M.D. Anderson Cancer Center: Hematologic Neoplasms trials

The registry lists 80 Hematologic Neoplasms studies with M.D. Anderson Cancer Center as lead sponsor. 21 are open to participants now and 16 have results posted.

Early Phase 1 3Phase 1 19Phase 2 25Phase 3 3Phase 4 4No phase 33(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Bone Marrow Imaging and Clinical Outcomes Across Hematologic, Oncologic, and Other Relevant ConditionsRecruitingNCT07743476
• Phase II Study of CD5 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Aggressive T Cell Hematological MalignanciesNot yet recruitingNCT07137481Phase 2
• Optimized Cord Blood Transplantation for the Treatment of Patients With High-risk Hematologic Malignancies Who Have Relapsed After First Allogeneic Stem Cell TransplantationRecruitingNCT06807606Phase 2
• Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural EffusionRecruitingNCT06184321Early Phase 1
• Phase II Study of Pirtobrutinib With Venetoclax In Relapsed-Refractory MCL (Mantle Cell Lymphoma) PatientsRecruitingNCT05529069Phase 2
• Phase I/II Study of CD5 CAR Engineered IL15-Transduced Cord Blood-Derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed/Refractory Hematological MalignancesRecruitingNCT05110742Phase 1/2
• Complications and Clinical Response in Cancer Patients Treated With Anti-VEGF-Related TherapiesRecruitingNCT05108519
• Formulating Expert Consensus Guidelines in Cancer Care Using the Delphi MethodRecruitingNCT05054413
• The Impact of COVID-19 on Pulmonary ProceduresRecruitingNCT05022446
• Neurocognitive Outcomes After Whole Brain Radiation Therapy for Hematologic MalignanciesRecruitingNCT05011045
• Impact of Project ECHO on Improving the Quality of Palliative Care in Patients With Advanced Cancer and Their Caregivers in Underserved Areas of Kenya, Nigeria, Ghana, South Africa, India, and EthiopiaRecruitingNCT04984551Phase 2
• Outcomes After Chimeric Antigen Receptor Therapy and Radiation Therapy for Hematologic MalignanciesRecruitingNCT04888338
• Adoption of Audio Recording in the Outpatient Supportive Care CenterNot yet recruitingNCT04871477
• Expressive Writing for the Management of Stress in Cancer SurvivorsRecruitingNCT04776941Not applicable
• Addition of Cord Blood Tissue-Derived Mesenchymal Stromal Cells to Ruxolitinib for the Treatment of Steroid-Refractory Acute Graft Versus Host DiseaseRecruitingNCT04744116Early Phase 1
• Baloxavir and Oseltamivir for the Treatment of Severe Influenza Infection in Immunocompromised PatientsRecruitingNCT04712539Phase 2
• The Effect of COVID-19 Pandemic on Adolescent and Young Adult Cancer Patients and SurvivorsRecruitingNCT04551378
• Donor T Cell Therapy in Treating Immunocompromised Patients With Adenovirus-Related DiseaseRecruitingNCT03425526Phase 1
• Non-invasive Ventilation in Reducing the Need for Intubation in Patients With Cancer and Respiratory FailureRecruitingNCT02464696Not applicable
• Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy ProgramRecruitingNCT01772771
• Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated With Proton TherapyRecruitingNCT00991094
• PHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONINCompletedNCT04983901Phase 2Results posted
• Omacetaxine and Venetoclax for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Harboring Mutant RUNX1TerminatedNCT04874194Phase 1/2Results posted
• Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain MetastasesTerminatedNCT04789668Phase 1/2Results posted
• An Open-label Phase II Study of Lorvotuzumab MertansineCompletedNCT02420873Phase 2Results posted
• Haloperidol and Lorazepam for Delirium in Patients With Advanced CancerActive, not recruitingNCT01949662Phase 2Results posted
• CMC-544 and Allogeneic Transplantation for CD22 Positive-Lymphoid MalignanciesCompletedNCT01664910Phase 1/2Results posted
• Cognitive Behavioral Therapy and Multimodal Therapy in Treating Sleep Disturbance in Patients With CancerActive, not recruitingNCT01628029Phase 2Results posted
• Mismatched Transplantation Using High-dose Post-transplant CyclophosphamideCompletedNCT01010217Phase 2Results posted
• Prevention of Osteoporosis in Bone Marrow Transplantation (BMT) PatientsCompletedNCT00824993Phase 3Results posted
• Oral Posaconazole Three Times Per Day vs Weekly High Dose Amphotericin B Lipid Complex (ABLC)CompletedNCT00750737Phase 3Results posted
• INCB018424 in Patients With Advanced Hematologic MalignanciesCompletedNCT00674479Phase 2Results posted
• Thymoglobulin, Sirolimus and Mycophenolate Mofetil for Prevention of Acute Graft-Versus-Host Disease (GVHD)TerminatedNCT00506948Phase 2Results posted
• Phase I/II Trial of Fludarabine Plus Busulfan and Allogeneic Progenitor Cell SupportCompletedNCT00506857Phase 1/2Results posted
• Fatigue in Emergency Center PatientsTerminatedNCT00504985Results posted
• Intermittent Use of Aerosolized Ribavirin for Treatment of RSVCompletedNCT00500578Phase 4Results posted
• Voraxaze for Delayed Methotrexate ClearanceTerminatedNCT00424645Phase 1/2Results posted
• Feasibility of the Use of Weighted Blankets to Improve Sleep Among Patients With Hematological MalignanciesActive, not recruitingNCT06584955Not applicable
• Survey Assessment of Patient and Provider Impressions of Telemedicine in Radiation OncologyActive, not recruitingNCT05496972
• Patient Perceptions of the Relational Empathy of Healthcare Practitioners From the Department of Emergency Medicine During the COVID-19 PandemicActive, not recruitingNCT05102656Not applicable
• Study Assessing the Feasibility, Safety and Efficacy of Genetically Engineered Glucocorticoid Receptor Knock Out Virus Specific CTL Lines for Viral Infections in Immunosuppressed Cancer PatientsTerminatedNCT05101213Phase 1
• Assessment of Verbal Comprehension and Cognitive Processes in Patients Admitted to the Palliative and Supportive Care UnitSuspendedNCT05091632
• Distress Associated with Coronavirus Disease 2019 and Telehealth on Supportive Care Patients with Advanced CancerCompletedNCT05058339
• Parental Attitudes and Beliefs Regarding Risks Associated With Opioid Use in Children With CancerActive, not recruitingNCT05055011
• Impact of Aminoglycosides in Hypotensive Septic Oncology PatientsCompletedNCT05045963
• Patient Reported Symptom Control With THC or CBD UseActive, not recruitingNCT04875286
• Positive Activities Intervention to Improve Quality of Life in Collectivist Culture Cancer Patients and Their CaregiversCompletedNCT04810052Not applicable
• Pegloticase for the Reduction of Uric Acid in Patients With Tumor Lysis SyndromeCompletedNCT04745910Phase 4
• Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health OutcomesActive, not recruitingNCT04743466
• Exercise Program (TEAM Me) for the Improvement of Movement and Mobility in Pediatric and Adolescent and Young Adult Patients With Cancer Undergoing a Blood Stem Cell TransplantActive, not recruitingNCT04678427Not applicable
• Well-being in Cancer Patients With Neuropathy During COVID-19 Who Participated in Prior Clinical TrialsActive, not recruitingNCT04650178
• Financial Toxicity in Cancer PatientsActive, not recruitingNCT04592250
• Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment of Moderate, Severe or Critical PneumoniaActive, not recruitingNCT04565665Phase 1/2
• Duloxetine and Neurofeedback Training for the Treatment of Chemotherapy Induced Peripheral NeuropathyActive, not recruitingNCT04560673Phase 2
• Major Complication Rate in Cancer Patients With Neutropenic Fever Potentially Eligible for a Hospital at Home ProgramWithdrawnNCT04557709
• Well-Being and Health-Related Quality of Life in Cancer Patients and Survivors During the COVID-19 PandemicActive, not recruitingNCT04500600
• Effect of Opioid Infusion Rate on Abuse Liability Potential of Intravenous Hydromorphone for Cancer PainActive, not recruitingNCT04296305Phase 4
• Telementoring Intervention (ECHO) for the Transformation of Professional Engagement, Practice Efficiency, and Community Building Through Team Meetings in Diagnostic Imaging CliniciansActive, not recruitingNCT04196972Not applicable
• Fentanyl Buccal Tablet or Morphine for Exertional Dyspnea in Cancer PatientsActive, not recruitingNCT04188418Phase 3
• Levorphanol as a Second Line Opioid in Reducing Pain in Patients With CancerTerminatedNCT03579446Early Phase 1
• Comprehensive Nutritional Geriatric Assessments in Identifying Malnutrition in Older Cancer ParticipantsActive, not recruitingNCT03035604
• Gardasil 9 Vaccine in Preventing HPV Infection in Patients With Hematologic Malignancies Undergoing Donor Stem Cell TransplantActive, not recruitingNCT03023631Phase 4
• Donor Bone Marrow Derived Mesenchymal Stem Cells in Controlling Heart Failure in Patients With Cardiomyopathy Caused by AnthracyclinesSuspendedNCT02962661Phase 1
• Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell TransplantActive, not recruitingNCT02861417Phase 2
• Phase II Study of Fludarabine, Cytarabine (ARA-C) and Erwinase IV in Patients With Relapsed or Refractory Hematologic MalignanciesWithdrawnNCT02718755Phase 2
• Salvage Radiation Therapy in Treating Patients With Metastatic Cancer That Has Progressed After Systemic ImmunotherapyCompletedNCT02710253Phase 2
• Hu8F4 in Treating Patients With Advanced Hematologic MalignanciesActive, not recruitingNCT02530034Phase 1
• Preliminary Testing of the MD Anderson Symptom Inventory (Adolescent Version)Active, not recruitingNCT02515383
• Donor Cytomegalovirus-Specific Cytotoxic T-Lymphocytes in Treating Patients With a Persistent Cytomegalovirus InfectionActive, not recruitingNCT02210078Phase 2
• Donor Cord Blood T-Cell Infusion After Stem Cell Transplant in Treating Patients With Relapsed Hematological MalignanciesTerminatedNCT01630564Phase 1
• Cord Blood Fucosylation to Enhance Homing and Engraftment in Patients With Hematologic MalignanciesCompletedNCT01471067Phase 1
• 4'-Thio-araC (Thiarabine) in Advanced Hematologic MalignanciesCompletedNCT01139151Phase 1
• FTS Study in Patients With Advanced Hematologic MalignanciesCompletedNCT00867230Phase 1
• Cloretazine (VNP40101M) With Hematopoietic Cell Transplantation for Hematologic MalignanciesCompletedNCT00521859Phase 1
• Collection of Outcomes Data for Pregnant Patients With CancerTerminatedNCT00507572
• Phase I Study of Continuous Infusion Schedule of FMdC in Hematologic MalignanciesCompletedNCT00061620Phase 1
• Study of ABT-751 in Patients With Refractory Hematologic MalignanciesCompletedNCT00047489Phase 1
• IUdR/BUdR Cell Cycle LabellingCompletedNCT00042250Not applicable
• Phase II Study Of Roferon and Accutane For Patients With T-Cell MalignanciesCompletedNCT00038376Phase 2
• Clofarabine in Chronic Lymphocytic LeukemiaCompletedNCT00028418Phase 1