Head and Neck Neoplasms: all 2,403 studies

Page 6 of 25. Open to participants first (559), then studies with results posted, then the rest; newest registration first within each.

• EXCEL: Exercise for Cancer to Enhance Living WellRecruitingNCT04478851Not applicable
• Testing Less Intensive Radiation With Chemotherapy to Treat Low-risk Patients With HPV-positive Oropharyngeal CancerRecruitingNCT04444869Phase 2
• Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Head and Neck CancerRecruitingNCT04431648Phase 1
• Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid TumorsRecruitingNCT04429542Phase 1
• Pilot Study to Evaluate Photoacoustic Imaging in Head and Neck CancerRecruitingNCT04428515
• A Study of Concomitant Camrelizumab With Chemoradiation for Locally Advanced Head and Neck CancerNot yet recruitingNCT04405154Phase 2
• X-ray Psoralen Activated Cancer Therapy in Head and Neck, Breast, Sarcoma and MelanomaRecruitingNCT04389281Phase 1
• Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid TumorsRecruitingNCT04354064
• Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible SensitivityRecruitingNCT04273061Phase 2
• Telemedicine Nurse-Led Intervention for Rural Cancer SurvivorsNot yet recruitingNCT04267627Not applicable
• Surface Monitoring Technology to Remove The Mask - Stage 1RecruitingNCT04266223Not applicable
• Establishment of Squamous Cell Organoids of the Head and Neck to Assess Their Response to Innovative TherapiesRecruitingNCT04261192
• Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)RecruitingNCT04198766Phase 1/2
• Stereotactic Boost and Short-course Radiation Therapy for Oropharynx CancerRecruitingNCT04178174Phase 3
• Feasibility of Online MR-guided Radiotherapy on a 1.5T MR-LinacRecruitingNCT04172753Not applicable
• A Phase II Study on Adjuvant Vaccination with Dendritic Cells Loaded with Autologous Tumor Homogenate in Resected Stage IV Rare Cancers.RecruitingNCT04166006Phase 2
• Circulating Tumor DNA (ctDNA) in Locally Advanced Head and Neck Squamous Cell CarcinomaRecruitingNCT04099290
• The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac StudyRecruitingNCT04075305
• VoiceS: Voice Quality After Transoral CO2-Laser Surgery Versus Single Vocal Cord Irradiation for Larynx CancerRecruitingNCT04057209Not applicable
• Web-Based Program in Helping Patients With Head and Neck Cancer Adhere to Swallowing Exercises and Coping StrategiesRecruitingNCT04003051Phase 2
• DAHANCA 37. Re-irradiation With Proton RadiotherapyRecruitingNCT03981068Not applicable
• Deciphering Mechanisms Underlying Cancer ImmunogenicityRecruitingNCT03958240Not applicable
• IT or IA Infusion of PD1/PDL1/CTLA4 Inhibitors Versus IV for Immunotherapy of Head/Neck Cancers (HNC)RecruitingNCT03952065Phase 2/3
• Patient-Reported Outcomes in Head and Neck CancerRecruitingNCT03918382Not applicable
• EMST in Patients Undergoing CRT for HNCARecruitingNCT03916809Not applicable
• The Effects on Auditory Function of RADiotherapy and Chemotherapy Treatments for Head and Neck Tumours (EARAD)RecruitingNCT03914378
• Ultrasound Spectroscopy as Early Indicators of Radiation Treatment Response in Prostate, Rectum and Head & Neck CancersRecruitingNCT03908684
• Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell CarcinomaRecruitingNCT03875716Not applicable
• Trans-Artery/Intra-Tumor Infusion of Checkpoint Inhibitors Plus Chemodrug for Immunotherapy of Advanced Solid TumorsRecruitingNCT03755739Phase 2/3
• Liquid Biopsy Evaluation and Repository Development at Princess MargaretRecruitingNCT03702309
• Nutritional Course of Care After Surgical Treatment at the Patients Affected by a Cancer of the Head and by the NeckRecruitingNCT03632200Not applicable
• VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or LymphomaRecruitingNCT03556228Phase 1/2
• Sentinel. Ambulatory. Oral Cavity. Oropharynx (S.A.C.O)RecruitingNCT03545256Not applicable
• Concomitant Immune Check Point Inhibitor With Radiochemotherapy in Head And Neck CancerRecruitingNCT03532737Phase 2
• New MRI Biomarkers in Head and Neck CancersRecruitingNCT03483337
• Evaluation of an Oral Care Programme for Head and Neck Cancer PatientsRecruitingNCT03481647Not applicable
• SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and RegistryRecruitingNCT03452774
• Biospecimen Procurement for Head and Neck DisordersRecruitingNCT03429036
• De-escalation of Adjuvant Radio (Chemo) Therapy for HPV-positive Head-neck Squamous Cell CarcinomasRecruitingNCT03396718Not applicable
• StrataXRT vs Standard Clinical Practice for the Prevention of Acute Dermatitis in Head and Neck Cancers PatientsRecruitingNCT03394417Not applicable
• Salvage Brachytherapy and Hyperthermia for Recurrent H&N-tumoursRecruitingNCT03238378Not applicable
• Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Diagnosing Osteoradionecrosis in Patients With Head and Neck Cancer That Is Primary, Has Come Back, or Has Spread to Other Places in the BodyRecruitingNCT03145077Not applicable
• A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 RearrangementsRecruitingNCT03093116Phase 1/2
• Prospective Biobanking Study in Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself, Its Microenvironment and Immune Response (SCANDARE)RecruitingNCT03017573Not applicable
• Ontario-wide Cancer TArgeted Nucleic Acid EvaluationRecruitingNCT02906943
• Patient-derived Xenograft Models of Tumor From Patients With Head and Neck CancerRecruitingNCT02572778
• Head and Neck Cancer in Children: A Retrospective StudyRecruitingNCT02557048
• Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With PathologyRecruitingNCT02507141
• Standard Follow-up Program (SFP) for Head and Neck Cancer PatientsRecruitingNCT02435576
• Outcome Prediction in Head&Neck Cancer Patients After RadiotherapyRecruitingNCT01985984
• Prediction of Outcome After Chemoradiotherapy for Head and Neck Cancer Using Functional Imaging and Tumor BiologyRecruitingNCT01829646Not applicable
• Phase I Trial: T4 Immunotherapy of Head and Neck CancerRecruitingNCT01818323Phase 1
• Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"RecruitingNCT01365169Not applicable
• Impact of Selective Radiation Dose Escalation and Tumour Hypoxia Status on Locoregional Tumour Control After Radiochemotherapy of HNTRecruitingNCT01212354Phase 3
• Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal VolunteersRecruitingNCT00900419
• Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy ParticipantsRecruitingNCT00898638
• Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung CancersRecruitingNCT00568490
• Identification and Characterization of Novel Proteins and Genes in Head and Neck CancerRecruitingNCT00230308
• Molecular and Genomic Profiling of Head and Neck TumorsRecruitingNCT00200486
• Mental Health App for Cancer Survivors StudyTerminatedNCT06472726Not applicableResults posted
• Phase 1b Safety Study of Xevinapant, Weekly Cisplatin, and RT in Participants With Unresected LA SCCHN (HyperlynX)TerminatedNCT06056310Phase 1Results posted
• A Study of Tislelizumab in Combination With Investigational Agents in Participants With Head and Neck Squamous Cell CarcinomaCompletedNCT05909904Phase 2Results posted
• A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid TumorsTerminatedNCT05572684Phase 1/2Results posted
• Evaluation of a Cone-beam CT Scanner for Image Guided RadiotherapyCompletedNCT05524454Not applicableResults posted
• Phase III Xevinapant (Debio 1143) and Radiotherapy in Resected LA SCCHN, High Risk, Cisplatin-ineligible Participants (XRAY VISION)TerminatedNCT05386550Phase 3Results posted
• Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-Line Treatment in Participants With PD-L1-Positive (CPS ≥ 1) Recurrent/Metastatic Squamous Cell Carcinoma of the Head and NeckCompletedNCT05287113Phase 2Results posted
• Glycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01)CompletedNCT05259696Phase 1/2Results posted
• Niraparib in the Treatment of Patients With Advanced PALB2 Mutated TumorsTerminatedNCT05169437Phase 2Results posted
• The Role of 5-Aminolevulinic Acid Fluorescence-Guided Surgery in Head and Neck Cancers: a Pilot TrialTerminatedNCT05101798Phase 2Results posted
• Duvelisib Plus Docetaxel In Recurrent/Metastatic HNSCCCompletedNCT05057247Phase 2Results posted
• Assessing Benefits of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Total ThyroidectomyCompletedNCT05022667Not applicableResults posted
• A Clinical Study of TJ004309 With Atezolizumab (TECENTRIQ®) in Patients With Ovarian Cancer and Selected Solid TumorsCompletedNCT05001347Phase 2Results posted
• BEMPEG With Pembrolizumab vs Pembrolizumab Alone in Patients With Metastatic or Recurrent HNSCC (PROPEL-36)TerminatedNCT04969861Phase 2/3Results posted
• Low-Cost, Portable Flexible Nasopharyngoscope in Head & Neck Cancers in Low Resource Settings - Optimization PhaseCompletedNCT04905134Not applicableResults posted
• Dermaprazole Cream for Radiation Dermatitis in Head and Neck CancerCompletedNCT04865731Phase 2Results posted
• A Study of TAK-186 (Also Known as MVC-101) in Adults With Advanced or Metastatic CancerTerminatedNCT04844073Phase 1/2Results posted
• Transdermal Buprenorphine for the Treatment of Radiation-Induced Mucositis Pain in Head and Neck Cancer PatientsCompletedNCT04752384Phase 2Results posted
• Transoral Robotic Surgery for rECurrent Tumours of the Upper Aerodigestive TractCompletedNCT04673929Results posted
• A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid TumorsTerminatedNCT04644315Phase 2Results posted
• Enoblituzumab Plus Retifanlimab or Tebotelimab in Head and Neck CancerTerminatedNCT04634825Phase 2Results posted
• Blinded Dry Mouth Spray Crossover StudyCompletedNCT04608773Not applicableResults posted
• Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck CancerActive, not recruitingNCT04590963Phase 3Results posted
• A Pilot Study Evaluating the Effect of 2D Antiscatter Grids on CBCT Image QualityCompletedNCT04565457Not applicableResults posted
• The HEART Study (Healthy Eating and Recovery Together)CompletedNCT04552587Not applicableResults posted
• Ph 2 Open Label Study of GC4419 to Reduce SOM Associated With Chemoradiotherapy for Head and Neck CancerCompletedNCT04529850Phase 2Results posted
• Dose-Escalated Hypofractionated Adaptive Radiotherapy for Head and Neck CancerCompletedNCT04477759Phase 1Results posted
• Study of GSK3359609 With Pembrolizumab and 5-fluorouracil (5-FU)-Platinum Chemotherapy in Participants With Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaTerminatedNCT04428333Phase 3Results posted
• Bevonescein to Highlight Nerves in Patients Undergoing Head & Neck SurgeryCompletedNCT04420689Phase 1/2Results posted
• Study Evaluating the Efficacy of Niraparib and Dostarlimab (TSR-042) in Recurrent/Metastatic HNSCCCompletedNCT04313504Phase 2Results posted
• Study to Assess the Efficacy and Safety of Nivolumab in Combination With Paclitaxel in Subjects With Head and Neck Cancer Unable for Cisplatin-based Chemotherapy (NIVOTAX)CompletedNCT04282109Phase 2Results posted
• Anti-PD-L1/TGF-beta Trap (M7824) Alone and in Combination With TriAd Vaccine and N-803 for Resectable Head and Neck Squamous Cell Carcinoma Not Associated With Human Papillomavirus InfectionCompletedNCT04247282Phase 1/2Results posted
• Multimodal Pain Study in Free Flap PatientsCompletedNCT04246697Phase 4Results posted
• A Study to Evaluate Enfortumab Vedotin in Subjects With Locally Advanced or Metastatic Malignant Solid Tumors (EV-202)Active, not recruitingNCT04225117Phase 2Results posted
• A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC)TerminatedNCT04222972Phase 3Results posted
• Imaging CCR2 Receptors With 64Cu-DOTA-ECL1i in Head and Neck CancerTerminatedNCT04217057Phase 1Results posted
• Immune Modulation by Abemaciclib in Head and Neck Squamous Cell Carcinoma (HNSCC). (AIM Trial)TerminatedNCT04169074Phase 2Results posted
• Celecoxib Through Surgery and Radiation Therapy for the Treatment of Advanced Head and Neck CancerTerminatedNCT04162873Phase 2Results posted
• Study of GSK3359609 and Pembrolizumab in Programmed Death Receptor 1-ligand 1 (PD-L1) Positive Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaTerminatedNCT04128696Phase 3Results posted
• Central Pain Syndrome in Survivors of Head and Neck CancerTerminatedNCT04128267Not applicableResults posted
• Physiological Flow of Liquids in Head and Neck Cancer Patients: A Pilot StudyCompletedNCT04112940Results posted

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