Phase 21 country
- A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)RecruitingNCT04256317Phase 2/310 countries
- Outcome of HSCT in Children at Ramathibodi HospitalRecruitingNCT078577461 country
- Study on the Clinical Efficacy of Teclistamab and TalquetamabRecruitingNCT064777831 country
- Multidisciplinary Intervention for Adults With Chronic Graft-versus-host DiseaseRecruitingNCT06910969Not applicable1 country
- Treatment of Hemophilia A Patients With FVIII InhibitorsRecruitingNCT040230192 countries
- (Apex) Bezuclastinib in Patients With Advanced Systemic MastocytosisRecruitingNCT04996875Phase 214 countries
- Study to Characterize Mismatched to Fully HLA-Matched Ossium HPC, Marrow and Living Donor Transplantation in Patients With Hematologic MalignanciesNot yet recruitingNCT07710781Not applicable
- Immersive Virtual Reality Applied to Therapeutic Physical Exercise in Cellular TherapyNot yet recruitingNCT07679958Not applicable1 country
- A Dietitian-Driven Unified Nutritional Care Model (ADDUCE)RecruitingNCT07730996Not applicable1 country
- A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple MyelomaRecruitingNCT07075185Phase 12 countries
- Reconstruction Kinetics of γδ T Cells After Unrelated Cord Blood TransplantationRecruitingNCT077826841 country
- Visual and Auditory Distraction for the Relief of Pain and AnxietyEnrolling by invitationNCT07023692Not applicable1 country
- ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic DisordersRecruitingNCT043986281 country
- A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)RecruitingNCT05254743Phase 323 countries
- A Long-term Follow-up Study in Participants Who Received CTX001Enrolling by invitationNCT04208529Phase 36 countries
- Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic SyndromeRecruitingNCT07216443Phase 21 country
- Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)RecruitingNCT01666080Not applicable1 country
- Human Leukocyte Antigen (HLA) Mismatched Unrelated Allogeneic Hematopoietic Stem Cell TransplantationRecruitingNCT06809712Phase 11 country
- Frailty in the Elderly Oncological and Oncohematological Patient.Enrolling by invitationNCT076243701 country
- CHAPTER: Clonal Haematopoiesis Assessment: Prevention, Treatment and ResearchRecruitingNCT073130591 country
- The Implementation of the Go Wish Game to Promote Advance Care Planning in Onco- Hematologic DiseaseRecruitingNCT06795815Not applicable1 country
- Fertility in Young Adults Who Did (Not) Store Testicular Tissue Before a Treatment Leading to Fertility ProblemsEnrolling by invitationNCT04202094Not applicable1 country
- Amphotericin B for Breakthrough Fungal Infections After Triazole Prophylaxis in Hematological PatientsNot yet recruitingNCT07559032Not applicable1 country
- Clinical Study on the Preservation of Ovarian Function Following Hematopoietic Stem Cell Transplantation in Patients With Malignant Hematologic Diseases Using GoserelinNot yet recruitingNCT07552480Not applicable1 country
- Autologous Testicular Tissue TransplantationRecruitingNCT05414045Not applicable1 country
- ATHNdataset RegistryRecruitingNCT068205151 country
- Complementary and Alternative Medicine Among Patients With Hematologic Malignancies in FranceNot yet recruitingNCT07541326Not applicable1 country
- Diamond Blackfan Anemia Registry (DBAR)RecruitingNCT001060151 country